H-InvDB x AHG DB
H-InvDB x AHG DB
H-InvDB_9.0 released on May 27, 2015.
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Protein complex view - Annotation for protein complex 24
Complex type: 

Protein complex & functional unit (mixed)
Functional category(ries): 

Cell cycle, Transcription
Subcellular localization(s): 

Nucleus
Complex name: 

DREAM complex
Description and evidences: 

DREAM complex is tightly bound to E2F-regulated promoters in G0 and dissociates from these promoters in S phase. Some subunits of the DREAM complex can also interact specifically with MYB and may be involved in expression of MYB-dependent genes important into the G2/M progression.[PMID: 17531812]
CQI:  10.1.2/13  (Complex Annotation Quality Check Index: ../Total proteins)
*CQI is come from  
the defined categories of  
complex member proteins: 
: A protein of Catg.I has structural or document based evidences (scientific literatures or textbooks) to be the complex.
: A protein of Catg.II has a related function to other member proteins of the complex.
: A protein of Catg.III is just predicted as a complex member by our network analysis.
Tools & Another Search

Draw PPI map of this complex.


PubMed reference ID relations

PPI data are based on H-InvDB Rel. 5.0
[Complex list] - [PCDq TOP]
for

Protein Summary for Complex 24
13
---
155
Complex 24

HIX IDs &
(Gene locus)
H-ANGEL Exp-profiles
PDB IDs InterPro domains Gene Ontology (GO)
  BP: Biological Process
  CC: Cellular Component
  MF: Molecular Function
Subcellular
localizations
1

HIP000013164(5) PPI view Transcript viewCatg. IV(4)/4 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Gene symbol: LIN52
Definition:
1. Conserved hypothetical protein.
HIX0019435
  Link to LOCUS view
  Link to H-ANGEL
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
2

HIP000021425(3) PPI view Transcript viewRep, Catg. I(1), III(3)/4 HIT IDs
UniProt: , RefSeq: NP_001077057, GI: 134142809, CCDS:
Gene symbol: E2F5
Definition:
1. E2F Family family protein.
2. E2F transcription factor 5 isoform 2.
HIX0034366
  Link to LOCUS view
  Link to H-ANGEL
IPR003316
Transcription factor E2F/dimerisation partner (TDP) [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
IPR015633
E2F Family [Family]
BP:0000074
regulation of progression through cell cycle
BP:0006355
regulation of transcription, DNA-dependent
CC:0005667
transcription factor complex
MF:0003700
transcription factor activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
3

HIP000024799(27) PPI view Transcript viewRep, Catg. I(6), II(1)/7 HIT IDs
UniProt: Q09028, Q3MHL3, RefSeq: NP_005601, GI: 5032027, CCDS: CCDS366
Shared with Complex 54, Complex 1258.
Gene symbol: RBBP4
Definition:
1. Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).
2. Similar to Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome remodeling factor subunit RBAP48).
3. WD40-like domain containing protein.
HIX0000377
  Link to LOCUS view
  Link to H-ANGEL
IPR001680
WD40 repeat [Repeat]
IPR011046
WD40-like [Domain]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
4

HIP000025285(15) PPI view Transcript viewRep, Catg. I(6)/6 HIT IDs
UniProt: Q16254, RefSeq: NP_001941, GI: 12669915, CCDS: CCDS32464
Gene symbol: E2F4
Definition:
1. E2F Family family protein.
2. Transcription factor E2F4 (E2F-4).
HIX0013138
  Link to LOCUS view
  Link to H-ANGEL
IPR003316
Transcription factor E2F/dimerisation partner (TDP) [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
IPR015633
E2F Family [Family]
BP:0000074
regulation of progression through cell cycle
BP:0006355
regulation of transcription, DNA-dependent
CC:0005667
transcription factor complex
MF:0003700
transcription factor activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
5

HIP000028655(12) PPI view Transcript viewRep, Catg. I(1), III(1)/2 HIT IDs
UniProt: Q14186, Q5JSB4, RefSeq: NP_009042, GI: 6005900, CCDS: CCDS9538
Shared with Complex 632.
Gene symbol: TFDP1
Definition:
1. Transcription factor DP family protein.
2. Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1- polypeptide 1) (DRTF1).
HIX0011480
  Link to LOCUS view
  Link to H-ANGEL
IPR003316
Transcription factor E2F/dimerisation partner (TDP) [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
IPR014889
Transcription factor DP, C-terminal [Domain]
IPR015648
Transcription factor DP [Family]
BP:0000074
regulation of progression through cell cycle
BP:0006355
regulation of transcription, DNA-dependent
CC:0005667
transcription factor complex
MF:0003700
transcription factor activity
WoLF PSORT
cytosol, nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
6

HIP000028983(3) PPI view Transcript viewRep, Catg. II(1)/1 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Gene symbol: MYBL1
Definition:
1. Myb transcription factor family protein.
2. Similar to Myb-related protein A (A-Myb).
HIX0034339
  Link to LOCUS view
  Link to H-ANGEL
IPR001005
SANT, DNA-binding [Domain]
IPR009057
Homeodomain-like [Domain]
IPR012287
Homeodomain-related [Domain]
IPR012642
Mitotic Wos2 [Domain]
IPR014778
Myb, DNA-binding [Domain]
IPR015395
C-myb, C-terminal [Domain]
IPR015495
Myb transcription factor [Family]
BP:0045449
regulation of transcription
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0030528
transcription regulator activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
7

HIP000051828(30) PPI view Transcript viewRep, Catg. II(1)/1 HIT IDs
UniProt: Q6MZP7, RefSeq: NP_919258, GI: 34996483, CCDS:
Gene symbol: LIN54
Definition:
1. Similar to Tesmin (Metallothionein-like 5, testis-specific) (Testis-specific metallothionein-like protein).
2. Tesmin/TSO1-like, CXC domain containing protein.
HIX0024607
  Link to LOCUS view
  Link to H-ANGEL
IPR005172
Tesmin/TSO1-like, CXC [Domain]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
8

HIP000053526(22) PPI view Transcript viewRep, Catg. IV(1)/1 HIT IDs
UniProt: Q96GY3, RefSeq: NP_061977, GI: 28144916, CCDS:
Definition:
1. Conserved hypothetical protein.
HIX0015039
  Link to LOCUS view
  Link to H-ANGEL
WoLF PSORT
nuclear, cytosol, extracellular, golgi apparatus, lysosome, mitochondria, plasma membrane
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
9

HIP000063143(13) PPI view Transcript viewRep, Catg. I(5)/5 HIT IDs
UniProt: Q5TKA1-2, RefSeq: NP_775106, GI: 32996737, CCDS: CCDS1553
Gene symbol: LIN9
Definition:
1. DIRP family protein.
2. Lin-9 homolog (huLin-9) (hLin-9) (Beta-subunit associated regulator of apoptosis) (Type I interferon receptor beta chain-associated protein) (TUDOR gene similar protein) (pRB-associated protein).
HIX0023586
  Link to LOCUS view
  Link to H-ANGEL
IPR010561
DIRP [Family]
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
10

HIP000085571(92) PPI view Transcript viewRep, Catg. I(1), III(6)/7 HIT IDs
UniProt: P06400, RefSeq: NP_000312, GI: 108773787, CCDS: CCDS31973
Shared with Complex 4, Complex 632, Complex 1083, Complex 1164, Complex 1271.
Gene symbol: RB1
Definition:
1. Retinoblastoma-associated protein (PP110) (P105-RB) (RB).
2. Retinoblastoma-associated protein family protein.
HIX0026565
  Link to LOCUS view
  Link to H-ANGEL
IPR002719
Retinoblastoma-associated protein, B-box [Domain]
IPR002720
Retinoblastoma-associated protein, A-box [Domain]
IPR006670
Cyclin [Domain]
IPR011028
Cyclin-like [Domain]
IPR013763
Cyclin-related [Domain]
IPR015030
Rb C-terminal [Domain]
IPR015652
Retinoblastoma-associated protein [Family]
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
11

HIP000086599(24) PPI view Transcript viewRep, Catg. I(3)/3 HIT IDs
UniProt: Q08999, RefSeq: , GI: , CCDS: CCDS10748
Gene symbol: RBL2
Definition:
1. Retinoblastoma-associated protein, A-box domain containing protein.
2. Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).
HIX0026969
  Link to LOCUS view
  Link to H-ANGEL
IPR002719
Retinoblastoma-associated protein, B-box [Domain]
IPR002720
Retinoblastoma-associated protein, A-box [Domain]
IPR006670
Cyclin [Domain]
IPR011028
Cyclin-like [Domain]
IPR013763
Cyclin-related [Domain]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
12

HIP000102379(9) PPI view Transcript viewRep, Catg. I(4)/4 HIT IDs
UniProt: P10244, RefSeq: NP_002457, GI: 4505293, CCDS: CCDS13322
Gene symbol: MYBL2
Definition:
1. Myb transcription factor family protein.
2. Myb-related protein B (B-Myb).
HIX0015830
  Link to LOCUS view
  Link to H-ANGEL
IPR001005
SANT, DNA-binding [Domain]
IPR009057
Homeodomain-like [Domain]
IPR012287
Homeodomain-related [Domain]
IPR014778
Myb, DNA-binding [Domain]
IPR015395
C-myb, C-terminal [Domain]
IPR015495
Myb transcription factor [Family]
BP:0045449
regulation of transcription
CC:0005634
nucleus
MF:0003677
DNA binding
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
13

HIP000105389(11) PPI view Transcript viewRep, Catg. I(1)/1 HIT IDs
UniProt: Q14188, RefSeq: , GI: , CCDS:
Gene symbol: TFDP2
Definition:
1. Transcription factor DP family protein.
2. Transcription factor Dp-2 (E2F dimerization partner 2).
HIX0003733
  Link to LOCUS view
  Link to H-ANGEL
IPR003316
Transcription factor E2F/dimerisation partner (TDP) [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
IPR014889
Transcription factor DP, C-terminal [Domain]
IPR015648
Transcription factor DP [Family]
BP:0000074
regulation of progression through cell cycle
BP:0006355
regulation of transcription, DNA-dependent
CC:0005667
transcription factor complex
MF:0003700
transcription factor activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
14 HIP000013588(2) PPI view Transcript viewCatg. II(1)/1 HIT IDs
UniProt: Q6P142, RefSeq: , GI: , CCDS:
Gene symbol: LIN9
Definition:
1. DIRP family protein.
2. Similar to Lin-9 homolog (huLin-9) (hLin-9) (Beta-subunit associated regulator of apoptosis) (Type I interferon receptor beta chain-associated protein) (TUDOR gene similar protein) (pRB-associated protein).
HIX0023586
  Link to LOCUS view
  Link to H-ANGEL
IPR010561
DIRP [Family]
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
15 HIP000021464(2) PPI view Transcript viewCatg. I(3)/3 HIT IDs
UniProt: Q9H1K1, RefSeq: , GI: , CCDS:
Gene symbol: ISCU
Definition:
1. ISC system FeS cluster assembly, IscU scaffold family protein.
2. Iron-sulfur cluster assembly enzyme isoform ISCU2 precursor.
HIX0010967
  Link to LOCUS view
  Link to H-ANGEL
IPR002871
NIF system FeS cluster assembly, NifU, N-terminal [Domain]
IPR011339
ISC system FeS cluster assembly, IscU scaffold [Family]
BP:0016226
iron-sulfur cluster assembly
MF:0005506
iron ion binding
MF:0005515
protein binding
MF:0051536
iron-sulfur cluster binding
WoLF PSORT
mitochondria
Target P
mitochondria
SOSUI
soluble protein
TMHMM
soluble protein
16 HIP000022105(10) PPI view Transcript viewRep, Catg. I(7), II(2)/9 HIT IDs
UniProt: Q5RBG3, Q9UNZ2, RefSeq: NP_057227, GI: 20149635, CCDS: CCDS13015
Shared with Complex 423.
Gene symbol: NSFL1C
Definition:
1. NSFL1 cofactor p47 (p97 cofactor p47).
2. Similar to NSFL1 cofactor p47 (p97 cofactor p47).
3. UBX domain containing protein.
HIX0015565
  Link to LOCUS view
  Link to H-ANGEL
IPR001012
UBX [Domain]
IPR006556
Protein of unknown function FAF1 [Domain]
IPR009060
UBA-like [Domain]
IPR012989
SEP [Domain]
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
17 HIP000022920(8) PPI view Transcript viewRep, Catg. I(2)/2 HIT IDs
UniProt: P39880-3, RefSeq: , GI: , CCDS:
Shared with Complex 351.
Definition:
1. CCAAT displacement protein isoform a.
2. Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP). Isoform 3.
3. Homeodomain protein CUT containing protein.
HIX0025289
  Link to LOCUS view
  Link to H-ANGEL
IPR001356
Homeobox [Domain]
IPR003350
Homeodomain protein CUT [Domain]
IPR009057
Homeodomain-like [Domain]
IPR010982
Lambda repressor-like, DNA-binding [Domain]
IPR012287
Homeodomain-related [Domain]
BP:0006355
regulation of transcription, DNA-dependent
BP:0045449
regulation of transcription
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0003700
transcription factor activity
MF:0043565
sequence-specific DNA binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
18 HIP000023181(7) PPI view Transcript viewRep, Catg. I(2), II(2)/4 HIT IDs
UniProt: P42575, RefSeq: NP_116764, GI: 39995059, CCDS: CCDS5879
Shared with Complex 199.
Gene symbol: CASP2
EC No.: EC 3.4.22.55
Definition:
1. Caspase-2 precursor (EC 3.4.22.55) (CASP-2) (ICH-1 protease) (ICH- 1L/1S) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].
2. Peptidase C14, caspase precursor p45 family protein.
3. Similar to Caspase-2 precursor (EC 3.4.22.55) (CASP-2) (ICH-1 protease) (ICH- 1L/1S) [Contains: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12].
HIX0007169
  Link to LOCUS view
  Link to H-ANGEL
IPR001309
Caspase, p20 subunit [Domain]
IPR001315
Caspase Recruitment [Domain]
IPR002138
Peptidase C14, caspase non-catalytic subunit p10 [Domain]
IPR002398
Peptidase C14, caspase precursor p45 [Family]
IPR011029
DEATH-like [Domain]
IPR011600
Peptidase C14, caspase catalytic [Domain]
BP:0006508
proteolysis
BP:0042981
regulation of apoptosis
CC:0005622
intracellular
MF:0005515
protein binding
MF:0030693
caspase activity
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
19 HIP000023706(15) PPI view Transcript viewRep, Catg. I(4), II(1)/5 HIT IDs
UniProt: , RefSeq: NP_055781, GI: 20336290, CCDS:
Shared with Complex 54.
Gene symbol: DHX30
Definition:
1. DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1.
2. DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2.
3. Double-stranded RNA binding domain containing protein.
4. Similar to DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1.
HIX0003277
  Link to LOCUS view
  Link to H-ANGEL
IPR001159
Double-stranded RNA binding [Domain]
IPR001650
Helicase, C-terminal [Domain]
IPR002464
ATP-dependent helicase, DEAH-box [Domain]
IPR007502
Helicase-associated region [Domain]
IPR011545
DEAD/DEAH box helicase, N-terminal [Domain]
IPR011709
Domain of unknown function DUF1605 [Domain]
IPR014001
DEAD-like helicases, N-terminal [Domain]
IPR014021
Helicase superfamily 1 and 2 ATP-binding [Domain]
CC:0005622
intracellular
MF:0003676
nucleic acid binding
MF:0003725
double-stranded RNA binding
MF:0004386
helicase activity
MF:0005524
ATP binding
MF:0008026
ATP-dependent helicase activity
WoLF PSORT

