H-InvDB x AHG DB
Gene family annotation
H-InvDB_8.3 released on March 26, 2013.
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H-InvDB Gene Families/Groups

Predicted human gene family/group (HIF0000005 to HIF0003438) [Download]

Description: We defined predicted human gene families/groups based on the sequence similarities and assigned an HIF ID for each H-Inv gene family/group. A unique HIF ID is assigned to each group of H-Inv cluster entries identifying the groupings of the human gene in a context of sequence similarity and conservation of functional motif.

No. HIF Gene family/group name No. of HIX clusters Evidence InterPro ID
1 HIF0000005 Zinc finger, C2H2-type (IPR007087). 681 IPR007087
2 HIF0000006 7TM GPCR, rhodopsin-like (IPR000276). 209 IPR000276
3 HIF0000007 Nucleotide-binding, alpha-beta plait (IPR012677). 105 IPR012677
4 HIF0000008 Small GTP-binding protein (IPR005225). 174 IPR005225
5 HIF0000010 Protein kinase, core (IPR000719). 154 IPR000719
6 HIF0000011 Peptidase S1 and S6, chymotrypsin/Hap (IPR001254). 124 IPR001254
7 HIF0000012 B302 (SPRY)-like (IPR001870). 92 IPR001870
8 HIF0000013 Intermediate filament protein (IPR001664). 62 IPR001664
9 HIF0000015 Nuclear hormone receptor, ligand-binding, core (IPR000536). 61 IPR000536
10 HIF0000016 EF-Hand type (IPR011992). 50 IPR011992
11 HIF0000017 Tubulin (IPR000217). 50 IPR000217
12 HIF0000019 Collagen triple helix repeat (IPR008160). 45 IPR008160
13 HIF0000020 Peptidase M10A and M12B, matrixin and adamalysin (IPR001818). 44 IPR001818
14 HIF0000021 Mitochondrial substrate carrier (IPR001993). 42 IPR001993
15 HIF0000022 BTB/Kelch-associated (IPR011705). 37 IPR011705
16 HIF0000023 Actin/actin-like (IPR004000). 23 IPR004000
17 HIF0000025 Ankyrin (IPR002110). 31 IPR002110
18 HIF0000026 Protease inhibitor I4, serpin (IPR000215). 30 IPR000215
19 HIF0000028 Tetraspanin (IPR018499). 26 IPR018499
20 HIF0000029 Cytochrome P450 (IPR001128). 26 IPR001128
21 HIF0000030 Transcription factor, fork head (IPR001766). 22 IPR001766
22 HIF0000031 Homeobox (IPR001356). 27 IPR001356
23 HIF0000032 Ubiquitin-conjugating enzyme, E2 (IPR000608). 23 IPR000608
24 HIF0000033 Blood coagulation inhibitor, Disintegrin (IPR001762). 25 IPR001762
25 HIF0000034 Interferon-induced transmembrane protein (IPR007593). 22 IPR007593
26 HIF0000035 Short-chain dehydrogenase/reductase SDR (IPR002198). 26 IPR002198
27 HIF0000036 RNA helicase, DEAD-box type, Q motif (IPR014014). 27 IPR014014
28 HIF0000037 Tyrosine protein kinase (IPR001245). 26 IPR001245
29 HIF0000038 Short-chain dehydrogenase/reductase SDR (IPR002198). 24 IPR002198
30 HIF0000039 Ricin B lectin (IPR000772). 25 IPR000772
31 HIF0000040 MAGE protein (IPR002190). 22 IPR002190
32 HIF0000042 Mammalian taste receptor (IPR007960). 25 IPR007960
33 HIF0000043 Potassium channel, voltage dependent, Kv, tetramerisation (IPR003131). 24 IPR003131
34 HIF0000044 Human gene family/group candidate, HIF0000044. 12
35 HIF0000045 Myosin head, motor region (IPR001609). 21 IPR001609
36 HIF0000046 Helicase-associated region (IPR007502). 23 IPR007502
37 HIF0000049 Tumour necrosis factor-like (IPR008983). 23 IPR008983
38 HIF0000050 Neurotransmitter-gated ion-channel (IPR006201). 22 IPR006201
39 HIF0000051 Cytosolic fatty-acid binding (IPR000463). 17 IPR000463
40 HIF0000052 Arf GTPase activating protein (IPR001164). 16 IPR001164
41 HIF0000053 C2 calcium-dependent membrane targeting (IPR000008). 22 IPR000008
42 HIF0000054 Neurotransmitter-gated ion-channel (IPR006201). 22 IPR006201
43 HIF0000055 Glutathione S-transferase/chloride channel, C-terminal (IPR017933). 21 IPR017933
44 HIF0000056 bZIP transcription factor, bZIP-1 (IPR011616). 15 IPR011616
45 HIF0000057 Heat shock protein 70 (IPR013126). 17 IPR013126
