Human transcript (Homo sapiens)
HIT000092714 (BC032573) APC2 702 aa
Similar to Adenomatous polyposis coli protein 2.
popupCategory II: Similar to known protein NP_005874
alignment locusmaps

arrow_ot Cross-species mapping
Chimpanzee genome
(Pan troglodytes)
Identity / Coverage (amino acid)*: 96.0% / 100.0%
dN/dS in conserved ORF (%length): 0.398 in 58.3% (> 50%)
Window analysis of dN/dS**: No-selection-found
Orangutan genome
(Pongo pygmaeus)
Identity / Coverage (amino acid)*: 99.4% / 100.0%
dN/dS in conserved ORF (%length): 0.052 in 100.0% (> 50%)
Window analysis of dN/dS**: Selection-found
Rhesus monkey genome
(Macaca mulatta)
[partially conserved]
Identity / Coverage (amino acid)*: 95.3% / 100.0%
dN/dS in conserved ORF (%length): 0.105 in 30.6% (≤ 50%)
Window analysis of dN/dS**: Selection-found
* Calculated by FASTY alignment, overriding internal stop codon or frameshift in the primates genome.
** 20-codon with 1-codon step. Fisher's exact test (P < 0.01).

arrow_dl Data download
Sequence (fasta) Transcript, Protein

arrow_go Gene ontology (GO)
Molecular function protein binding GO:0005515
binding GO:0005488
beta-catenin binding GO:0008013
Biological process negative regulation of Wnt receptor signaling pathway GO:0030178

arrow_ip InterPro
Accession number Short name Sequence region (aa)
IPR000225 Armadillo 301-356, 424-475, 477-518, 520-562, 564-609, 614-654, 616-654
IPR011989 Armadillo-like helical 408-698
IPR016024 Armadillo-type fold 342-699
IPR026818 Adenomatous polyposis coli (APC)family 8-702
IPR026831 Adenomatous polyposis coli domain 124-205
IPR026837 Adenomatous polyposis coli 2 8-702