Target P
Other
SOSUI
membrane protein
TMHMM
soluble protein
20 HIP000024160(3) PPI view Transcript viewRep, Catg. I(1), III(1)/2 HIT IDs
UniProt: Q8N6F6, RefSeq: NP_758961, GI: 27363484, CCDS: CCDS9374
Gene symbol: ELF1
Definition:
1. E74-like factor 1 (ets domain transcription factor).
2. Ets domain containing protein.
HIX0011262
  Link to LOCUS view
  Link to H-ANGEL
IPR000418
Ets [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
BP:0006355
regulation of transcription, DNA-dependent
CC:0005634
nucleus
MF:0003700
transcription factor activity
MF:0043565
sequence-specific DNA binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
21 HIP000024567(24) PPI view Transcript viewCatg. I(8), III(2)/10 HIT IDs
UniProt: P55210, Q5SVL0, RefSeq: NP_203125, GI: 4502581, CCDS: CCDS7581
Shared with Complex 405.
Gene symbol: CASP7
EC No.: EC 3.4.22.60
Definition:
1. Caspase-7 precursor (EC 3.4.22.60) (CASP-7) (ICE-like apoptotic protease 3) (ICE-LAP3) (Apoptotic protease Mch-3) (CMH-1) [Contains: Caspase-7 subunit p20; Caspase-7 subunit p11].
2. Peptidase C14, caspase precursor p45 family protein.
HIX0009219
  Link to LOCUS view
  Link to H-ANGEL
1f1j_A
1f1j_B
1kmc_A
1kmc_B
IPR001309
Caspase, p20 subunit [Domain]
IPR002138
Peptidase C14, caspase non-catalytic subunit p10 [Domain]
IPR002398
Peptidase C14, caspase precursor p45 [Family]
IPR011600
Peptidase C14, caspase catalytic [Domain]
IPR015471
Caspase-7 [Family]
BP:0006508
proteolysis
MF:0030693
caspase activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
22 HIP000024666(5) PPI view Transcript viewCatg. III(1)/1 HIT IDs
UniProt: Q15056, RefSeq: XP_949532, GI: 89026104, CCDS: CCDS5564
Shared with Complex 1286.
Definition:
1. RNA recognition motif, RNP-1 domain containing protein.
HIX0006763
  Link to LOCUS view
  Link to H-ANGEL
IPR000504
RNA recognition motif, RNP-1 [Domain]
MF:0000166
nucleotide binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
23 HIP000025023(4) PPI view Transcript viewRep, Catg. I(1), III(2)/3 HIT IDs
UniProt: Q00577, RefSeq: NP_005850, GI: 5032007, CCDS: CCDS4220
Gene symbol: PURA
Definition:
1. PUR-alpha/beta/gamma, DNA/RNA-binding family protein.
2. Transcriptional activator protein Pur-alpha (Purine-rich single- stranded DNA-binding protein alpha).
HIX0032059
  Link to LOCUS view
  Link to H-ANGEL
IPR006628
PUR-alpha/beta/gamma, DNA/RNA-binding [Family]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
24 HIP000025697(2) PPI view Transcript viewRep, Catg. I(3), II(2), IV(2)/7 HIT IDs
UniProt: Q92966, RefSeq: NP_001034786, GI: 89242152, CCDS:
Shared with Complex 1271.
Gene symbol: SNAPC3
Definition:
1. Conserved hypothetical protein.
2. Similar to snRNA-activating protein complex subunit 3 (SNAPc subunit 3) (Small nuclear RNA-activating complex polypeptide 3) (snRNA-activating protein complex 50 kDa subunit) (SNAPc 50 kDa subunit) (Proximal sequence element-binding transcription factor subunit beta) (PSE- binding factor subunit beta) (PTF subunit beta).
3. snRNA-activating protein complex subunit 3 (SNAPc subunit 3) (Small nuclear RNA-activating complex polypeptide 3) (snRNA-activating protein complex 50 kDa subunit) (SNAPc 50 kDa subunit) (Proximal sequence element-binding transcription factor subunit beta) (PSE- binding factor subunit beta) (PTF subunit beta).
HIX0025738
  Link to LOCUS view
  Link to H-ANGEL
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
25 HIP000026391(25) PPI view Transcript viewRep, Catg. I(5)/5 HIT IDs
UniProt: , RefSeq: NP_001609, GI: 4501955, CCDS:
Shared with Complex 90.
Gene symbol: PARP1
EC No.: EC 2.4.2.30
Definition:
1. NAD+ ADP-ribosyltransferase family protein.
2. Poly (ADP-ribose) polymerase family, member 1.
HIX0023551
  Link to LOCUS view
  Link to H-ANGEL
IPR001290
Poly(ADP-ribose) polymerase, catalytic region [Domain]
IPR001357
BRCT [Domain]
IPR001510
Zinc finger, PARP-type [Domain]
IPR004102
Poly(ADP-ribose) polymerase, regulatory region [Domain]
IPR008288
NAD+ ADP-ribosyltransferase [Family]
IPR008893
WGR [Domain]
IPR012317
PARP, catalytic [Domain]
IPR012982
PADR1 [Domain]
BP:0006471
protein amino acid ADP-ribosylation
CC:0005622
intracellular
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0003950
NAD+ ADP-ribosyltransferase activity
MF:0008270
zinc ion binding
MF:0051287
NAD binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
26 HIP000026417(2) PPI view Transcript viewRep, Catg. I(1), III(15)/16 HIT IDs
UniProt: O75506, Q53XA8, RefSeq: NP_001528, GI: 4557647, CCDS:
Gene symbol: HSBP1
Definition:
1. Heat shock factor binding 1 family protein.
2. Heat shock factor-binding protein 1 (Nasopharyngeal carcinoma- associated antigen 13) (NPC-A-13).
HIX0013282
  Link to LOCUS view
  Link to H-ANGEL
IPR009643
Heat shock factor binding 1 [Family]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
27 HIP000026893(23) PPI view Transcript viewRep, Catg. I(1), III(1)/2 HIT IDs
UniProt: Q9Y4A5-2, RefSeq: NP_003487, GI: 4507691, CCDS: CCDS5659
Shared with Complex 11, Complex 166.
Gene symbol: TRRAP
Definition:
1. PIK-related kinase, FAT domain containing protein.
2. Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog). Isoform 2.
HIX0006883
  Link to LOCUS view
  Link to H-ANGEL
IPR000403
Phosphatidylinositol 3- and 4-kinase, catalytic [Domain]
IPR003151
PIK-related kinase, FAT [Domain]
IPR003152
PIK-related kinase, FATC [Domain]
IPR011009
Protein kinase-like [Domain]
IPR014009
PIK-related kinase [Domain]
MF:0016773
phosphotransferase activity, alcohol group as acceptor
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
28 HIP000028095(5) PPI view Transcript viewRep, Catg. I(2)/2 HIT IDs
UniProt: P29375, RefSeq: , GI: , CCDS:
Gene symbol: JARID1A
Definition:
1. Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).
2. Retinoblastoma binding protein 2 isoform 1.
3. Transcription factor jumonji, JmjN domain containing protein.
HIX0010308
  Link to LOCUS view
  Link to H-ANGEL
IPR001606
AT-rich interaction region [Domain]
IPR001965
Zinc finger, PHD-type [Domain]
IPR003347
Transcription factor jumonji/aspartyl beta-hydroxylase [Domain]
IPR003349
Transcription factor jumonji, JmjN [Domain]
IPR004198
Zinc finger, C5HC2-type [Domain]
IPR011011
Zinc finger, FYVE/PHD-type [Domain]
IPR013129
Transcription factor jumonji [Domain]
IPR013637
PLU-1-like [Domain]
CC:0005622
intracellular
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0005515
protein binding
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
29 HIP000029067(26) PPI view Transcript viewRep, Catg. I(10)/10 HIT IDs
UniProt: O15379, RefSeq: NP_003874, GI: 13128862, CCDS: CCDS4264
Shared with Complex 54, Complex 162.
Gene symbol: HDAC3
Definition:
1. Histone deacetylase 3 (HD3) (RPD3-2) (SMAP45).
2. Histone deacetylase 3 (HD3) (RPD3-2) (SMAP45). Isoform 2.
3. Histone deacetylase superfamily protein.
HIX0005255
  Link to LOCUS view
  Link to H-ANGEL
IPR000286
Histone deacetylase superfamily [Family]
IPR003084
Histone deacetylase [Family]
BP:0016575
histone deacetylation
CC:0005634
nucleus
MF:0004407
histone deacetylase activity
WoLF PSORT
cytosol, nuclear, extracellular, Other
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
30 HIP000029095(23) PPI view Transcript viewRep, Catg. I(1), III(24)/25 HIT IDs
UniProt: Q9NVP2, RefSeq: NP_060624, GI: 8922549, CCDS: CCDS12306
Shared with Complex 158.
Gene symbol: ASF1B
Definition:
1. Anti-silencing function 1B.
2. Anti-silencing protein, ASF1-like family protein.
HIX0014833
  Link to LOCUS view
  Link to H-ANGEL
IPR006818
Anti-silencing protein, ASF1-like [Family]
BP:0006333
chromatin assembly or disassembly
CC:0005634
nucleus
WoLF PSORT
extracellular, cytosol, nuclear, Other
Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
31 HIP000029147(23) PPI view Transcript viewCatg. I(4)/4 HIT IDs
UniProt: Q01094, RefSeq: NP_005216, GI: 12669911, CCDS: CCDS13224
Gene symbol: E2F1
Definition:
1. Transcription Factor E2F1 family protein.
2. Transcription factor E2F1 (E2F-1) (Retinoblastoma-binding protein 3) (RBBP-3) (PRB-binding protein E2F-1) (PBR3) (Retinoblastoma-associated protein 1) (RBAP-1).
HIX0027663
  Link to LOCUS view
  Link to H-ANGEL
IPR003316
Transcription factor E2F/dimerisation partner (TDP) [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
IPR015633
E2F Family [Family]
IPR015634
Transcription Factor E2F1 [Family]
BP:0000074
regulation of progression through cell cycle
BP:0006355
regulation of transcription, DNA-dependent
CC:0005667
transcription factor complex
MF:0003700
transcription factor activity
WoLF PSORT
nuclear, cytosol
Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
32 HIP000029455(41) PPI view Transcript viewCatg. I(2)/2 HIT IDs
UniProt: P33993, RefSeq: NP_005907, GI: 33469968, CCDS: CCDS5683
Shared with Complex 34.
Gene symbol: MCM7
Definition:
1. DNA replication licensing factor MCM7 (CDC47 homolog) (P1.1-MCM3).
2. MCM family protein.
HIX0006907
  Link to LOCUS view
  Link to H-ANGEL
IPR001208
MCM [Family]
IPR003593
AAA+ ATPase, core [Domain]
IPR008050
MCM protein 7 [Family]
IPR012340
Nucleic acid-binding, OB-fold [Domain]
BP:0006270
DNA replication initiation
CC:0005634
nucleus
MF:0000166
nucleotide binding
MF:0003677
DNA binding
MF:0005524
ATP binding
MF:0008094
DNA-dependent ATPase activity
MF:0017111
nucleoside-triphosphatase activity
WoLF PSORT
nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
33 HIP000029710(4) PPI view Transcript viewRep, Catg. I(1), III(4)/5 HIT IDs
UniProt: Q9NYL9, RefSeq: NP_055362, GI: 7657649, CCDS: CCDS10145
Gene symbol: TMOD3
Definition:
1. Tropomodulin family protein.
2. Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod).
HIX0012250
  Link to LOCUS view
  Link to H-ANGEL
IPR004934
Tropomodulin [Family]
CC:0005856
cytoskeleton
MF:0005523
tropomyosin binding
WoLF PSORT
cytosol, nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
34 HIP000031279(1) PPI view Transcript viewRep, Catg. II(1), III(4)/5 HIT IDs
UniProt: Q96A32, RefSeq: NP_037424, GI: 28372499, CCDS: CCDS10677
Definition:
1. Calcium-binding EF-hand domain containing protein.
2. Similar to Myosin regulatory light chain 2, skeletal muscle isoform type 2 (Fast skeletal myosin light chain 2) (G2) (DTNB) (MLC-2).
HIX0012954
  Link to LOCUS view
  Link to H-ANGEL
IPR002048
Calcium-binding EF-hand [Domain]
IPR011992
EF-Hand type [Domain]
MF:0005509
calcium ion binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
35 HIP000031494(4) PPI view Transcript viewRep, Catg. I(2)/2 HIT IDs
UniProt: , RefSeq: NP_056170, GI: 15149470, CCDS:
Shared with Complex 84, Complex 768.
Gene symbol: SUZ12
Definition:
1. Joined to JAZF1.
2. Zinc finger, C2H2-type domain containing protein.
HIX0013689
  Link to LOCUS view
  Link to H-ANGEL
IPR007087
Zinc finger, C2H2-type [Domain]
CC:0005622
intracellular
MF:0003676
nucleic acid binding
MF:0008270
zinc ion binding
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
36 HIP000032450(55) PPI view Transcript viewRep, Catg. I(6)/6 HIT IDs
UniProt: Q13547, Q5RAG0, Q6IT96, RefSeq: NP_004955, GI: 13128860, CCDS: CCDS360
Shared with Complex 4, Complex 45, Complex 54, Complex 117, Complex 162, Complex 1258.
Gene symbol: HDAC1
Definition:
1. Histone deacetylase 1 (HD1).
2. Histone deacetylase superfamily protein.
HIX0000369
  Link to LOCUS view
  Link to H-ANGEL
IPR000286
Histone deacetylase superfamily [Family]
IPR003084
Histone deacetylase [Family]
BP:0016575
histone deacetylation
CC:0005634
nucleus
MF:0004407
histone deacetylase activity
WoLF PSORT
nuclear, cytosol, mitochondria
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
37 HIP000032659(4) PPI view Transcript viewRep, Catg. I(8), II(5)/13 HIT IDs
UniProt: Q12931, RefSeq: , GI: , CCDS: CCDS10508
Gene symbol: TRAP1
Definition:
1. Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).
2. Heat shock protein Hsp90 family protein.
3. Similar to Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).
HIX0012774
  Link to LOCUS view
  Link to H-ANGEL
IPR001404
Heat shock protein Hsp90 [Family]
IPR003594
ATP-binding region, ATPase-like [Domain]
BP:0006457
protein folding
MF:0005524
ATP binding
MF:0051082
unfolded protein binding
WoLF PSORT
mitochondria, cytosol
Target P
mitochondria
SOSUI
soluble protein
TMHMM
soluble protein
38 HIP000033190(30) PPI view Transcript viewRep, Catg. I(13), II(1), III(29)/43 HIT IDs
UniProt: P68431, P68432, P68433, Q05A97, Q6LBF0, Q6LED0, RefSeq: NP_066298, GI: 4504297, CCDS: CCDS4570, CCDS4573, CCDS4576, CCDS4590, CCDS4596, CCDS4600, CCDS4602, CCDS4627, CCDS4636, CCDS4638
Shared with Complex 46, Complex 158, Complex 406.
Gene symbol: HIST1H2BN, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J
Definition:
1. Histone H3 family protein.
2. Histone H3.1 (H3/a) (H3/b) (H3/c) (H3/d) (H3/f) (H3/h) (H3/i) (H3/j) (H3/k) (H3/l).
3. Histone H3.2 (H3/m) (H3/o).
4. Similar to Histone H3.1 (H3/a) (H3/b) (H3/c) (H3/d) (H3/f) (H3/h) (H3/i) (H3/j) (H3/k) (H3/l).
HIX0001002
  Link to LOCUS view
  Link to H-ANGEL
HIX0003498
  Link to LOCUS view
  Link to H-ANGEL
HIX0005642
  Link to LOCUS view
  Link to H-ANGEL
HIX0005644
  Link to LOCUS view
  Link to H-ANGEL
HIX0025220
  Link to LOCUS view
  Link to H-ANGEL
HIX0032908
  Link to LOCUS view
  Link to H-ANGEL
HIX0032917
  Link to LOCUS view
  Link to H-ANGEL
HIX0032920
  Link to LOCUS view
  Link to H-ANGEL
HIX0032922
  Link to LOCUS view
  Link to H-ANGEL
HIX0032928
  Link to LOCUS view
  Link to H-ANGEL
HIX0056765
  Link to LOCUS view
  Link to H-ANGEL
1kx3_A
1kx3_E
1kx4_A
1kx4_E
1kx5_A
1kx5_E
1u35_A
1u35_E
2cv5_A
2cv5_E
2f8n_A
2f8n_E
2io5_B
2nqb_A
2nqb_E
2pyo_A
2pyo_E
IPR000164
Histone H3 [Family]
IPR007125
Histone core [Domain]
IPR009072
Histone-fold [Domain]
BP:0006334
nucleosome assembly
BP:0007001
chromosome organization and biogenesis (sensu Eukaryota)
CC:0000786
nucleosome
CC:0005634
nucleus
MF:0003677
DNA binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
39 HIP000033428(22) PPI view Transcript viewRep, Catg. I(1)/1 HIT IDs
UniProt: , RefSeq: NP_005325, GI: 98986457, CCDS:
Shared with Complex 54, Complex 106.
Definition:
1. Fibronectin, type III domain containing protein.
2. Host cell factor 1.
HIX0056221
  Link to LOCUS view
  Link to H-ANGEL
IPR003961
Fibronectin, type III [Domain]
IPR006652
Kelch repeat type 1 [Repeat]
IPR008957
Fibronectin, type III-like fold [Domain]
IPR011043
Galactose oxidase, central [Domain]
IPR011498
Kelch repeat type 2 [Repeat]
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
40 HIP000033817(71) PPI view Transcript viewRep, Catg. I(8), II(2)/10 HIT IDs
UniProt: P14373, RefSeq: NP_006501, GI: 5730009, CCDS: CCDS4654
Shared with Complex 55, Complex 535, Complex 1233.
Gene symbol: TRIM27
Definition:
1. Ret finger protein.
2. Similar to Ret finger protein.
3. Zinc finger, RING-type domain containing protein.
HIX0005677
  Link to LOCUS view
  Link to H-ANGEL
HIX0057950
  Link to LOCUS view
  Link to H-ANGEL
HIX0058125
  Link to LOCUS view
  Link to H-ANGEL
IPR000315
Zinc finger, B-box [Domain]
IPR001841
Zinc finger, RING-type [Domain]
IPR001870
B302, (SPRY)-like [Domain]
IPR003877
SPla/RYanodine receptor SPRY [Domain]
IPR003879
Butyrophylin-like [Domain]
IPR006574
SPRY-associated [Domain]
CC:0005622
intracellular
MF:0005515
protein binding
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
41 HIP000033819(1) PPI view Transcript viewCatg. I(1)/1 HIT IDs
UniProt: P14373-2, Q5RJA8, RefSeq: , GI: , CCDS:
Gene symbol: TRIM27
Definition:
1. Ret finger protein.
2. Zinc finger, RING-type domain containing protein.
HIX0057950
  Link to LOCUS view
  Link to H-ANGEL
IPR000315
Zinc finger, B-box [Domain]
IPR001841
Zinc finger, RING-type [Domain]
IPR003879
Butyrophylin-like [Domain]
IPR006574
SPRY-associated [Domain]
CC:0005622
intracellular
MF:0005515
protein binding
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
42 HIP000033911(18) PPI view Transcript viewRep, Catg. I(10)/10 HIT IDs
UniProt: Q16576, Q4R304, Q6FHQ0, Q71UF4, RefSeq: NP_002884, GI: 4506439, CCDS: CCDS14179
Shared with Complex 54, Complex 1258.
Gene symbol: RBBP7
Definition:
1. Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46) (Histone acetyltransferase type B subunit 2) (Nucleosome remodeling factor subunit RBAP46).
2. WD40-like domain containing protein.
HIX0021315
  Link to LOCUS view
  Link to H-ANGEL
IPR001680
WD40 repeat [Repeat]
IPR011046
WD40-like [Domain]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
43 HIP000033970(10) PPI view Transcript viewRep, Catg. I(7), III(2)/9 HIT IDs
UniProt: Q99497, RefSeq: NP_009193, GI: 31543380, CCDS: CCDS93
Shared with Complex 23.
Gene symbol: PARK7
Definition:
1. DJ-1 family protein.
2. Protein DJ-1 (Oncogene DJ1) (Parkinson disease protein 7).
HIX0000097
  Link to LOCUS view
  Link to H-ANGEL
1j42_A
1p5f_A
1pdv_A
1pdw_A
1pdw_B
1pdw_C
1pdw_D
1pdw_E
1pdw_F
1pdw_G
1pdw_H
1pe0_A
1pe0_B
1ps4_A
1q2u_A
1soa_A
1ucf_A
1ucf_B
2or3_A
2or3_B
IPR002818
ThiJ/PfpI [Domain]
IPR006287
DJ-1 [Family]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
44 HIP000035005(22) PPI view Transcript viewRep, Catg. I(1), III(19)/20 HIT IDs
UniProt: P05386, Q56K14, RefSeq: NP_000994, GI: 4506669, CCDS: CCDS10233
Shared with Complex 426.
Gene symbol: RPLP1
Definition:
1. 60S acidic ribosomal protein P1.
2. Ribosomal protein 60S family protein.
HIX0012390
  Link to LOCUS view
  Link to H-ANGEL
IPR001813
Ribosomal protein 60S [Family]
IPR001859
Ribosomal protein P2 [Family]
BP:0006412
translation
BP:0006414
translational elongation
CC:0005622
intracellular
CC:0005840
ribosome
MF:0003735
structural constituent of ribosome
WoLF PSORT

