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Statistics

Table 1. Representative AS variant (RASV).

Human Human Mouse Mouse Rat Chimpanzee Macaque Dog
Data set Full-length cDNA mRNA Full-length cDNA mRNA RNA RNA RNA RNA
Transcript total
(Locus)
95160
(27193)
238741
(43538)
121906
(41661)
252615
(75348)
120178
(44077)
92763
(32631)
94104
(35112)
63471
(23757)
RASV
(Locus)
38169
(11538)
60766
(14963)
29756
(10176)
38661
(12025)
22353
(8500)
44687
(11557)
35123
(10651)
29806
(9736)

Table 2. AS pattern of RASV.

Human Human Mouse Mouse Rat Chimpanzee Macaque Dog
Data set Full-length cDNA mRNA Full-length cDNA mRNA RNA RNA RNA RNA

Cassette exon
- including multiple cassette
23176
(6745)
40271
(9420)
11104
(3690)
16343
(4828)
11373
(3903)
30414
(6819)
22022
(6055)
17340
(4714)

Alternative 3' splice
14073
(4040)
25415
(6039)
5736
(2014)
9444
(2944)
9269
(3342)
19668
(4497)
15535
(4456)
15142
(4244)

Alternative 5' splice
13738
(4067)
25069
(6122)
6310
(2205)
9801
(3071)
9532
(3430)
20898
(4921)
16273
(4730)
16124
(4602)

Mutually exclusive exon
2246
(791)
4941
(1393)
545
(191)
1078
(318)
2800
(951)
4895
(1145)
4327
(1387)
4140
(1012)

Retained intron
11432
(3539)
21215
(5403)
7534
(2675)
11436
(3687)
3335
(1285)
10518
(2430)
7784
(2252)
6026
(1838)
5'-end
Alternative first exon
14831
(4295)
25028
(5927)
8685
(2842)
12271
(3567)
6375
(2297)
19282
(4080)
12730
(3326)
7313
(2302)
3'-end
Alternative last exon
6329
(1967)
14647
(3584)
6786
(2251)
8976
(2641)
3661
(1245)
8154
(1967)
5680
(1612)
4232
(1297)

Table 3. AS affecting protein function and Complex AS pattern.

Human Human
Data set Full-length cDNA mRNA
AS affecting protein function total 24249
(7273)
36739
(9824)
Protein motif 19837
(5918)
30753
(7952)
GO 11075
(3052)
15897
(4556)
Subcellular localization signal 19008
(5309)
26384
(7626)
Transmembrane domain 3521
(1105)
6433
(1607)
Complex AS pattern total 3998
(1218)
11463
(2795)
Bridged 1117
(229)
4258
(757)
Nested 2904
(1015)
7582
(2223)
Multiple CDS 113
(46)
367
(125)

Table 4. Equally-spliced variant (ESV) and conserved AS.

A. Human full-length cDNA
vs Mouse
Data set Full-length cDNA
ESV 3060
(2636)
Conserved AS 412
(196)

B. Human mRNA
vs Mouse vs Rat vs Chimpanzee vs Macaque vs Dog
Data set mRNA RNA RNA RNA RNA
ESV 5071
(3979)
2717
(2084)
7679
(4266)
7116
(3917)
4261
(2961)
Conserved AS 1148
(484)
730
(292)
5177
(1998)
4894
(1880)
1663
(654)