46 HIF0000058 ADAM-TS Spacer 1 (IPR010294). 20 IPR010294
47 HIF0000060 Interleukin 1/heparin-binding growth factor (IPR002348). 17 IPR002348
48 HIF0000061 Wnt superfamily (IPR005817). 20 IPR005817
49 HIF0000062 Immunoglobulin subtype 2 (IPR003598). 20 IPR003598
50 HIF0000065 Sodium:neurotransmitter symporter (IPR000175). 19 IPR000175
51 HIF0000066 Potassium channel, inwardly rectifying, Kir (IPR016449). 20 IPR016449
52 HIF0000067 Connexins (IPR000500). 15 IPR000500
53 HIF0000068 Carbonic anhydrase, alpha-class, catalytic domain (IPR001148). 19 IPR001148
54 HIF0000069 Sulphate transporter (IPR011547). 18 IPR011547
55 HIF0000070 Dynein heavy chain (IPR004273). 20 IPR004273
56 HIF0000072 Transforming growth factor-beta-related (IPR015615). 19 IPR015615
57 HIF0000073 UDP-glucuronosyl/UDP-glucosyltransferase (IPR002213). 15 IPR002213
58 HIF0000074 Immunoglobulin-like fold (IPR013783). 17 IPR013783
59 HIF0000075 EF-Hand type (IPR011992). 16 IPR011992
60 HIF0000076 Claudin (IPR006187). 16 IPR006187
61 HIF0000077 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (IPR001757). 16 IPR001757
62 HIF0000078 Annexin (IPR001464). 13 IPR001464
63 HIF0000082 Human gene family/group candidate, HIF0000082. 13
64 HIF0000083 G-protein, gamma subunit (IPR001770). 14 IPR001770
65 HIF0000084 EF-Hand type (IPR011992). 17 IPR011992
66 HIF0000085 Interferon alpha/beta/delta (IPR000471). 17 IPR000471
67 HIF0000086 Aldo/keto reductase (IPR001395). 13 IPR001395
68 HIF0000087 Pancreatic ribonuclease (IPR001427). 17 IPR001427
69 HIF0000088 Guanine nucleotide binding protein (G-protein), alpha subunit (IPR001019). 16 IPR001019
70 HIF0000089 Semaphorin/CD100 antigen (IPR001627). 17 IPR001627
71 HIF0000090 Glycosyl transferase, family 31 (IPR002659). 17 IPR002659
72 HIF0000091 Immunoglobulin E-set (IPR014756). 15 IPR014756
73 HIF0000094 7TM GPCR, rhodopsin-like (IPR000276). 16 IPR000276
74 HIF0000095 GPCR, family 2, extracellular region (IPR001879). 16 IPR001879
75 HIF0000096 Valyl-tRNA synthetase, class Ia (IPR002303). 15 IPR002303
76 HIF0000098 Homeobox (IPR001356). 15 IPR001356
77 HIF0000099 ABC transporter, transmembrane region (IPR001140). 15 IPR001140
78 HIF0000100 Chaperonin Cpn60/TCP-1 (IPR002423). 14 IPR002423
79 HIF0000101 Tumor Necrosis Factor (IPR006052). 16 IPR006052
80 HIF0000102 LST-1 (IPR007775). 12 IPR007775
81 HIF0000103 ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (IPR001757). 15 IPR001757
82 HIF0000104 Cell division/GTP binding protein (IPR000038). 16 IPR000038
83 HIF0000109 Adenylyl cyclase class-3/4/guanylyl cyclase (IPR001054). 15 IPR001054
84 HIF0000113 Galectin, carbohydrate recognition domain (IPR001079). 12 IPR001079
85 HIF0000114 Metallothionein, vertebrate (IPR000006). 12 IPR000006
86 HIF0000116 General substrate transporter (IPR005828). 12 IPR005828
87 HIF0000118 Immunoglobulin V-set (IPR013106). 13 IPR013106
88 HIF0000123 Ran Binding Protein 1 (IPR000156). 12 IPR000156
89 HIF0000124 Protein of unknown function DUF738 (IPR007965). 14 IPR007965
90 HIF0000126 Fibrinogen, alpha/beta/gamma chain, C-terminal globular (IPR002181). 14 IPR002181
91 HIF0000129 Alpha/beta hydrolase fold-1 (IPR000073). 14 IPR000073
92 HIF0000130 Tumor Necrosis Factor (IPR006052). 14 IPR006052
93 HIF0000131 ABC transporter, transmembrane region (IPR001140). 14 IPR001140
94 HIF0000137 Zinc finger, LIM-type (IPR001781). 13 IPR001781
95 HIF0000138 Armadillo-type fold (IPR016024). 12 IPR016024
96 HIF0000139 Sterile alpha motif SAM (IPR001660). 13 IPR001660
97 HIF0000141 Molecular chaperone, heat shock protein, Hsp40, DnaJ (IPR015609). 13 IPR015609
98 HIF0000143 Immunoglobulin subtype (IPR003599). 13 IPR003599
99 HIF0000153 Beta and gamma crystallin (IPR001064). 12 IPR001064
100 HIF0000156 Ion transport 2 (IPR013099). 12 IPR013099