Target P
signal peptide
SOSUI
soluble protein
TMHMM
soluble protein
45 HIP000035968(15) PPI view Transcript viewRep, Catg. I(9), III(1)/10 HIT IDs
UniProt: P55345, Q6FHF0, RefSeq: NP_996845, GI: 46255049, CCDS: CCDS13737
Shared with Complex 49.
Gene symbol: PRMT2
EC No.: EC 2.1.1.-, EC 2.1.1.-
Definition:
1. Protein arginine N-methyltransferase 2 (EC 2.1.1.-).
2. Src homology-3 domain containing protein.
HIX0016196
  Link to LOCUS view
  Link to H-ANGEL
IPR001452
Src homology-3 [Domain]
IPR007848
Methyltransferase small [Domain]
MF:0008168
methyltransferase activity
WoLF PSORT
plasma membrane, cytosol, mitochondria
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
46 HIP000036030(44) PPI view Transcript viewRep, Catg. I(16), II(1), III(2)/19 HIT IDs
UniProt: P11802, Q6FG61, RefSeq: NP_000066, GI: 4502735, CCDS: CCDS8953
Shared with Complex 74, Complex 779.
Gene symbol: CDK4
EC No.: EC 2.7.1.37, EC 2.7.11.22
Definition:
1. Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3).
2. Protein kinase, core domain containing protein.
3. Similar to Cell division protein kinase 4 (EC 2.7.11.22) (Cyclin-dependent kinase 4) (PSK-J3).
HIX0010753
  Link to LOCUS view
  Link to H-ANGEL
IPR000719
Protein kinase, core [Domain]
IPR001245
Tyrosine protein kinase [Domain]
IPR002290
Serine/threonine protein kinase [Domain]
IPR008271
Serine/threonine protein kinase, active site [Active_site]
IPR011009
Protein kinase-like [Domain]
BP:0006468
protein amino acid phosphorylation
MF:0004672
protein kinase activity
MF:0004674
protein serine/threonine kinase activity
MF:0004713
protein-tyrosine kinase activity
MF:0005524
ATP binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
47 HIP000036225(1) PPI view Transcript viewRep, Catg. III(11)/11 HIT IDs
UniProt: Q969S3, RefSeq: NP_219482, GI: 15529978, CCDS: CCDS3886
Gene symbol: ZNF622
Definition:
1. Zinc finger, U1-type domain containing protein.
HIX0004765
  Link to LOCUS view
  Link to H-ANGEL
IPR003604
Zinc finger, U1-type [Domain]
IPR007087
Zinc finger, C2H2-type [Domain]
CC:0005622
intracellular
CC:0005634
nucleus
MF:0003676
nucleic acid binding
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
48 HIP000037399(29) PPI view Transcript viewRep, Catg. I(3), II(1)/4 HIT IDs
UniProt: Q92769, RefSeq: , GI: , CCDS:
Shared with Complex 45, Complex 54, Complex 1258, Complex 1300.
Gene symbol: HDAC2
Definition:
1. Histone deacetylase 2 (HD2).
2. Histone deacetylase superfamily protein.
3. Similar to Histone deacetylase 2.
HIX0006155
  Link to LOCUS view
  Link to H-ANGEL
IPR000286
Histone deacetylase superfamily [Family]
IPR003084
Histone deacetylase [Family]
BP:0016575
histone deacetylation
CC:0005634
nucleus
MF:0004407
histone deacetylase activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
49 HIP000039394(15) PPI view Transcript viewRep, Catg. I(1), IV(1)/2 HIT IDs
UniProt: Q13111, RefSeq: , GI: , CCDS:
Shared with Complex 158.
Gene symbol: CHAF1A
Definition:
1. Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).
2. Conserved hypothetical protein.
HIX0040076
  Link to LOCUS view
  Link to H-ANGEL
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
50 HIP000039637(41) PPI view Transcript viewRep, Catg. I(25), III(3)/28 HIT IDs
UniProt: P62258, P62259, P62260, P62261, P62262, Q4R4J3, Q53XZ5, Q5SS40, Q5ZMT0, RefSeq: NP_006752, GI: 5803225, CCDS: CCDS11001
Shared with Complex 93, Complex 625.
Gene symbol: YWHAE
Definition:
1. 14-3-3 protein epsilon (14-3-3E).
2. 14-3-3 protein family protein.
HIX0013397
  Link to LOCUS view
  Link to H-ANGEL
IPR000308
14-3-3 protein [Family]
MF:0019904
protein domain specific binding
WoLF PSORT
cytosol, nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
51 HIP000039705(19) PPI view Transcript viewRep, Catg. I(1), III(5)/6 HIT IDs
UniProt: P55211, Q53Y70, RefSeq: NP_001220, GI: 14790124, CCDS: CCDS158
Shared with Complex 51, Complex 405.
Gene symbol: CASP9
EC No.: EC 3.4.22.62
Definition:
1. Caspase-9 precursor (EC 3.4.22.62) (CASP-9) (ICE-like apoptotic protease 6) (ICE-LAP6) (Apoptotic protease Mch-6) (Apoptotic protease- activating factor 3) (APAF-3) [Contains: Caspase-9 subunit p35; Caspase-9 subunit p10].
2. Peptidase C14, caspase precursor p45 family protein.
HIX0000153
  Link to LOCUS view
  Link to H-ANGEL
IPR001309
Caspase, p20 subunit [Domain]
IPR001315
Caspase Recruitment [Domain]
IPR002138
Peptidase C14, caspase non-catalytic subunit p10 [Domain]
IPR002398
Peptidase C14, caspase precursor p45 [Family]
IPR011029
DEATH-like [Domain]
IPR011600
Peptidase C14, caspase catalytic [Domain]
BP:0006508
proteolysis
BP:0042981
regulation of apoptosis
CC:0005622
intracellular
MF:0005515
protein binding
MF:0030693
caspase activity
WoLF PSORT
cytosol, nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
52 HIP000040237(45) PPI view Transcript viewCatg. III(1)/1 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Shared with Complex 22, Complex 187, Complex 405, Complex 780, Complex 1028.
Gene symbol: CASP8
EC No.: EC 3.4.22.61
Definition:
1. Peptidase C14, caspase precursor p45 family protein.
HIX0002736
  Link to LOCUS view
  Link to H-ANGEL
IPR001309
Caspase, p20 subunit [Domain]
IPR001875
Death effector [Domain]
IPR002138
Peptidase C14, caspase non-catalytic subunit p10 [Domain]
IPR002398
Peptidase C14, caspase precursor p45 [Family]
IPR011029
DEATH-like [Domain]
IPR011600
Peptidase C14, caspase catalytic [Domain]
BP:0006508
proteolysis
BP:0042981
regulation of apoptosis
MF:0005515
protein binding
MF:0030693
caspase activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
53 HIP000041062(6) PPI view Transcript viewRep, Catg. I(2)/2 HIT IDs
UniProt: Q02548, Q5VVI9, RefSeq: NP_057953, GI: 9951920, CCDS: CCDS6607
Shared with Complex 677.
Gene symbol: PAX5
Definition:
1. Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).
2. Paired box protein, N-terminal domain containing protein.
HIX0034757
  Link to LOCUS view
  Link to H-ANGEL
IPR001523
Paired box protein, N-terminal [Domain]
IPR009057
Homeodomain-like [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
BP:0007275
multicellular organismal development
CC:0005634
nucleus
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
54 HIP000041394(90) PPI view Transcript viewRep, Catg. I(2), III(1)/3 HIT IDs
UniProt: P38398, Q3LRJ6, RefSeq: NP_009227, GI: 6552303, CCDS: CCDS11453
Shared with Complex 4, Complex 42, Complex 157, Complex 328, Complex 621.
Gene symbol: BRCA1
Definition:
1. BRCA1 family protein.
2. Breast and ovarian cancer susceptibility protein splice variant.
3. Breast cancer type 1 susceptibility protein (RING finger protein 53).
HIX0039035
  Link to LOCUS view
  Link to H-ANGEL
IPR001357
BRCT [Domain]
IPR001841
Zinc finger, RING-type [Domain]
IPR002378
Breast cancer type I susceptibility protein [Family]
IPR011364
BRCA1 [Family]
BP:0006281
DNA repair
CC:0005622
intracellular
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0005515
protein binding
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
55 HIP000041437(66) PPI view Transcript viewRep, Catg. I(1), III(3)/4 HIT IDs
UniProt: Q05516, RefSeq: NP_005997, GI: 66932932, CCDS: CCDS8367
Shared with Complex 55, Complex 162, Complex 1072.
Gene symbol: ZBTB16
Definition:
1. Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).
2. Zinc finger, C2H2-type domain containing protein.
HIX0010140
  Link to LOCUS view
  Link to H-ANGEL
IPR000210
BTB/POZ-like [Domain]
IPR007087
Zinc finger, C2H2-type [Domain]
IPR011333
BTB/POZ fold [Domain]
IPR013069
BTB/POZ [Domain]
CC:0005622
intracellular
MF:0003676
nucleic acid binding
MF:0005515
protein binding
MF:0008270
zinc ion binding
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
56 HIP000042326(44) PPI view Transcript viewRep, Catg. I(5), III(4)/9 HIT IDs
UniProt: P20226, Q6IBM6, RefSeq: NP_003185, GI: 4507379, CCDS: CCDS5315
Shared with Complex 4, Complex 126, Complex 251, Complex 267, Complex 548.
Gene symbol: TBP
Definition:
1. TATA-box binding family protein.
2. TATA-box-binding protein (TATA-box factor) (TATA-binding factor) (TATA sequence-binding protein) (Transcription initiation factor TFIID TBP subunit).
HIX0032941
  Link to LOCUS view
  Link to H-ANGEL
IPR000814
TATA-box binding [Family]
IPR012294
Transcription factor TFIID, C-terminal/DNA glycosylase, N-terminal [Domain]
IPR012295
Beta2-adaptin/TATA-box binding, C-terminal [Domain]
BP:0006355
regulation of transcription, DNA-dependent
BP:0006367
transcription initiation from RNA polymerase II promoter
CC:0005634
nucleus
CC:0005669
transcription factor TFIID complex
MF:0003677
DNA binding
MF:0003702
RNA polymerase II transcription factor activity
MF:0005488
binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
57 HIP000043248(2) PPI view Transcript viewRep, Catg. I(3), III(1)/4 HIT IDs
UniProt: Q8WUA4, RefSeq: NP_001512, GI: 78482617, CCDS:
Gene symbol: GTF3C2
Definition:
1. General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).
2. WD40-like domain containing protein.
HIX0001917
  Link to LOCUS view
  Link to H-ANGEL
IPR001680
WD40 repeat [Repeat]
IPR011046
WD40-like [Domain]
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
58 HIP000044120(1) PPI view Transcript viewCatg. I(2)/2 HIT IDs
UniProt: Q9Y3Q5, RefSeq: NP_006609, GI: 57242796, CCDS: CCDS30974
Gene symbol: JARID1B
Definition:
1. PLU-1 protein.
2. Transcription factor jumonji, JmjN domain containing protein.
HIX0001478
  Link to LOCUS view
  Link to H-ANGEL
IPR001606
AT-rich interaction region [Domain]
IPR001965
Zinc finger, PHD-type [Domain]
IPR003347
Transcription factor jumonji/aspartyl beta-hydroxylase [Domain]
IPR003349
Transcription factor jumonji, JmjN [Domain]
IPR004198
Zinc finger, C5HC2-type [Domain]
IPR011011
Zinc finger, FYVE/PHD-type [Domain]
IPR013129
Transcription factor jumonji [Domain]
IPR013637
PLU-1-like [Domain]
CC:0005622
intracellular
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0005515
protein binding
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
59 HIP000044434(15) PPI view Transcript viewCatg. I(3), III(1)/4 HIT IDs
UniProt: P04843, Q68DT1, RefSeq: NP_002941, GI: 4506675, CCDS: CCDS3051
Shared with Complex 515.
Gene symbol: RPN1
EC No.: EC 2.4.1.119
Definition:
1. Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit precursor (EC 2.4.1.119) (Ribophorin I) (RPN-I).
2. Ribophorin I family protein.
HIX0003655
  Link to LOCUS view
  Link to H-ANGEL
IPR007676
Ribophorin I [Family]
BP:0006486
protein amino acid glycosylation
CC:0005783
endoplasmic reticulum
CC:0016021
integral to membrane
MF:0004579
dolichyl-diphosphooligosaccharide-protein glycotransferase activity
WoLF PSORT
endoplasmic, plasma membrane, extracellular
Target P
signal peptide
SOSUI
membrane protein
TMHMM
membrane protein
60 HIP000045022(5) PPI view Transcript viewRep, Catg. I(1), III(8)/9 HIT IDs
UniProt: P05120, RefSeq: NP_002566, GI: 4505595, CCDS: CCDS11989
Gene symbol: SERPINB2
Definition:
1. Plasminogen activator inhibitor 2 precursor (PAI-2) (Placental plasminogen activator inhibitor) (Monocyte Arg-serpin) (Urokinase inhibitor).
2. Protease inhibitor I4, serpin family protein.
HIX0014504
  Link to LOCUS view
  Link to H-ANGEL
IPR000215
Protease inhibitor I4, serpin [Family]
IPR015556
Protease inhibitor I4, serpin, plasminogen activator inhibitor-2 [Family]
MF:0004867
serine-type endopeptidase inhibitor activity
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
61 HIP000045142(37) PPI view Transcript viewRep, Catg. I(26), II(7), III(3)/36 HIT IDs
UniProt: P06748, RefSeq: NP_002511, GI: 10835063, CCDS: CCDS4376
Gene symbol: NPM1
Definition:
1. Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).
2. Nucleoplasmin family protein.
3. Similar to Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38).
HIX0005411
  Link to LOCUS view
  Link to H-ANGEL
IPR004301
Nucleoplasmin [Family]
CC:0005634
nucleus
MF:0003676
nucleic acid binding
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
62 HIP000046378(20) PPI view Transcript viewRep, Catg. I(10)/10 HIT IDs
UniProt: O75832, RefSeq: NP_002805, GI: 4506217, CCDS: CCDS14536
Shared with Complex 30.
Gene symbol: PSMD10
Definition:
1. 26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).
2. Ankyrin repeat containing protein.
HIX0016981
  Link to LOCUS view
  Link to H-ANGEL
1qym_A
1tr4_A
1uoh_A
IPR002110
Ankyrin [Repeat]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
63 HIP000046889(50) PPI view Transcript viewRep, Catg. I(2)/2 HIT IDs
UniProt: P04049, Q5R5M7, RefSeq: NP_002871, GI: 4506401, CCDS: CCDS2612
Shared with Complex 47, Complex 339, Complex 688.
Gene symbol: RAF1
EC No.: EC 2.7.1.37, EC 2.7.11.1
Definition:
1. RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).
2. Raf-like Ras-binding domain containing protein.
HIX0003068
  Link to LOCUS view
  Link to H-ANGEL
IPR000719
Protein kinase, core [Domain]
IPR001245
Tyrosine protein kinase [Domain]
IPR002219
Protein kinase C, phorbol ester/diacylglycerol binding [Domain]
IPR002290
Serine/threonine protein kinase [Domain]
IPR003116
Raf-like Ras-binding [Domain]
IPR008271
Serine/threonine protein kinase, active site [Active_site]
IPR011009
Protein kinase-like [Domain]
BP:0006468
protein amino acid phosphorylation
BP:0007165
signal transduction
BP:0007242
intracellular signaling cascade
MF:0004672
protein kinase activity
MF:0004674
protein serine/threonine kinase activity
MF:0004713
protein-tyrosine kinase activity
MF:0005057
receptor signaling protein activity
MF:0005524
ATP binding
WoLF PSORT
nuclear, cytosol, mitochondria
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
64 HIP000046938(20) PPI view Transcript viewRep, Catg. I(1), III(12)/13 HIT IDs
UniProt: P24385, Q6FI00, RefSeq: NP_444284, GI: 16950655, CCDS: CCDS8191
Shared with Complex 74.
Gene symbol: CCND1
Definition:
1. Cyclin, A/B/D/E family protein.
2. G1/S-specific cyclin-D1 (PRAD1 oncogene) (BCL-1 oncogene).
HIX0009889
  Link to LOCUS view
  Link to H-ANGEL
IPR004367
Cyclin, C-terminal [Domain]
IPR006670
Cyclin [Domain]
IPR006671
Cyclin, N-terminal [Domain]
IPR011028
Cyclin-like [Domain]
IPR013763
Cyclin-related [Domain]
IPR014400
Cyclin, A/B/D/E [Family]
IPR015451
Cyclin D [Family]
BP:0000074
regulation of progression through cell cycle
CC:0005634
nucleus
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
65 HIP000047240(15) PPI view Transcript viewRep, Catg. I(1), III(1)/2 HIT IDs
UniProt: Q00534, RefSeq: NP_001250, GI: 4502741, CCDS: CCDS5628
Shared with Complex 74.
Gene symbol: CDK6
EC No.: EC 2.7.1.37, EC 2.7.11.22
Definition:
1. Cell division protein kinase 6 (EC 2.7.11.22) (Serine/threonine- protein kinase PLSTIRE).
2. Protein kinase, core domain containing protein.
HIX0006844
  Link to LOCUS view
  Link to H-ANGEL
1bi7_A
1bi8_A
1bi8_C
1blx_A
1g3n_A
1g3n_E
IPR000719
Protein kinase, core [Domain]
IPR001245
Tyrosine protein kinase [Domain]
IPR002290
Serine/threonine protein kinase [Domain]
IPR008271
Serine/threonine protein kinase, active site [Active_site]
IPR011009
Protein kinase-like [Domain]
BP:0006468
protein amino acid phosphorylation
MF:0004672
protein kinase activity
MF:0004674
protein serine/threonine kinase activity
MF:0004713
protein-tyrosine kinase activity
MF:0005524
ATP binding
WoLF PSORT
cytosol, nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
66 HIP000047534(8) PPI view Transcript viewRep, Catg. I(1), III(3)/4 HIT IDs
UniProt: P22626, RefSeq: NP_112533, GI: 14043072, CCDS:
Shared with Complex 485.
Definition:
1. Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP B1).
2. RNA recognition motif, RNP-1 domain containing protein.
HIX0006534
  Link to LOCUS view
  Link to H-ANGEL
IPR000504
RNA recognition motif, RNP-1 [Domain]
IPR012677
Nucleotide-binding, alpha-beta plait [Domain]
MF:0000166
nucleotide binding
MF:0003676
nucleic acid binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
67 HIP000047966(11) PPI view Transcript viewRep, Catg. I(1), III(3)/4 HIT IDs
UniProt: P15172, RefSeq: , GI: , CCDS:
Shared with Complex 237.
Gene symbol: MYOD1
Definition:
1. Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).
2. Myogenic basic muscle-specific protein domain containing protein.
HIX0035989
  Link to LOCUS view
  Link to H-ANGEL
IPR001092
Basic helix-loop-helix dimerisation region bHLH [Domain]
IPR002546
Myogenic basic muscle-specific protein [Domain]
IPR011598
Helix-loop-helix DNA-binding [Domain]
BP:0006355
regulation of transcription, DNA-dependent
BP:0007517
muscle development
BP:0045449
regulation of transcription
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0030528
transcription regulator activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
68 HIP000048463(74) PPI view Transcript viewRep, Catg. I(6)/6 HIT IDs
UniProt: P24941, RefSeq: NP_001789, GI: 16936528, CCDS: CCDS8898
Shared with Complex 15, Complex 225, Complex 1100, Complex 1234.
Gene symbol: CDK2
EC No.: EC 2.7.1.37, EC 2.7.11.22
Definition:
1. Cell division protein kinase 2 (EC 2.7.11.22) (p33 protein kinase).
2. Protein kinase, core domain containing protein.
HIX0010710
  Link to LOCUS view
  Link to H-ANGEL
1aq1_A
1b38_A
1b39_A
1buh_A
1ckp_A
1di8_A
1dm2_A
1e1v_A
1e1x_A
1e9h_A
1e9h_C
1f5q_A
1f5q_C
1fin_A
1fin_C
1fq1_B
1fvt_A
1fvv_A
1fvv_C
1g5s_A
1gih_A
1gii_A
1gij_A
1gy3_A
1gy3_C
1gz8_A
1h00_A
1h01_A
1h07_A
1h08_A
1h0v_A
1h0w_A
1h1p_A
1h1p_C
1h1q_A
1h1q_C
1h1r_A
1h1r_C
1h1s_A
1h1s_C
1h24_A
1h24_C
1h25_A
1h25_C
1h26_A
1h26_C
1h27_A
1h27_C
1h28_A
1h28_C
1hck_A
1hcl_A
1jst_A
1jst_C
1jsu_A
1jsv_A
1jvp_P
1ke5_A
1ke6_A
1ke7_A
1ke8_A
1ke9_A
1ogu_A
1ogu_C
1oi9_A
1oi9_C
1oiq_A
1oir_A
1oit_A
1oiu_A
1oiu_C
1oiy_A
1oiy_C
1okv_A
1okv_C
1okw_A
1okw_C
1ol1_A
1ol1_C
1ol2_A
1ol2_C
1p2a_A
1p5e_A
1p5e_C
1pf8_A
1pkd_A
1pkd_C
1pw2_A
1pxi_A
1pxj_A
1pxk_A
1pxl_A
1pxm_A
1pxn_A
1pxo_A
1pxp_A
1pye_A
1qmz_A
1qmz_C
1r78_A
1urc_A
1urc_C
1urw_A
1v1k_A
1vyw_A
1vyw_C
1vyz_A
1w0x_C
1w8c_A
1w98_A
1wcc_A
1y8y_A
1y91_A
1ykr_A
2a0c_X
2a4l_A
2b52_A
2b53_A
2b54_A
2b55_A
2bhe_A
2bhh_A
2bkz_A
2bkz_C
2bpm_A
2bpm_C
2btr_A
2bts_A
2c4g_A
2c4g_C
2c5n_A
2c5n_C
2c5o_A
2c5o_C
2c5p_A
2c5p_C
2c5v_A
2c5v_C
2c5x_A
2c5x_C
2c5y_A
2c68_A
2c69_A
2c6i_A
2c6k_A
2c6l_A
2c6m_A
2c6o_A
2c6t_A
2c6t_C
2cch_A
2cch_C
2cci_A
2cci_C
2cjm_A
2cjm_C
2clx_A
2ds1_A
2duv_A
2exm_A
2fvd_A
2g9x_A
2g9x_C
2i40_A
2i40_C
2iw6_A
2iw6_C
2iw8_A
2iw8_C
2iw9_A
2iw9_C
2j9m_A
2jgz_A
2uue_A
2uue_C
2uzb_A
2uzb_C
2uzd_A
2uzd_C
2uze_A
2uze_C
2uzl_A
2uzl_C
2uzn_A
2uzo_A
2v0d_A
IPR000719
Protein kinase, core [Domain]
IPR001245
Tyrosine protein kinase [Domain]
IPR002290
Serine/threonine protein kinase [Domain]
IPR008271
Serine/threonine protein kinase, active site [Active_site]
IPR011009
Protein kinase-like [Domain]
BP:0006468
protein amino acid phosphorylation
MF:0004672
protein kinase activity
MF:0004674
protein serine/threonine kinase activity
MF:0004713
protein-tyrosine kinase activity
MF:0005524
ATP binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
69 HIP000048686(50) PPI view Transcript viewRep, Catg. I(3), III(2)/5 HIT IDs
UniProt: P42574, RefSeq: NP_116786, GI: 14790119, CCDS: CCDS3836
Shared with Complex 51, Complex 405.
Gene symbol: CASP3
EC No.: EC 3.4.22.56
Definition:
1. Caspase-3 precursor (EC 3.4.22.56) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit].
2. Peptidase C14, caspase precursor p45 family protein.
HIX0004672
  Link to LOCUS view
  Link to H-ANGEL
1cp3_A
1cp3_B
IPR001309
Caspase, p20 subunit [Domain]
IPR002138
Peptidase C14, caspase non-catalytic subunit p10 [Domain]
IPR002398
Peptidase C14, caspase precursor p45 [Family]
IPR011600
Peptidase C14, caspase catalytic [Domain]
IPR015470
Caspase-3-related [Family]
BP:0006508
proteolysis
MF:0030693
caspase activity
WoLF PSORT
cytosol, nuclear, extracellular
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
70 HIP000051023(6) PPI view Transcript viewRep, Catg. I(1)/1 HIT IDs
UniProt: Q13574, RefSeq: , GI: , CCDS:
Shared with Complex 1164.
Gene symbol: DGKZ
EC No.: EC 2.7.1.107
Definition:
1. Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).
2. Protein kinase C, phorbol ester/diacylglycerol binding domain containing protein.
HIX0009600
  Link to LOCUS view
  Link to H-ANGEL
IPR000756
Diacylglycerol kinase accessory region [Domain]
IPR001206
Diacylglycerol kinase, catalytic region [Domain]
IPR002110
Ankyrin [Repeat]
IPR002219
Protein kinase C, phorbol ester/diacylglycerol binding [Domain]
BP:0007205
protein kinase C activation
BP:0007242
intracellular signaling cascade
MF:0004143
diacylglycerol kinase activity
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
71 HIP000051264(7) PPI view Transcript viewCatg. I(2), III(13)/15 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Shared with Complex 101.
Gene symbol: LMNA
Definition:
1. Intermediate filament protein family protein.
2. Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32). Isoform C.
HIX0001147
  Link to LOCUS view
  Link to H-ANGEL
IPR001322
Intermediate filament, C-terminal [Domain]
IPR001664
Intermediate filament protein [Family]
IPR009053
Prefoldin [Domain]
MF:0005198
structural molecule activity
WoLF PSORT
nuclear, cytosol, mitochondria
Target P
mitochondria
SOSUI
soluble protein
TMHMM
soluble protein
72 HIP000051329(11) PPI view Transcript viewRep, Catg. I(1)/1 HIT IDs
UniProt: Q9Y5X4, RefSeq: NP_055064, GI: 7657395, CCDS:
Shared with Complex 54.
Gene symbol: NR2E3
Definition:
1. Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).
2. Steroid hormone receptor family protein.
HIX0026780
  Link to LOCUS view
  Link to H-ANGEL
IPR000003
Retinoid X receptor [Family]
IPR000536
Nuclear hormone receptor, ligand-binding, core [Domain]
IPR001628
Nuclear hormone receptor, DNA-binding [Domain]
IPR001723
Steroid hormone receptor [Family]
IPR008946
Nuclear hormone receptor, ligand-binding [Domain]
BP:0006355
regulation of transcription, DNA-dependent
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0003700
transcription factor activity
MF:0003707
steroid hormone receptor activity
MF:0004879
ligand-dependent nuclear receptor activity
MF:0005496
steroid binding
MF:0008270
zinc ion binding
MF:0016439
tRNA-pseudouridine synthase activity
MF:0043565
sequence-specific DNA binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
73 HIP000051705(45) PPI view Transcript viewRep, Catg. I(7)/7 HIT IDs
UniProt: P10275, RefSeq: , GI: , CCDS:
Shared with Complex 23, Complex 225.
Gene symbol: AR
Definition:
1. Androgen receptor (Dihydrotestosterone receptor).
2. Androgen receptor domain containing protein.
3. Androgen receptor.
HIX0056152
  Link to LOCUS view
  Link to H-ANGEL
IPR000536
Nuclear hormone receptor, ligand-binding, core [Domain]
IPR001103
Androgen receptor [Domain]
IPR001628
Nuclear hormone receptor, DNA-binding [Domain]
IPR008946
Nuclear hormone receptor, ligand-binding [Domain]
BP:0006355
regulation of transcription, DNA-dependent
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0003700
transcription factor activity
MF:0003707
steroid hormone receptor activity
MF:0004882
androgen receptor activity
MF:0005496
steroid binding
MF:0008270
zinc ion binding
MF:0043565
sequence-specific DNA binding
WoLF PSORT

Target P
mitochondria
SOSUI
soluble protein
TMHMM
soluble protein
74 HIP000051755(12) PPI view Transcript viewRep, Catg. I(1)/1 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Shared with Complex 60.
Gene symbol: TOP2A
EC No.: EC 5.99.1.3
Definition:
1. DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).
2. DNA topoisomerase II, eukaryotic-type family protein.
HIX0013797
  Link to LOCUS view
  Link to H-ANGEL
IPR001154
DNA topoisomerase II, eukaryotic-type [Family]
IPR001241
DNA topoisomerase, type IIA, subunit B or N-terminal [Domain]
IPR002205
DNA topoisomerase, type IIA, subunit A or C-terminal [Domain]
IPR003594
ATP-binding region, ATPase-like [Domain]
IPR011558
DNA topoisomerase, type IIA, subunit B, conserved region [Domain]
IPR012542
DTHCT [Domain]
IPR013506
DNA topoisomerase, type IIA, subunit B, region 2 [Domain]
IPR013757
DNA topoisomerase, type IIA, subunit A, alpha-helical [Domain]
IPR013758
DNA topoisomerase, type IIA, subunit A or C-terminal, alpha-beta [Domain]
IPR013759
DNA topoisomerase, type IIA, subunit B or N-terminal, alpha-beta [Domain]
IPR013760
DNA topoisomerase, type IIA, central [Domain]
BP:0006259
DNA metabolic process
BP:0006265
DNA topological change
CC:0005634
nucleus
CC:0005694
chromosome
MF:0003677
DNA binding
MF:0003918
DNA topoisomerase (ATP-hydrolyzing) activity
MF:0005524
ATP binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
75 HIP000052320(24) PPI view Transcript viewCatg. I(1)/1 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Shared with Complex 54, Complex 1042.
Gene symbol: RBL1
Definition:
1. Retinoblastoma-associated protein, A-box domain containing protein.
2. Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (PRB1) (P107).
HIX0015789
  Link to LOCUS view
  Link to H-ANGEL
IPR002719
Retinoblastoma-associated protein, B-box [Domain]
IPR002720
Retinoblastoma-associated protein, A-box [Domain]
IPR006670
Cyclin [Domain]
IPR011028
Cyclin-like [Domain]
IPR013763
Cyclin-related [Domain]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
76 HIP000052859(9) PPI view Transcript viewRep, Catg. I(1), II(1)/2 HIT IDs
UniProt: Q13439, RefSeq: NP_002069, GI: 6715600, CCDS: CCDS2666
Shared with Complex 378.
Gene symbol: GOLGA4
Definition:
1. GRIP domain containing protein.
2. Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).
3. Prefoldin domain containing protein.
4. Similar to Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).
HIX0020830
  Link to LOCUS view
  Link to H-ANGEL
IPR000237
GRIP [Domain]
IPR009053
Prefoldin [Domain]
IPR010978
tRNA-binding arm [Domain]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
77 HIP000053743(1) PPI view Transcript viewCatg. II(2)/2 HIT IDs
UniProt: Q9HCY0, RefSeq: , GI: , CCDS:
Gene symbol: BDP1
Definition:
1. Myb, DNA-binding domain containing protein.
2. Similar to Transcription factor-like nuclear regulator (Fragment).
HIX0004927
  Link to LOCUS view
  Link to H-ANGEL
HIX0057664
  Link to LOCUS view
  Link to H-ANGEL
IPR001005
SANT, DNA-binding [Domain]
IPR009057
Homeodomain-like [Domain]
IPR014778
Myb, DNA-binding [Domain]
CC:0005634
nucleus
MF:0003677
DNA binding
WoLF PSORT

Target P
mitochondria
SOSUI
soluble protein
TMHMM
soluble protein
78 HIP000057323(13) PPI view Transcript viewRep, Catg. I(18), III(4)/22 HIT IDs
UniProt: P09429, Q08IE6, Q4R844, Q5T7C3, Q6YKA4, RefSeq: NP_002119, GI: 4504425, CCDS: CCDS9335
Shared with Complex 88.
Gene symbol: HMGB1
Definition:
1. HMG1/2 (high mobility group) box domain containing protein.
2. High mobility group protein B1 (High mobility group protein 1) (HMG- 1).
HIX0011209
  Link to LOCUS view
  Link to H-ANGEL
IPR000135
High mobility group box HMG1 and HMG2 [Domain]
IPR000910
HMG1/2 (high mobility group) box [Domain]
IPR009071
High mobility group box [Domain]
BP:0006355
regulation of transcription, DNA-dependent
CC:0000785
chromatin
CC:0005634
nucleus
MF:0003677
DNA binding
WoLF PSORT
nuclear
Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
79 HIP000057699(4) PPI view Transcript viewRep, Catg. I(14)/14 HIT IDs
UniProt: P30044, RefSeq: NP_036226, GI: 6912238, CCDS:
Gene symbol: PRDX5
EC No.: EC 1.11.1.15
Definition:
1. Peroxiredoxin-5, mitochondrial precursor (EC 1.11.1.15) (Prx-V) (Peroxisomal antioxidant enzyme) (PLP) (Thioredoxin reductase) (Thioredoxin peroxidase PMP20) (Antioxidant enzyme B166) (AOEB166) (TPx type VI) (Liver tissue 2D-page spot 71B) (Alu corepressor 1).
2. Redoxin domain containing protein.
HIX0021287
  Link to LOCUS view
  Link to H-ANGEL
IPR012335
Thioredoxin fold [Domain]
IPR012336
Thioredoxin-like fold [Domain]
IPR013740
Redoxin [Domain]
MF:0016491
oxidoreductase activity
WoLF PSORT

Target P
mitochondria
SOSUI
soluble protein
TMHMM
soluble protein
80 HIP000058374(43) PPI view Transcript viewRep, Catg. I(1), III(5)/6 HIT IDs
UniProt: Q9UBN6, RefSeq: , GI: , CCDS:
Shared with Complex 282.
Gene symbol: TNFRSF10D
Definition:
1. TNFR/CD27/30/40/95 cysteine-rich region domain containing protein.
2. Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).
HIX0025539
  Link to LOCUS view
  Link to H-ANGEL
IPR001368
TNFR/CD27/30/40/95 cysteine-rich region [Domain]
MF:0004872
receptor activity
WoLF PSORT

Target P
mitochondria
SOSUI
membrane protein
TMHMM
membrane protein
81 HIP000058989(10) PPI view Transcript viewRep, Catg. I(1)/1 HIT IDs
UniProt: P21675, RefSeq: NP_620278, GI: 20357588, CCDS: CCDS35325
Shared with Complex 443, Complex 548.
Gene symbol: TAF1
EC No.: EC 2.7.11.1
Definition:
1. Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).
2. Transcription initiation factor TFIID subunit 1, animal family protein.
HIX0056184
  Link to LOCUS view
  Link to H-ANGEL
IPR001487
Bromodomain [Domain]
IPR009067
TAFII-230 TBP-binding [Domain]
IPR011177
Transcription initiation factor TFIID subunit 1, animal [Family]
BP:0006352
transcription initiation
BP:0006355
regulation of transcription, DNA-dependent
CC:0005669
transcription factor TFIID complex
MF:0003677
DNA binding
WoLF PSORT

Target P
signal peptide
SOSUI
soluble protein
TMHMM
soluble protein
82 HIP000059632(43) PPI view Transcript viewRep, Catg. I(2), II(3)/5 HIT IDs
UniProt: P00519-2, Q17R61, RefSeq: NP_009297, GI: 62362412, CCDS: CCDS35165
Shared with Complex 6, Complex 1020.
Gene symbol: ABL1
EC No.: EC 2.7.1.112, EC 2.7.10.2
Definition:
1. Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1). Isoform IB.
2. Similar to Abelson murine leukemia viral oncogene 1-like protein (Fragment).
3. Similar to Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1). Isoform IB.
4. Src homology-3 domain containing protein.
HIX0008474
  Link to LOCUS view
  Link to H-ANGEL
IPR000719
Protein kinase, core [Domain]
IPR000980
SH2 motif [Domain]
IPR001245
Tyrosine protein kinase [Domain]
IPR001452
Src homology-3 [Domain]
IPR002290
Serine/threonine protein kinase [Domain]
IPR008266
Tyrosine protein kinase, active site [Active_site]
IPR011009
Protein kinase-like [Domain]
IPR015015
F-actin binding [Domain]
BP:0006468
protein amino acid phosphorylation
BP:0007242
intracellular signaling cascade
MF:0004672
protein kinase activity
MF:0004674
protein serine/threonine kinase activity
MF:0004713
protein-tyrosine kinase activity
MF:0005524
ATP binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
83 HIP000060030(42) PPI view Transcript viewCatg. I(10)/10 HIT IDs
UniProt: , RefSeq: NP_000296, GI: 66529294, CCDS: CCDS5640
Shared with Complex 281, Complex 1236.
Gene symbol: PON2
EC No.: EC 3.1.1.2, EC 3.1.8.1
Definition:
1. Paraoxonase 2 isoform 1.
HIX0006862
  Link to LOCUS view
  Link to H-ANGEL
IPR002640
Arylesterase [Family]
IPR008364
Paraoxonase2 [Family]
CC:0005576
extracellular region
MF:0004064
arylesterase activity
WoLF PSORT

Target P
signal peptide
SOSUI
soluble protein
TMHMM
soluble protein
84 HIP000060236(96) PPI view Transcript viewRep, Catg. I(9), II(1), III(1)/11 HIT IDs
UniProt: Q9UET6, RefSeq: NP_036412, GI: 7110661, CCDS: CCDS14294
Shared with Complex 12, Complex 326.
Gene symbol: FTSJ1
EC No.: EC 2.1.1.-, EC 2.1.1.-
Definition:
1. FtsJ homolog 1 isoform a.
2. FtsJ homolog 1 isoform b.
3. Ribosomal RNA methyltransferase J family protein.
4. Similar to FtsJ homolog 1 isoform a.
HIX0016774
  Link to LOCUS view
  Link to H-ANGEL
IPR002877
Ribosomal RNA methyltransferase RrmJ/FtsJ [Domain]
IPR015507
Ribosomal RNA methyltransferase J [Family]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
85 HIP000061336(3) PPI view Transcript viewRep, Catg. I(1), IV(7)/8 HIT IDs
UniProt: Q16533, RefSeq: NP_003073, GI: 4507101, CCDS: CCDS9755
Shared with Complex 1271.
Gene symbol: SNAPC1
Definition:
1. Conserved hypothetical protein.
2. snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (snRNA- activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) (Small nuclear RNA-activating complex polypeptide 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE- binding factor subunit gamma) (PTF subunit gamma).
HIX0020060
  Link to LOCUS view
  Link to H-ANGEL
WoLF PSORT
nuclear, mitochondria, cytosol, Other
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
86 HIP000064420(1) PPI view Transcript viewRep, Catg. I(3), III(3)/6 HIT IDs
UniProt: , RefSeq: NP_006277, GI: 5454112, CCDS:
Definition:
1. Transcription factor DP family protein.
2. Transcription factor Dp-2 (E2F dimerization partner 2).
HIX0003733
  Link to LOCUS view
  Link to H-ANGEL
HIX0076112
  Link to LOCUS view
  Link to H-ANGEL
IPR003316
Transcription factor E2F/dimerisation partner (TDP) [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
IPR014889
Transcription factor DP, C-terminal [Domain]
IPR015648
Transcription factor DP [Family]
BP:0000074
regulation of progression through cell cycle
BP:0006355
regulation of transcription, DNA-dependent
CC:0005667
transcription factor complex
MF:0003700
transcription factor activity
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
87 HIP000065442(25) PPI view Transcript viewRep, Catg. I(1), II(1), III(1)/3 HIT IDs
UniProt: Q96LZ4, RefSeq: , GI: , CCDS:
Shared with Complex 300.
Definition:
1. Similar to Testis expressed sequence 11 isoform 2.
2. Testis expressed sequence 11 isoform 2.
3. Tetratricopeptide region domain containing protein.
HIX0022351
  Link to LOCUS view
  Link to H-ANGEL
IPR011990
Tetratricopeptide-like helical [Domain]
IPR013026
Tetratricopeptide region [Domain]
IPR013105
Tetratricopeptide TPR_2 [Repeat]
MF:0005488
binding
WoLF PSORT
extracellular, cytosol, nuclear, Other
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
88 HIP000066020(3) PPI view Transcript viewRep, Catg. I(1)/1 HIT IDs
UniProt: P29374, RefSeq: , GI: , CCDS:
Gene symbol: ARID4A
Definition:
1. AT-rich interaction region domain containing protein.
2. AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).
HIX0037655
  Link to LOCUS view
  Link to H-ANGEL
IPR000953
Chromo [Domain]
IPR001606
AT-rich interaction region [Domain]
IPR002999
Tudor [Domain]
IPR012603
RBB1NT [Domain]
BP:0006333
chromatin assembly or disassembly
CC:0000785
chromatin
CC:0005622
intracellular
CC:0005634
nucleus
MF:0003676
nucleic acid binding
MF:0003677
DNA binding
MF:0003682
chromatin binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
89 HIP000066894(24) PPI view Transcript viewRep, Catg. I(1), III(5)/6 HIT IDs
UniProt: , RefSeq: NP_001871, GI: 22538422, CCDS: CCDS2262
Shared with Complex 7.
Gene symbol: ATF2
Definition:
1. Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).
2. Zinc finger, C2H2-type domain containing protein.
HIX0002611
  Link to LOCUS view
  Link to H-ANGEL
IPR004827
Basic-leucine zipper (bZIP) transcription factor [Domain]
IPR007087
Zinc finger, C2H2-type [Domain]
IPR011616
bZIP transcription factor, bZIP_1 [Domain]
BP:0006355
regulation of transcription, DNA-dependent
CC:0005622
intracellular
CC:0005634
nucleus
MF:0003676
nucleic acid binding
MF:0003700
transcription factor activity
MF:0008270
zinc ion binding
MF:0043565
sequence-specific DNA binding
MF:0046983
protein dimerization activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
90 HIP000068693(10) PPI view Transcript viewRep, Catg. I(4)/4 HIT IDs
UniProt: Q96SH1, RefSeq: , GI: , CCDS:
Shared with Complex 606, Complex 943.
Gene symbol: TFAP2A
Definition:
1. Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).
2. Transcription factor AP-2 alpha isoform b.
3. Transcription factor AP-2 family protein.
HIX0025068
  Link to LOCUS view
  Link to H-ANGEL
IPR004979
Transcription factor AP-2 [Family]
IPR008121
Transcription factor AP-2 alpha, N-terminal [Domain]
IPR013854
Transcription factor AP-2, C-terminal [Domain]
BP:0006355
regulation of transcription, DNA-dependent
CC:0005634
nucleus
MF:0003700
transcription factor activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
91 HIP000069595(18) PPI view Transcript viewRep, Catg. I(3)/3 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Shared with Complex 54.
Gene symbol: SIN3A
Definition:
1. Histone deacetylase interacting domain containing protein.
2. Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).
HIX0012443
  Link to LOCUS view
  Link to H-ANGEL
IPR003822
Paired amphipathic helix [Repeat]
IPR013194
Histone deacetylase interacting [Domain]
BP:0006355
regulation of transcription, DNA-dependent
CC:0005634
nucleus
WoLF PSORT
nuclear, cytoskeleton
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
92 HIP000069922(1) PPI view Transcript viewCatg. I(1)/1 HIT IDs
UniProt: Q92851-2, RefSeq: , GI: , CCDS:
Gene symbol: CASP10
EC No.: EC 3.4.22.63
Definition:
1. Caspase-10 precursor (EC 3.4.22.63) (CASP-10) (ICE-like apoptotic protease 4) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) [Contains: Caspase-10 subunit p23/17; Caspase-10 subunit p12]. Isoform B.
2. Peptidase C14, caspase precursor p45 family protein.
HIX0023926
  Link to LOCUS view
  Link to H-ANGEL
IPR001309
Caspase, p20 subunit [Domain]
IPR001875
Death effector [Domain]
IPR002138
Peptidase C14, caspase non-catalytic subunit p10 [Domain]
IPR002398
Peptidase C14, caspase precursor p45 [Family]
IPR011029
DEATH-like [Domain]
IPR011600
Peptidase C14, caspase catalytic [Domain]
BP:0006508
proteolysis
BP:0042981
regulation of apoptosis
MF:0005515
protein binding
MF:0030693
caspase activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
93 HIP000070443(5) PPI view Transcript viewRep, Catg. I(1), III(1)/2 HIT IDs
UniProt: Q13112, RefSeq: NP_005432, GI: 4885105, CCDS: CCDS13644
Shared with Complex 158.
Gene symbol: CHAF1B
Definition:
1. Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).
2. G-protein, beta subunit family protein.
HIX0016103
  Link to LOCUS view
  Link to H-ANGEL
IPR001632
G-protein, beta subunit [Family]
IPR001680
WD40 repeat [Repeat]
IPR011046
WD40-like [Domain]
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
94 HIP000072405(13) PPI view Transcript viewRep, Catg. I(1), III(5)/6 HIT IDs
UniProt: P20248, RefSeq: NP_001228, GI: 4502613, CCDS:
Shared with Complex 15, Complex 1100.
Gene symbol: CCNA2
Definition:
1. Cyclin, A/B/D/E family protein.
2. Cyclin-A2 (Cyclin-A).
HIX0031483
  Link to LOCUS view
  Link to H-ANGEL
IPR004367
Cyclin, C-terminal [Domain]
IPR006670
Cyclin [Domain]
IPR006671
Cyclin, N-terminal [Domain]
IPR011028
Cyclin-like [Domain]
IPR013763
Cyclin-related [Domain]
IPR014400
Cyclin, A/B/D/E [Family]
IPR015453
G2/mitotic-specific cyclin A [Family]
BP:0000074
regulation of progression through cell cycle
CC:0005634
nucleus
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
95 HIP000075056(6) PPI view Transcript viewRep, Catg. I(5)/5 HIT IDs
UniProt: P17947, RefSeq: NP_003111, GI: 124028517, CCDS:
Shared with Complex 1215.
Gene symbol: SPI1
Definition:
1. Ets domain containing protein.
2. Transcription factor PU.1 (31 kDa transforming protein).
HIX0035922
  Link to LOCUS view
  Link to H-ANGEL
IPR000418
Ets [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
BP:0006355
regulation of transcription, DNA-dependent
CC:0005634
nucleus
MF:0003700
transcription factor activity
MF:0043565
sequence-specific DNA binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
96 HIP000075139(8) PPI view Transcript viewRep, Catg. I(1), III(2)/3 HIT IDs
UniProt: Q14209, RefSeq: NP_004082, GI: 4758226, CCDS: CCDS236
Shared with Complex 632.
Gene symbol: E2F2
Definition:
1. E2F Family family protein.
2. Transcription factor E2F2 (E2F-2).
HIX0017689
  Link to LOCUS view
  Link to H-ANGEL
IPR003316
Transcription factor E2F/dimerisation partner (TDP) [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
IPR015633
E2F Family [Family]
BP:0000074
regulation of progression through cell cycle
BP:0006355
regulation of transcription, DNA-dependent
CC:0005667
transcription factor complex
MF:0003700
transcription factor activity
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
97 HIP000077000(285) PPI view Transcript viewRep, Catg. I(2), III(48)/50 HIT IDs
UniProt: P30460, Q5SS57, RefSeq: , GI: , CCDS:
Shared with Complex 10, Complex 131, Complex 216, Complex 252, Complex 281, Complex 481, Complex 989, Complex 1008, Complex 1022, Complex 1147, Complex 1178, Complex 1200, Complex 1218, Complex 1314.
Gene symbol: HLA-B
Definition:
1. HLA class I histocompatibility antigen, B-7 alpha chain precursor (MHC class I antigen B*7).
2. HLA class I histocompatibility antigen, B-8 alpha chain precursor (MHC class I antigen B*8).
3. MHC class I, alpha chain, alpha1 and alpha2 domain containing protein.
HIX0078239
  Link to LOCUS view
  Link to H-ANGEL
HIX0078437
  Link to LOCUS view
  Link to H-ANGEL
IPR001039
MHC class I, alpha chain, alpha1 and alpha2 [Domain]
IPR003006
Immunoglobulin/major histocompatibility complex motif [Domain]
IPR003597
Immunoglobulin C1-set [Domain]
IPR007110
Immunoglobulin-like [Domain]
IPR010579
MHC class I, alpha chain, C-terminal [Domain]
IPR011161
MHC class I-like antigen recognition [Domain]
IPR011162
MHC classes I and II-like antigen recognition [Domain]
IPR013783
Immunoglobulin-like fold [Domain]
BP:0006955
immune response
BP:0019882
antigen processing and presentation
CC:0016020
membrane
CC:0042612
MHC class I protein complex
WoLF PSORT

Target P
signal peptide
SOSUI
membrane protein
TMHMM
membrane protein
98 HIP000077614(6) PPI view Transcript viewRep, Catg. I(1), III(5)/6 HIT IDs
UniProt: P04080, P60575, P60576, Q76LA0, Q76LA1, RefSeq: NP_000091, GI: 4503117, CCDS: CCDS13701
Gene symbol: CSTB
Definition:
1. Cystatin-B (Stefin-B) (Liver thiol proteinase inhibitor) (CPI-B).
2. Proteinase inhibitor I25A, stefin A family protein.
HIX0016156
  Link to LOCUS view
  Link to H-ANGEL
IPR000010
Proteinase inhibitor I25, cystatin [Domain]
IPR001713
Proteinase inhibitor I25A, stefin A [Family]
CC:0005622
intracellular
MF:0004866
endopeptidase inhibitor activity
MF:0004869
cysteine protease inhibitor activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
99 HIP000079851(6) PPI view Transcript viewCatg. I(2)/2 HIT IDs
UniProt: P17480, RefSeq: NP_055048, GI: 7657671, CCDS: CCDS11480
Shared with Complex 672.
Gene symbol: UBTF
Definition:
1. HMG1/2 (high mobility group) box domain containing protein.
2. Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).
HIX0027134
  Link to LOCUS view
  Link to H-ANGEL
IPR000910
HMG1/2 (high mobility group) box [Domain]
IPR009071
High mobility group box [Domain]
BP:0006355
regulation of transcription, DNA-dependent
MF:0003677
DNA binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
100 HIP000080260(17) PPI view Transcript viewRep, Catg. I(3)/3 HIT IDs
UniProt: Q99708, RefSeq: NP_976036, GI: 4506441, CCDS: CCDS11875
Shared with Complex 157, Complex 328.
Gene symbol: RBBP8
Definition:
1. Conserved hypothetical protein.
2. Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).
HIX0014362
  Link to LOCUS view
  Link to H-ANGEL
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
101 HIP000081272(1) PPI view Transcript viewRep, Catg. III(1)/1 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Gene symbol: PRDM2
Definition:
1. Predicted retinoblastoma binding protein (RIZ) family protein.
2. SET domain containing protein.
HIX0023570
  Link to LOCUS view
  Link to H-ANGEL
IPR001214
SET [Domain]
IPR007087
Zinc finger, C2H2-type [Domain]
IPR009170
Predicted retinoblastoma binding protein (RIZ) [Family]
BP:0045449
regulation of transcription
CC:0005622
intracellular
CC:0005634
nucleus
MF:0003676
nucleic acid binding
MF:0003677
DNA binding
MF:0008270
zinc ion binding
MF:0030528
transcription regulator activity
MF:0046872
metal ion binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
102 HIP000081826(7) PPI view Transcript viewRep, Catg. I(3), III(1)/4 HIT IDs
UniProt: P35869, RefSeq: NP_001612, GI: 4502003, CCDS: CCDS5366
Shared with Complex 192.
Gene symbol: AHR
Definition:
1. Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).
2. Basic helix-loop-helix dimerisation region bHLH domain containing protein.
HIX0033619
  Link to LOCUS view
  Link to H-ANGEL
IPR000014
PAS [Domain]
IPR001092
Basic helix-loop-helix dimerisation region bHLH [Domain]
IPR001610
PAC motif [Repeat]
IPR011598
Helix-loop-helix DNA-binding [Domain]
IPR013655
PAS fold-3 [Domain]
IPR013767
PAS fold [Domain]
BP:0006355
regulation of transcription, DNA-dependent
BP:0007165
signal transduction
BP:0045449
regulation of transcription
CC:0005634
nucleus
MF:0004871
signal transducer activity
MF:0030528
transcription regulator activity
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
103 HIP000082755(15) PPI view Transcript viewCatg. I(2), II(1)/3 HIT IDs
UniProt: P26358, RefSeq: NP_001370, GI: 4503351, CCDS: CCDS12228
Shared with Complex 84.
Gene symbol: DNMT1
EC No.: EC 2.1.1.37
Definition:
1. DMAP1-binding domain containing protein.
2. DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).
3. DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI). Isoform 2.
4. Similar to DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).
HIX0027457
  Link to LOCUS view
  Link to H-ANGEL
IPR001025
Bromo adjacent region [Domain]
IPR001525
C-5 cytosine-specific DNA methylase [Domain]
IPR002857
Zinc finger, CXXC-type [Domain]
IPR010506
DMAP1-binding [Domain]
BP:0006306
DNA methylation
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0008134
transcription factor binding
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
104 HIP000083181(8) PPI view Transcript viewCatg. II(1)/1 HIT IDs
UniProt: P42166, RefSeq: NP_003267, GI: 4507555, CCDS: CCDS9064
Gene symbol: TMPO
Definition:
1. Lamino-associated polypeptide 2/emerin domain containing protein.
2. Similar to Lamina-associated polypeptide 2 isoform alpha (Thymopoietin isoform alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) [Contains: Thymopoietin (TP) (Splenin); Thymopentin (TP5)].
HIX0026336
  Link to LOCUS view
  Link to H-ANGEL
IPR003887
Lamino-associated polypeptide 2/emerin [Domain]
IPR011015
LEM-like fold [Domain]
IPR013142
LEM-like region [Domain]
IPR013146
Thymopoietin LEM [Domain]
CC:0005635
nuclear envelope
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
105 HIP000084384(2) PPI view Transcript viewRep, Catg. I(1), IV(8)/9 HIT IDs
UniProt: Q13442, RefSeq: NP_055706, GI: 7657441, CCDS: CCDS5662
Gene symbol: PDAP1
Definition:
1. 28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1).
2. Conserved hypothetical protein.
HIX0006889
  Link to LOCUS view
  Link to H-ANGEL
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
106 HIP000085983(5) PPI view Transcript viewRep, Catg. I(17)/17 HIT IDs
UniProt: P49458, RefSeq: XP_943209, GI: 89033521, CCDS: CCDS1546
Gene symbol: SRP9
Definition:
1. Signal recognition particle 9 kDa family protein.
2. Signal recognition particle 9 kDa protein (SRP9).
HIX0001635
  Link to LOCUS view
  Link to H-ANGEL
1e8o_A
1e8o_C
1e8s_A
1ry1_C
IPR008832
Signal recognition particle 9 kDa [Family]
IPR009018
Signal recognition particle, 9 kDa and 14 kDa protein [Family]
BP:0006605
protein targeting
BP:0045900
negative regulation of translational elongation
CC:0005786
signal recognition particle, endoplasmic reticulum targeting
MF:0003723
RNA binding
WoLF PSORT
cytosol, extracellular, nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
107 HIP000086308(207) PPI view Transcript viewRep, Catg. I(1)/1 HIT IDs
UniProt: P40337, RefSeq: NP_000542, GI: 4507891, CCDS: CCDS2597
Shared with Complex 40, Complex 168, Complex 180, Complex 231, Complex 558, Complex 922, Complex 1085, Complex 1152, Complex 1155, Complex 1234.
Gene symbol: VHL
Definition:
1. Tumor suppressor protein, von Hippel-Lindau disease family protein.
2. Von Hippel-Lindau disease tumor suppressor (pVHL) (G7 protein).
HIX0030712
  Link to LOCUS view
  Link to H-ANGEL
IPR002714
Tumor suppressor protein, von Hippel-Lindau disease [Family]
BP:0016567
protein ubiquitination
CC:0005634
nucleus
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
108 HIP000089899(22) PPI view Transcript viewRep, Catg. I(1), III(6)/7 HIT IDs
UniProt: P17676, RefSeq: NP_005185, GI: 28872796, CCDS: CCDS13429
Shared with Complex 7.
Gene symbol: CEBPB
Definition:
1. Basic leucine zipper domain containing protein.
2. CCAAT/enhancer-binding protein beta (C/EBP beta) (Nuclear factor NF- IL6) (Transcription factor 5).
HIX0015909
  Link to LOCUS view
  Link to H-ANGEL
IPR004827
Basic-leucine zipper (bZIP) transcription factor [Domain]
IPR011700
Basic leucine zipper [Domain]
BP:0006355
regulation of transcription, DNA-dependent
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0003700
transcription factor activity
MF:0043565
sequence-specific DNA binding
MF:0046983
protein dimerization activity
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
109 HIP000092250(3) PPI view Transcript viewCatg.
UniProt: Q13950-2, RefSeq: NP_004339, GI: 66934969, CCDS: CCDS4913
Shared with Complex 1254.
Definition:
1. Acute myeloid leukemia 1 protein (AML 1)/Runt family protein.
WoLF PSORT

Target P

SOSUI

TMHMM
110 HIP000092348(7) PPI view Transcript viewRep, Catg. I(1)/1 HIT IDs
UniProt: O00716, RefSeq: NP_001940, GI: 4503433, CCDS: CCDS4545
Shared with Complex 632.
Gene symbol: E2F3
Definition:
1. E2F Family family protein.
2. Transcription factor E2F3 (E2F-3).
HIX0005612
  Link to LOCUS view
  Link to H-ANGEL
IPR003316
Transcription factor E2F/dimerisation partner (TDP) [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
IPR015633
E2F Family [Family]
BP:0000074
regulation of progression through cell cycle
BP:0006355
regulation of transcription, DNA-dependent
CC:0005667
transcription factor complex
MF:0003700
transcription factor activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
111 HIP000094201(5) PPI view Transcript viewCatg. I(2)/2 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Shared with Complex 1083.
Gene symbol: L3MBTL
Definition:
1. Lethal(3)malignant brain tumor-like protein (L(3)mbt-like) (L(3)mbt protein homolog) (H-l(3)mbt protein) (H-L(3)MBT) (L3MBTL1).
2. Sterile alpha motif homology domain containing protein.
HIX0015827
  Link to LOCUS view
  Link to H-ANGEL
IPR002515
Zinc finger, C2HC-type [Repeat]
IPR004092
Mbt repeat [Repeat]
IPR010993
Sterile alpha motif homology [Domain]
IPR013761
Sterile alpha motif-type [Domain]
BP:0006355
regulation of transcription, DNA-dependent
BP:0045449
regulation of transcription
CC:0005634
nucleus
MF:0003700
transcription factor activity
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
112 HIP000095420(12) PPI view Transcript viewRep, Catg. I(9), III(2)/11 HIT IDs
UniProt: P05387, Q6FG96, RefSeq: NP_000995, GI: 4506671, CCDS: CCDS7717
Gene symbol: RPLP2
Definition:
1. 60S acidic ribosomal protein P2 (Renal carcinoma antigen NY-REN-44).
2. Ribosomal protein 60S family protein.
HIX0018031
  Link to LOCUS view
  Link to H-ANGEL
IPR001813
Ribosomal protein 60S [Family]
BP:0006414
translational elongation
CC:0005622
intracellular
CC:0005840
ribosome
MF:0003735
structural constituent of ribosome
WoLF PSORT
mitochondria, cytosol, extracellular, Other
Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
113 HIP000096206(10) PPI view Transcript viewRep, Catg. I(1), III(10)/11 HIT IDs
UniProt: P21266, Q6FGJ9, RefSeq: NP_000840, GI: 23065552, CCDS: CCDS812
Shared with Complex 803.
Gene symbol: GSTM3
EC No.: EC 2.5.1.18
Definition:
1. Glutathione S-transferase Mu 3 (EC 2.5.1.18) (GSTM3-3) (GST class-mu 3) (hGSTM3-3).
2. Glutathione S-transferase, Mu class family protein.
HIX0000858
  Link to LOCUS view
  Link to H-ANGEL
3gtu_B
3gtu_D
IPR003081
Glutathione S-transferase, Mu class [Family]
IPR004045
Glutathione S-transferase, N-terminal [Domain]
IPR004046
Glutathione S-transferase, C-terminal [Domain]
IPR010987
Glutathione S-transferase, C-terminal-like [Domain]
IPR012335
Thioredoxin fold [Domain]
IPR012336
Thioredoxin-like fold [Domain]
BP:0008152
metabolic process
MF:0004364
glutathione transferase activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
114 HIP000096717(45) PPI view Transcript viewRep, Catg. I(1), II(1), III(1)/3 HIT IDs
UniProt: P08047, RefSeq: NP_612482, GI: 38372901, CCDS: CCDS8857
Shared with Complex 4, Complex 259, Complex 632, Complex 1098.
Gene symbol: SP1
Definition:
1. Similar to Transcription factor Sp1 (Fragment).
2. Transcription factor Sp1.
3. Zinc finger, C2H2-type domain containing protein.
HIX0010670
  Link to LOCUS view
  Link to H-ANGEL
IPR007087
Zinc finger, C2H2-type [Domain]
CC:0005622
intracellular
MF:0003676
nucleic acid binding
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
115 HIP000096766(1) PPI view Transcript viewCatg. I(1), II(3)/4 HIT IDs
UniProt: Q07161, RefSeq: NP_001008709, GI: 56790945, CCDS: CCDS31618
EC No.: EC 3.1.3.16
Definition:
1. Metallophosphoesterase domain containing protein.
2. Protein phosphatase 1, catalytic subunit, alpha isoform 3.
3. Similar to Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (EC 3.1.3.16) (PP-1A).
HIX0009860
  Link to LOCUS view
  Link to H-ANGEL
IPR004843
Metallophosphoesterase [Domain]
IPR006186
Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase [Domain]
MF:0016787
hydrolase activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
116 HIP000096767(62) PPI view Transcript viewRep, Catg. I(21), II(2), III(1)/24 HIT IDs
UniProt: P62136, P62138, P62139, Q2EHH8, Q3T0E7, RefSeq: NP_002699, GI: 4506003, CCDS: CCDS8160
Shared with Complex 274.
Gene symbol: PPP1CA
EC No.: EC 3.1.3.16
Definition:
1. Metallophosphoesterase domain containing protein.
2. Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (EC 3.1.3.16) (PP-1A).
3. Similar to Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (EC 3.1.3.16) (PP-1A).
HIX0009860
  Link to LOCUS view
  Link to H-ANGEL
IPR004843
Metallophosphoesterase [Domain]
IPR006186
Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase [Domain]
MF:0016787
hydrolase activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
117 HIP000096784(16) PPI view Transcript viewRep, Catg. I(4)/4 HIT IDs
UniProt: P45984, RefSeq: NP_002743, GI: 21237736, CCDS: CCDS4453
Shared with Complex 353, Complex 682.
Gene symbol: MAPK9
EC No.: EC 2.7.1.37, EC 2.7.11.24
Definition:
1. MAP kinase family protein.
2. Mitogen-activated protein kinase 9 (EC 2.7.11.24) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55).
HIX0005495
  Link to LOCUS view
  Link to H-ANGEL
IPR000719
Protein kinase, core [Domain]
IPR001245
Tyrosine protein kinase [Domain]
IPR002290
Serine/threonine protein kinase [Domain]
IPR003527
MAP kinase [Family]
IPR008271
Serine/threonine protein kinase, active site [Active_site]
IPR008351
JNK MAP kinase [Family]
IPR011009
Protein kinase-like [Domain]
BP:0006468
protein amino acid phosphorylation
MF:0004672
protein kinase activity
MF:0004674
protein serine/threonine kinase activity
MF:0004707
MAP kinase activity
MF:0004713
protein-tyrosine kinase activity
MF:0005524
ATP binding
WoLF PSORT
plasma membrane, cytosol, mitochondria
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
118 HIP000096938(19) PPI view Transcript viewRep, Catg. I(1), III(2)/3 HIT IDs
UniProt: Q92831, RefSeq: NP_003875, GI: 40805843, CCDS: CCDS2634
Shared with Complex 58.
Gene symbol: PCAF
EC No.: EC 2.3.1.48
Definition:
1. Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).
2. PCAF, N-terminal domain containing protein.
HIX0003121
  Link to LOCUS view
  Link to H-ANGEL
IPR000182
GCN5-related N-acetyltransferase [Domain]
IPR001487
Bromodomain [Domain]
IPR009464
PCAF, N-terminal [Domain]
BP:0008152
metabolic process
MF:0008080
N-acetyltransferase activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
119 HIP000097238(7) PPI view Transcript viewCatg. IV(35)/35 HIT IDs
UniProt: Q9Y6B2, RefSeq: NP_055150, GI: 7656938, CCDS:
Shared with Complex 264.
Gene symbol: EID1
Definition:
1. Conserved hypothetical protein.
HIX0012222
  Link to LOCUS view
  Link to H-ANGEL
WoLF PSORT
nuclear, cytosol, extracellular
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
120 HIP000097281(43) PPI view Transcript viewRep, Catg. I(14), III(2)/16 HIT IDs
UniProt: P38936, Q6FI05, RefSeq: NP_510867, GI: 17978495, CCDS: CCDS4824
Shared with Complex 15, Complex 74, Complex 955, Complex 1100.
Gene symbol: CDKN1A
Definition:
1. Cyclin-dependent kinase inhibitor 1 (p21) (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6).
2. Cyclin-dependent kinase inhibitor family protein.
HIX0005824
  Link to LOCUS view
  Link to H-ANGEL
IPR003175
Cyclin-dependent kinase inhibitor [Family]
BP:0007050
cell cycle arrest
CC:0005634
nucleus
MF:0004861
cyclin-dependent protein kinase inhibitor activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
121 HIP000097977(32) PPI view Transcript viewRep, Catg. I(26)/26 HIT IDs
UniProt: Q9UQ80, RefSeq: NP_006182, GI: 124494254, CCDS: CCDS8902
Shared with Complex 250.
Gene symbol: PA2G4
Definition:
1. Proliferation-associated protein 1 family protein.
2. Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1).
HIX0022101
  Link to LOCUS view
  Link to H-ANGEL
HIX0080947
  Link to LOCUS view
  Link to H-ANGEL
2q8k_A
IPR000994
Peptidase M24, catalytic core [Domain]
IPR002468
Peptidase M24A, methionine aminopeptidase, subfamily 2 [Family]
IPR004545
Proliferation-associated protein 1 [Family]
BP:0006508
proteolysis
MF:0004239
methionyl aminopeptidase activity
MF:0008235
metalloexopeptidase activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
122 HIP000098402(36) PPI view Transcript viewRep, Catg. I(18), III(28)/46 HIT IDs
UniProt: P62794, P62795, P62796, P62797, P62798, P62799, P62800, P62801, P62802, P62803, P62804, P62805, P62806, Q28DR4, Q45RT4, Q4PM69, Q4R362, Q4SKJ2, Q5DET3, Q5RCS7, Q5T006, Q6DRA9, Q6WV72, Q6WV73, Q6WV90, Q7K8C0, Q7KQD1, RefSeq: NP_778224, GI: 77539758, CCDS: CCDS30847, CCDS30851, CCDS4571, CCDS4572, CCDS4583, CCDS4589, CCDS4593, CCDS4598, CCDS4604, CCDS4620, CCDS4630, CCDS4631, CCDS4637, CCDS8665
Shared with Complex 46, Complex 548, Complex 1083.
Gene symbol: HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4
Definition:
1. Histone H4 family protein.
2. Histone H4.
HIX0001001
  Link to LOCUS view
  Link to H-ANGEL
HIX0003499
  Link to LOCUS view
  Link to H-ANGEL
HIX0005643
  Link to LOCUS view
  Link to H-ANGEL
HIX0005658
  Link to LOCUS view
  Link to H-ANGEL
HIX0019648
  Link to LOCUS view
  Link to H-ANGEL
HIX0021127
  Link to LOCUS view
  Link to H-ANGEL
HIX0025222
  Link to LOCUS view
  Link to H-ANGEL
HIX0032918
  Link to LOCUS view
  Link to H-ANGEL
HIX0032931
  Link to LOCUS view
  Link to H-ANGEL
HIX0032933
  Link to LOCUS view
  Link to H-ANGEL
HIX0032934
  Link to LOCUS view
  Link to H-ANGEL
HIX0033000
  Link to LOCUS view
  Link to H-ANGEL
HIX0033460
  Link to LOCUS view
  Link to H-ANGEL
HIX0056766
  Link to LOCUS view
  Link to H-ANGEL
IPR001951
Histone H4 [Family]
IPR007125
Histone core [Domain]
IPR009072
Histone-fold [Domain]
BP:0006334
nucleosome assembly
BP:0007001
chromosome organization and biogenesis (sensu Eukaryota)
CC:0000786
nucleosome
CC:0005634
nucleus
MF:0003677
DNA binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
123 HIP000098404(13) PPI view Transcript viewRep, Catg. I(19), III(39)/58 HIT IDs
UniProt: P0C169, Q93077, RefSeq: NP_003503, GI: 4504245, CCDS: CCDS4585
Shared with Complex 46.
Gene symbol: HIST1H2AC
Definition:
1. H2A histone family, member J isoform 2.
2. Histone H2A family protein.
3. Histone H2A type 1 (H2A.1).
4. Histone H2A type 1-C.
5. Histone H2A type 1-E (H2A.2) (H2A/m).
6. Histone H2A type 1-H.
7. Histone H2A type 1-J.
8. Histone H2A type 2-A (H2A.2).
9. Histone H2A type 2-C (H2A-GL101) (H2A/r).
10. Histone H2A type 3.
HIX0001003
  Link to LOCUS view
  Link to H-ANGEL
HIX0001670
  Link to LOCUS view
  Link to H-ANGEL
HIX0003498
  Link to LOCUS view
  Link to H-ANGEL
HIX0005639
  Link to LOCUS view
  Link to H-ANGEL
HIX0005642
  Link to LOCUS view
  Link to H-ANGEL
HIX0005657
  Link to LOCUS view
  Link to H-ANGEL
HIX0010455
  Link to LOCUS view
  Link to H-ANGEL
HIX0020326
  Link to LOCUS view
  Link to H-ANGEL
HIX0025206
  Link to LOCUS view
  Link to H-ANGEL
HIX0028771
  Link to LOCUS view
  Link to H-ANGEL
HIX0032914
  Link to LOCUS view
  Link to H-ANGEL
HIX0032932
  Link to LOCUS view
  Link to H-ANGEL
HIX0032979
  Link to LOCUS view
  Link to H-ANGEL
HIX0032991
  Link to LOCUS view
  Link to H-ANGEL
HIX0032998
  Link to LOCUS view
  Link to H-ANGEL
HIX0056763
  Link to LOCUS view
  Link to H-ANGEL
2cv5_C
2cv5_G
IPR002119
Histone H2A [Family]
IPR007125
Histone core [Domain]
IPR009072
Histone-fold [Domain]
BP:0006334
nucleosome assembly
BP:0007001
chromosome organization and biogenesis (sensu Eukaryota)
CC:0000786
nucleosome
CC:0005634
nucleus
MF:0003677
DNA binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
124 HIP000098642(59) PPI view Transcript viewRep, Catg. I(27), III(4)/31 HIT IDs
UniProt: P12956, RefSeq: NP_001460, GI: 4503841, CCDS: CCDS14021
Shared with Complex 90, Complex 911.
Gene symbol: XRCC6
Definition:
1. ATP-dependent DNA helicase 2 subunit 1 (ATP-dependent DNA helicase II 70 kDa subunit) (Lupus Ku autoantigen protein p70) (Ku70) (70 kDa subunit of Ku antigen) (Thyroid-lupus autoantigen) (TLAA) (CTC box- binding factor 75 kDa subunit) (CTCBF) (CTC75) (DNA-repair protein XRCC6).
2. ATP-dependent DNA helicase, 70 kDa subunit family protein.
HIX0016526
  Link to LOCUS view
  Link to H-ANGEL
1jeq_A
1jey_A
IPR003034
DNA-binding SAP [Domain]
IPR005160
Ku70/Ku80 C-terminal arm [Domain]
IPR005161
Ku70/Ku80, N-terminal alpha/beta [Domain]
IPR006164
Ku [Domain]
IPR006165
ATP-dependent DNA helicase, 70 kDa subunit [Family]
BP:0006303
double-strand break repair via nonhomologous end joining
CC:0005634
nucleus
CC:0005958
DNA-dependent protein kinase complex
MF:0003676
nucleic acid binding
MF:0003677
DNA binding
MF:0004003
ATP-dependent DNA helicase activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
125 HIP000098727(20) PPI view Transcript viewRep, Catg. I(1), III(1)/2 HIT IDs
UniProt: Q15744, RefSeq: NP_001796, GI: 28872800, CCDS: CCDS9589
Shared with Complex 7, Complex 1215.
Gene symbol: CEBPE
Definition:
1. Basic leucine zipper domain containing protein.
2. CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).
HIX0037738
  Link to LOCUS view
  Link to H-ANGEL
IPR004827
Basic-leucine zipper (bZIP) transcription factor [Domain]
IPR011700
Basic leucine zipper [Domain]
BP:0006355
regulation of transcription, DNA-dependent
CC:0005634
nucleus
MF:0003677
DNA binding
MF:0003700
transcription factor activity
MF:0043565
sequence-specific DNA binding
MF:0046983
protein dimerization activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
126 HIP000099143(5) PPI view Transcript viewRep, Catg. I(4), III(1)/5 HIT IDs
UniProt: Q9BZK7, RefSeq: NP_078941, GI: 19913371, CCDS:
Gene symbol: TBL1XR1
Definition:
1. F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1).
2. LisH dimerisation motif, subgroup domain containing protein.
HIX0003871
  Link to LOCUS view
  Link to H-ANGEL
IPR001680
WD40 repeat [Repeat]
IPR006594
LisH dimerisation motif [Domain]
IPR011046
WD40-like [Domain]
IPR013720
LisH dimerisation motif, subgroup [Domain]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
127 HIP000099275(61) PPI view Transcript viewRep, Catg. I(7), II(1), III(2)/10 HIT IDs
UniProt: P11142, Q5RA83, Q71U34, RefSeq: NP_006588, GI: 5729877, CCDS: CCDS8440
Shared with Complex 2.
Gene symbol: HSPA8
Definition:
1. Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).
2. Heat shock protein 70 family protein.
3. Similar to Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8).
HIX0010213
  Link to LOCUS view
  Link to H-ANGEL
IPR001023
Heat shock protein Hsp70 [Family]
IPR013126
Heat shock protein 70 [Family]
MF:0005524
ATP binding
WoLF PSORT
cytosol, nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
128 HIP000100797(2) PPI view Transcript viewRep, Catg. I(1), III(2)/3 HIT IDs
UniProt: P42685, Q9NTR5, RefSeq: NP_002022, GI: 4503787, CCDS: CCDS5103
Gene symbol: FRK
EC No.: EC 2.7.1.112, EC 2.7.10.2
Definition:
1. Src homology-3 domain containing protein.
2. Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK).
HIX0006158
  Link to LOCUS view
  Link to H-ANGEL
IPR000719
Protein kinase, core [Domain]
IPR000980
SH2 motif [Domain]
IPR001245
Tyrosine protein kinase [Domain]
IPR001452
Src homology-3 [Domain]
IPR002290
Serine/threonine protein kinase [Domain]
IPR008266
Tyrosine protein kinase, active site [Active_site]
IPR011009
Protein kinase-like [Domain]
BP:0006468
protein amino acid phosphorylation
BP:0007242
intracellular signaling cascade
MF:0004672
protein kinase activity
MF:0004674
protein serine/threonine kinase activity
MF:0004713
protein-tyrosine kinase activity
MF:0005524
ATP binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
129 HIP000100818(8) PPI view Transcript viewRep, Catg. I(3)/3 HIT IDs
UniProt: Q5RC21, Q5VT41, Q99598, RefSeq: NP_005990, GI: 5174731, CCDS: CCDS1596
Shared with Complex 844.
Gene symbol: TSNAX
Definition:
1. Translin family protein.
2. Translin-associated protein X (Translin-associated factor X).
HIX0001697
  Link to LOCUS view
  Link to H-ANGEL
IPR002848
Translin [Family]
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
130 HIP000100943(8) PPI view Transcript viewRep, Catg. I(1), III(2)/3 HIT IDs
UniProt: P31151, RefSeq: , GI: , CCDS:
Shared with Complex 1234.
Gene symbol: S100A7
Definition:
1. Protein S100-A7 (S100 calcium-binding protein A7) (Psoriasin).
2. S100/CaBP-9k-type, calcium binding, subdomain containing protein.
HIX0023627
  Link to LOCUS view
  Link to H-ANGEL
1psr_A
1psr_B
2psr_A
3psr_A
3psr_B
IPR001751
S100/CaBP-9k-type, calcium binding [Domain]
IPR002048
Calcium-binding EF-hand [Domain]
IPR011992
EF-Hand type [Domain]
IPR013787
S100/CaBP-9k-type, calcium binding, subdomain [Domain]
MF:0005509
calcium ion binding
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
131 HIP000101742(6) PPI view Transcript viewCatg. I(6)/6 HIT IDs
UniProt: Q6Q9Z7, RefSeq: , GI: , CCDS:
Shared with Complex 92.
Gene symbol: E2F6
Definition:
1. Transcription Factor E2F6 family protein.
2. Transcription factor E2F6 (E2F-6). Isoform 2.
HIX0001829
  Link to LOCUS view
  Link to H-ANGEL
IPR003316
Transcription factor E2F/dimerisation partner (TDP) [Domain]
IPR011991
Winged helix repressor DNA-binding [Domain]
IPR015633
E2F Family [Family]
IPR015635
Transcription Factor E2F6 [Family]
BP:0000074
regulation of progression through cell cycle
BP:0006355
regulation of transcription, DNA-dependent
CC:0005667
transcription factor complex
MF:0003700
transcription factor activity
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
132 HIP000102375(8) PPI view Transcript viewRep, Catg. I(3)/3 HIT IDs
UniProt: O96020, RefSeq: NP_477097, GI: 17318565, CCDS: CCDS6264
Shared with Complex 955.
Gene symbol: CCNE2
Definition:
1. Cyclin, A/B/D/E family protein.
2. G1/S-specific cyclin-E2.
HIX0007656
  Link to LOCUS view
  Link to H-ANGEL
IPR004367
Cyclin, C-terminal [Domain]
IPR006670
Cyclin [Domain]
IPR006671
Cyclin, N-terminal [Domain]
IPR011028
Cyclin-like [Domain]
IPR013763
Cyclin-related [Domain]
IPR014400
Cyclin, A/B/D/E [Family]
BP:0000074
regulation of progression through cell cycle
CC:0005634
nucleus
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
133 HIP000102456(28) PPI view Transcript viewRep, Catg. I(47), II(2), III(1)/50 HIT IDs
UniProt: P16213, P61769, P61770, P61771, Q540F8, RefSeq: NP_004039, GI: 4757826, CCDS: CCDS10113
Shared with Complex 131, Complex 216, Complex 331.
Gene symbol: B2M
Definition:
1. Beta 2-microglobulin protein.
2. Beta-2-Microglobulin family protein.
3. Beta-2-microglobulin precursor [Contains: Beta-2-microglobulin variant pI 5.3].
4. Similar to Beta-2-microglobulin precursor [Contains: Beta-2-microglobulin variant pI 5.3].
HIX0012200
  Link to LOCUS view
  Link to H-ANGEL
IPR003597
Immunoglobulin C1-set [Domain]
IPR007110
Immunoglobulin-like [Domain]
IPR013783
Immunoglobulin-like fold [Domain]
IPR015707
Beta-2-Microglobulin [Family]
WoLF PSORT

Target P
signal peptide
SOSUI
membrane protein
TMHMM
soluble protein
134 HIP000102581(1) PPI view Transcript viewRep, Catg. I(5)/5 HIT IDs
UniProt: P04920, RefSeq: , GI: , CCDS: CCDS5917
Definition:
1. AE2 anion exchanger.
2. Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L). Isoform B1.
3. HCO3- transporter, eukaryote family protein.
4. Solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1).
HIX0007222
  Link to LOCUS view
  Link to H-ANGEL
IPR001717
Anion exchange protein [Family]
IPR002978
Anion exchanger, isoform 2 [Family]
IPR003020
HCO3- transporter, eukaryote [Family]
IPR011531
HCO3-transporter, c-terminal [Domain]
IPR013769
HCO3- transporter, cytoplasmic [Domain]
BP:0006820
anion transport
CC:0016020
membrane
CC:0016021
integral to membrane
MF:0005452
inorganic anion exchanger activity
MF:0015380
anion exchanger activity
WoLF PSORT

Target P
Other
SOSUI
membrane protein
TMHMM
membrane protein
135 HIP000102600(10) PPI view Transcript viewRep, Catg. I(3)/3 HIT IDs
UniProt: P55212, RefSeq: NP_001217, GI: 14916483, CCDS: CCDS3684
Shared with Complex 405.
Gene symbol: CASP6
EC No.: EC 3.4.22.59
Definition:
1. Caspase-6 precursor (EC 3.4.22.59) (CASP-6) (Apoptotic protease Mch-2) [Contains: Caspase-6 subunit p18; Caspase-6 subunit p11].
2. Peptidase C14, caspase precursor p45 family protein.
HIX0004436
  Link to LOCUS view
  Link to H-ANGEL
IPR001309
Caspase, p20 subunit [Domain]
IPR002138
Peptidase C14, caspase non-catalytic subunit p10 [Domain]
IPR002398
Peptidase C14, caspase precursor p45 [Family]
IPR011600
Peptidase C14, caspase catalytic [Domain]
IPR015469
Caspase-6 [Family]
BP:0006508
proteolysis
MF:0030693
caspase activity
WoLF PSORT
cytosol, nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
136 HIP000102690(5) PPI view Transcript viewCatg. III(1)/1 HIT IDs
UniProt: Q96BG3, RefSeq: NP_694939, GI: 23397454, CCDS:
Gene symbol: AEBP2
Definition:
1. Zinc finger, C2H2-type domain containing protein.
HIX0010472
  Link to LOCUS view
  Link to H-ANGEL
IPR007087
Zinc finger, C2H2-type [Domain]
CC:0005622
intracellular
MF:0003676
nucleic acid binding
MF:0008270
zinc ion binding
WoLF PSORT
nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
137 HIP000103018(18) PPI view Transcript viewRep, Catg. I(8)/8 HIT IDs
UniProt: P19105, Q53X45, Q5RC34, RefSeq: NP_006462, GI: 5453740, CCDS: CCDS11830
Definition:
1. Calcium-binding EF-hand domain containing protein.
2. Myosin regulatory light chain 2, nonsarcomeric (Myosin RLC).
3. Myosin regulatory light chain.
HIX0014301
  Link to LOCUS view
  Link to H-ANGEL
IPR002048
Calcium-binding EF-hand [Domain]
IPR011992
EF-Hand type [Domain]
MF:0005509
calcium ion binding
WoLF PSORT
mitochondria, cytosol, nuclear, Other
Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
138 HIP000103383(12) PPI view Transcript viewRep, Catg. I(2)/2 HIT IDs
UniProt: P56524, RefSeq: NP_006028, GI: 5174481, CCDS:
Shared with Complex 162.
Gene symbol: HDAC4
Definition:
1. Histone deacetylase 4 (HD4).
2. Histone deacetylase superfamily protein.
HIX0021592
  Link to LOCUS view
  Link to H-ANGEL
IPR000286
Histone deacetylase superfamily [Family]
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
139 HIP000103413(11) PPI view Transcript viewRep, Catg. I(35)/35 HIT IDs
UniProt: Q15014, Q5R905, RefSeq: NP_036418, GI: 6912448, CCDS: CCDS14512
Shared with Complex 11, Complex 719.
Gene symbol: MORF4L2
Definition:
1. MRG family protein.
2. Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).
HIX0016954
  Link to LOCUS view
  Link to H-ANGEL
IPR008676
MRG [Family]
CC:0005634
nucleus
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
140 HIP000103493(84) PPI view Transcript viewCatg. I(1)/1 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Shared with Complex 54, Complex 162, Complex 965, Complex 1267.
Gene symbol: NCOR1
Definition:
1. Myb, DNA-binding domain containing protein.
2. Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).
HIX0013566
  Link to LOCUS view
  Link to H-ANGEL
IPR001005
SANT, DNA-binding [Domain]
IPR009057
Homeodomain-like [Domain]
IPR012287
Homeodomain-related [Domain]
IPR014778
Myb, DNA-binding [Domain]
BP:0045449
regulation of transcription
CC:0005634
nucleus
MF:0003677
DNA binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
141 HIP000103996(160) PPI view Transcript viewRep, Catg. II(1), III(8)/9 HIT IDs
UniProt: O60739, P61220, Q32LJ9, Q4R4X9, Q6FG85, Q9CXU9, RefSeq: NP_005866, GI: 5031711, CCDS: CCDS2690
Shared with Complex 12, Complex 141, Complex 167, Complex 326, Complex 419, Complex 1088.
Gene symbol: EIF1B
Definition:
1. Eukaryotic translation initiation factor SUI1 family protein.
2. Similar to Eukaryotic translation initiation factor 1 (eIF1) (Protein translation factor SUI1 homolog) (Sui1iso1) (A121).
HIX0003193
  Link to LOCUS view
  Link to H-ANGEL
IPR001950
Translation initiation factor SUI1 [Domain]
IPR005874
Eukaryotic translation initiation factor SUI1 [Family]
BP:0006412
translation
BP:0006413
translational initiation
MF:0003743
translation initiation factor activity
WoLF PSORT
cytosol, peroxisome, mitochondria, nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
142 HIP000105386(72) PPI view Transcript viewRep, Catg. I(1), III(5)/6 HIT IDs
UniProt: P05412, RefSeq: NP_002219, GI: 4758616, CCDS: CCDS610
Shared with Complex 7, Complex 87, Complex 257, Complex 403, Complex 1175.
Gene symbol: JUN
Definition:
1. Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39).
2. Transcription factor Jun family protein.
HIX0000635
  Link to LOCUS view
  Link to H-ANGEL
IPR002112
Transcription factor Jun [Family]
IPR004827
Basic-leucine zipper (bZIP) transcription factor [Domain]
IPR005643
Jun-like transcription factor [Domain]
IPR008917
Eukaryotic transcription factor, Skn-1-like, DNA-binding [Domain]
IPR011616
bZIP transcription factor, bZIP_1 [Domain]
IPR015558
c-Jun Transcription Factor [Family]
BP:0006355
regulation of transcription, DNA-dependent
CC:0005634
nucleus
MF:0003700
transcription factor activity
MF:0043565
sequence-specific DNA binding
MF:0046983
protein dimerization activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
143 HIP000105752(51) PPI view Transcript viewRep, Catg. I(6), II(1)/7 HIT IDs
UniProt: Q9H1Y0, RefSeq: NP_004840, GI: 4757798, CCDS: CCDS5055
Shared with Complex 279.
Gene symbol: ATG5
Definition:
1. Autophagy protein 5 (APG5-like) (Apoptosis-specific protein).
2. Autophagy protein Apg5 family protein.
3. Similar to Autophagy protein 5 (APG5-like) (Apoptosis-specific protein).
HIX0006100
  Link to LOCUS view
  Link to H-ANGEL
IPR007239
Autophagy protein Apg5 [Family]
BP:0006914
autophagy
CC:0005737
cytoplasm
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
144 HIP000106108(40) PPI view Transcript viewRep, Catg. I(37), II(3)/40 HIT IDs
UniProt: P63243, P63244, P63245, P63246, P63247, P68040, Q4R7Y4, Q5NCC5, Q5U275, Q6FH47, RefSeq: NP_006089, GI: 5174447, CCDS: CCDS34324
Shared with Complex 44.
Gene symbol: GNB2L1
Definition:
1. Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).
2. Similar to Guanine nucleotide-binding protein subunit beta 2-like 1 (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Receptor of activated protein kinase C 1) (RACK1) (Receptor for activated C kinase).
3. WD40-like domain containing protein.
HIX0005509
  Link to LOCUS view
  Link to H-ANGEL
IPR001680
WD40 repeat [Repeat]
IPR011046
WD40-like [Domain]
WoLF PSORT
nuclear, cytosol, extracellular, Other
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
145 HIP000106475(5) PPI view Transcript viewCatg. I(1)/1 HIT IDs
UniProt: Q92994, RefSeq: NP_001510, GI: 22035556, CCDS: CCDS10001
Gene symbol: BRF1
Definition:
1. Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B- related factor 1) (BRF-1) (hBRF) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2) (TAF3B2). Isoform 5.
2. Transcription factor TFIIB related family protein.
HIX0012028
  Link to LOCUS view
  Link to H-ANGEL
IPR000812
Transcription factor TFIIB related [Family]
IPR006670
Cyclin [Domain]
IPR011028
Cyclin-like [Domain]
IPR011665
Brf1-like TBP-binding [Domain]
IPR013137
Zinc finger, TFIIB-type [Domain]
IPR013150
Transcription factor TFIIB, cyclin-related [Domain]
IPR013763
Cyclin-related [Domain]
BP:0006352
transcription initiation
BP:0006355
regulation of transcription, DNA-dependent
BP:0045449
regulation of transcription
BP:0045941
positive regulation of transcription
CC:0005634
nucleus
CC:0005667
transcription factor complex
MF:0008270
zinc ion binding
MF:0016563
transcriptional activator activity
MF:0030528
transcription regulator activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
146 HIP000108582(18) PPI view Transcript viewRep, Catg. I(1), III(3)/4 HIT IDs
UniProt: O15151, RefSeq: NP_002384, GI: 88702791, CCDS: CCDS1447
Shared with Complex 424.
Gene symbol: MDM4
Definition:
1. MDM4/MDMX protein family protein.
2. Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).
HIX0019963
  Link to LOCUS view
  Link to H-ANGEL
IPR001841
Zinc finger, RING-type [Domain]
IPR001876
Zinc finger, RanBP2-type [Domain]
IPR003121
SWIB/MDM2 [Domain]
IPR015458
MDM4/MDMX protein [Family]
CC:0005622
intracellular
CC:0005634
nucleus
MF:0005515
protein binding
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
147 HIP000109795(1) PPI view Transcript viewCatg. I(1)/1 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Gene symbol: PELP1
Definition:
1. NUC201 domain containing protein.
2. Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3). Isoform 2.
HIX0039094
  Link to LOCUS view
  Link to H-ANGEL
IPR012583
NUC201 [Domain]
IPR012980
Protein of unknown function NUC202 [Domain]
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
148 HIP000111746(19) PPI view Transcript viewRep, Catg. I(4), IV(3)/7 HIT IDs
UniProt: Q14686, RefSeq: NP_054790, GI: 32307128, CCDS: CCDS13241
Shared with Complex 49.
Gene symbol: NCOA6
Definition:
1. Conserved hypothetical protein.
2. Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).
HIX0015752
  Link to LOCUS view
  Link to H-ANGEL
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
149 HIP000112395(13) PPI view Transcript viewRep, Catg. I(19)/19 HIT IDs
UniProt: P62937, P62938, P62940, P62941, Q0ZQK6, Q0ZQK7, Q0ZQK8, Q0ZQL0, Q0ZQL1, Q0ZQL2, Q5R8S7, RefSeq: XP_945701, GI: 113429184, CCDS: CCDS5494
Shared with Complex 156.
Gene symbol: PPIA
EC No.: EC 5.2.1.8
Definition:
1. Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein).
2. Peptidyl-prolyl cis-trans isomerase, cyclophilin-type domain containing protein.
HIX0006653
  Link to LOCUS view
  Link to H-ANGEL
1ak4_A
1ak4_B
1awq_A
1awr_A
1awr_B
1awr_C
1awr_D
1awr_E
1awr_F
1aws_A
1awt_A
1awt_B
1awt_C
1awt_D
1awt_E
1awt_F
1awu_A
1awv_A
1awv_B
1awv_C
1awv_D
1awv_E
1awv_F
1bck_A
1cwa_A
1cwb_A
1cwc_A
1cwf_A
1cwh_A
1cwi_A
1cwj_A
1cwk_A
1cwl_A
1cwm_A
1cwo_A
1fgl_A
1m63_C
1m63_G
1m9c_A
1m9c_B
1m9d_A
1m9d_B
1m9e_A
1m9e_B
1m9f_A
1m9f_B
1m9x_A
1m9x_B
1m9x_E
1m9x_F
1m9y_A
1m9y_B
1m9y_E
1m9y_F
1mf8_C
1mik_A
1nmk_A
1nmk_B
1oca_A
1rmh_A
1rmh_B
1vbs_A
1vbt_A
1vbt_B
1w8l_A
1w8m_A
1w8v_A
1ynd_A
1ynd_B
1zkf_A
1zkf_B
2alf_A
2cpl_A
2cyh_A
2rma_A
2rma_C
2rma_E
2rma_G
2rma_I
2rma_K
2rma_M
2rma_O
2rma_Q
2rma_S
2rmb_A
2rmb_C
2rmb_E
2rmb_G
2rmb_I
2rmb_K
2rmb_M
2rmb_O
2rmb_Q
2rmb_S
3cyh_A
4cyh_A
5cyh_A
IPR002130
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type [Domain]
BP:0006457
protein folding
WoLF PSORT
cytosol, peroxisome
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
150 HIP000113162(51) PPI view Transcript viewRep, Catg. I(2), III(1)/3 HIT IDs
UniProt: , RefSeq: NP_002383, GI: 89993689, CCDS:
Shared with Complex 4, Complex 768, Complex 1001, Complex 1201.
Gene symbol: MDM2
EC No.: EC 6.3.2.-
Definition:
1. SWIB/MDM2 domain containing protein.
2. Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2).
HIX0036698
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IPR001841
Zinc finger, RING-type [Domain]
IPR001876
Zinc finger, RanBP2-type [Domain]
IPR003121
SWIB/MDM2 [Domain]
CC:0005622
intracellular
CC:0005634
nucleus
MF:0005515
protein binding
MF:0008270
zinc ion binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
151 HIP000115835(4) PPI view Transcript viewRep, Catg. I(4), II(1), III(1)/6 HIT IDs
UniProt: Q9NVH6, RefSeq: NP_060666, GI: 8922625, CCDS: CCDS14768
Gene symbol: TMLHE
EC No.: EC 1.14.11.8
Definition:
1. Similar to Trimethyllysine dioxygenase, mitochondrial precursor (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (TML-alpha- ketoglutarate dioxygenase) (TML hydroxylase) (TML dioxygenase) (TMLD).
2. Taurine catabolism dioxygenase TauD/TfdA family protein.
3. Trimethyllysine dioxygenase, mitochondrial precursor (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (TML-alpha- ketoglutarate dioxygenase) (TML hydroxylase) (TML dioxygenase) (TMLD).
HIX0017170
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IPR003819
Taurine catabolism dioxygenase TauD/TfdA [Family]
IPR012776
Trimethyllysine dioxygenase [Family]
BP:0006118
electron transport
BP:0045329
carnitine biosynthetic process
MF:0005506
iron ion binding
MF:0016491
oxidoreductase activity
MF:0031418
L-ascorbic acid binding
MF:0050353
trimethyllysine dioxygenase activity
WoLF PSORT
mitochondria, cytosol, peroxisome, Other
Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein
152 HIP000116683(1) PPI view Transcript viewCatg. II(2)/2 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Gene symbol: PIK3R1
Definition:
1. PI3 kinase, P85 regulatory subunit family protein.
2. Similar to Phosphoinositide-3-kinase regulatory subunit (Fragment).
HIX0004914
  Link to LOCUS view
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IPR000980
SH2 motif [Domain]
IPR001720
PI3 kinase, P85 regulatory subunit [Family]
BP:0007242
intracellular signaling cascade
CC:0005942
phosphoinositide 3-kinase complex
MF:0035014
phosphoinositide 3-kinase regulator activity
WoLF PSORT
cytosol, nuclear
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
153 HIP000116687(8) PPI view Transcript viewRep, Catg. I(4)/4 HIT IDs
UniProt: Q92569, RefSeq: , GI: , CCDS:
Shared with Complex 6.
Gene symbol: PIK3R3
Definition:
1. PI3 kinase, P85 regulatory subunit family protein.
2. Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).
3. Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK). Isoform 2.
HIX0000542
  Link to LOCUS view
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IPR000980
SH2 motif [Domain]
IPR001720
PI3 kinase, P85 regulatory subunit [Family]
BP:0007242
intracellular signaling cascade
CC:0005942
phosphoinositide 3-kinase complex
MF:0035014
phosphoinositide 3-kinase regulator activity
WoLF PSORT

Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
154 HIP000161424(1) PPI view Transcript viewCatg. III(1)/1 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Gene symbol: BNC2
Definition:
1. Zinc finger, C2H2-type domain containing protein.
HIX0007935
  Link to LOCUS view
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IPR007087
Zinc finger, C2H2-type [Domain]
CC:0005622
intracellular
MF:0003676
nucleic acid binding
MF:0008270
zinc ion binding
WoLF PSORT
nuclear, cytosol
Target P
Other
SOSUI
soluble protein
TMHMM
soluble protein
155 HIP000171840(9) PPI view Transcript viewRep, Catg. I(9)/9 HIT IDs
UniProt: , RefSeq: , GI: , CCDS:
Shared with Complex 356.
Gene symbol: BAG1
Definition:
1. BAG family molecular chaperone regulator 1 (BCL-2-binding athanogene- 1) (BAG-1) (Glucocorticoid receptor-associated protein RAP46).
2. Ubiquitin domain containing protein.
HIX0007978
  Link to LOCUS view
  Link to H-ANGEL
IPR000626
Ubiquitin [Domain]
IPR003103
Apoptosis regulator Bcl-2 protein, BAG [Domain]
BP:0006464
protein modification process
BP:0006915
apoptosis
MF:0005515
protein binding
WoLF PSORT

Target P
Not predicted
SOSUI
soluble protein
TMHMM
soluble protein