H-InvDB x AHG DB
Protein view
H-InvDB_9.0 released on May 27, 2015.
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H-Inv protein ID: HIP000051007 Last modified: 27-May-2015
Definition: Similar to Heterogeneous nuclear ribonucleoprotein K isoform a.
[Summery][Full]
[Protein Info][Member][Motif] provide location, ID and descriptions of functional motifs (InterPro)[Function] provide human-curated functional definition, similarity category and related evidences; Gene name; HUGO gene symbols; GO term; EC number; pathway information (KEGG)[PTM][Subcellular loc.] provide subcellular localization prediction by WolfPSORT, Target P, SOSUI, TMHMM and PTS1[Protein Structure][Evolutionary info.] provide orthologs relationships, phylogenic trees and sequence alignments[Polymorphism/repeat] provide polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information

Protein information
HIP ID HIP000051007
Length 464
Codon Adaptation Index (CAI). 0.738
Database links RefSeq NA
UniProt NA
CCDS NA
Original transcript information
Representative H-Inv transcript ID Transcript view HIT000323341
H-Inv cluster ID Locus view HIX0008131
Predicted CDS 210..1604 ; 464[aa] ; Orientation:+3 ;
Genomic location Chromosome 9
Location 9q21.32
CDS position 86583092-86595519
Strand -
Accession number X72727.1
CAGE tag ID NA
EST ID NA
Clone Number tunps A,B,C,D
Experimental resources NBRC: NITE Biological Resource Center NBRC      
Length of cDNA 2830[bp] (No. of exon:16)[A:805 T:841 G:654 C:530] ;
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:3190 ;
KEGG GENES KEGG GENES(3190) ;
GeneCard GeneCard NA
etc H-GOLD Human-Gene diversity Of Life-style related Diseases ;
Protein view

Coresponding transcript member (s)
No.1
H-Inv IDTranscript view HIT000323341
H-Inv cluster IDLocus view HIX0008131
Accession numberX72727.1
CAGE tag IDNA
EST IDNA
Coding potential Help Protein coding
DefinitionSimilar to Heterogeneous nuclear ribonucleoprotein K isoform a.
Similarity category HelpSimilar to known protein(Category II).
Similar to known protein (NP_002131) [Identity/coverage = 99.784%/100.0%] to Homo sapiens protein.
Transcript feature Help NA
Genomic Location G-integra Help Chromosome9
Location9q21.32
CDS position86583092-86595519
Strand-
Gene structure16 exons

Motif information in predicted CDS
ORF

length(465),orf(210:1604) METEQPEETFPNTETNGEFGKRPAEDMEEEQDFKRSRNTDEMVELRILLQ SKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEI LKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLL IHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPD RVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRP VGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRG GSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAID TWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAG SIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYL LQNSVKQYADVEGF*		 a.a.
length		 InterPro Name
length(43), motif(1:43) 43IPR012987ROK, N-terminal [Domain]
length(73), motif(38:110) 73IPR004088K Homology domain, type 1 [Domain]
length(69), motif(41:109) 69IPR004087K Homology domain [Domain]
length(63), motif(42:104) 63IPR004088K Homology domain, type 1 [Domain]
length(59), motif(45:103) 59IPR004088K Homology domain, type 1 [Domain]
length(80), motif(141:220) 80IPR004088K Homology domain, type 1 [Domain]
length(80), motif(142:221) 80IPR004088K Homology domain, type 1 [Domain]
length(72), motif(143:214) 72IPR004087K Homology domain [Domain]
length(66), motif(144:209) 66IPR004088K Homology domain, type 1 [Domain]
length(63), motif(147:209) 63IPR004088K Homology domain, type 1 [Domain]
length(79), motif(379:457) 79IPR004088K Homology domain, type 1 [Domain]
length(74), motif(385:458) 74IPR004088K Homology domain, type 1 [Domain]
length(71), motif(386:456) 71IPR004087K Homology domain [Domain]
length(65), motif(387:451) 65IPR004088K Homology domain, type 1 [Domain]
length(62), motif(389:450) 62IPR004088K Homology domain, type 1 [Domain]

Protein function information
H-Inv protein ID HIP000051007
Representative H-Inv transcript ID Transcript view HIT000323341
H-Inv cluster ID Locus view HIX0008131
Definition Similar to Heterogeneous nuclear ribonucleoprotein K isoform a.
Similarity category Help Similar to known protein(Category II).
Similar to known protein (NP_002131) [Identity/coverage = 99.784%/100.0%] to Homo sapiens protein.
Gene family/group H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
EC number NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer No. of interaction 18
Interaction partner(s) HIP000022035; HIP000022049; HIP000022971; HIP000022971; HIP000023960; HIP000025001; HIP000030471; HIP000039590; HIP000039653; HIP000040680; HIP000057536; HIP000058310; HIP000064456; HIP000076215; HIP000076215; HIP000079240; HIP000091500; HIP000095024;
BIND 145824; 177285; 177286; 19219; 24463; 24472; 263126; 50116; 50117; 50266; 54906; 57935; 57936; 57937; 57938;
DIP 102592E; 111677E; 111706E; 112072E; 144758E; 151748E; 151750E; 151752E; 175753E; 179997E; 185077E; 185374E;
MINT MINT-2855592; MINT-2859739; MINT-2859758; MINT-2859777; MINT-3296872; MINT-5205854; MINT-6803834; MINT-6803853; MINT-6803869; MINT-6803896; MINT-6803939; MINT-6823857; MINT-6823877; MINT-7035260; MINT-7035286; MINT-7035298; MINT-7035309; MINT-7035323; MINT-7035338; MINT-7945693; MINT-7947479; MINT-8200625; MINT-8200636; MINT-8200651; MINT-8201404; MINT-8201427; MINT-8201449;
HPRD 00146; 00298; 00496; 00535; 00579; 00589; 00655; 00796; 01095; 01228; 01284; 01301; 01501; 01726; 01746; 01801; 01818; 01819; 02186; 02511; 02877; 03128; 03129; 03144; 03158; 03183; 03926; 04066; 04184; 04205; 04207; 04257; 04340; 04360; 04530; 05059; 05088; 05156; 05270; 05378; 05496; 06515; 06691; 07601; 09045; 09060; 09113; 09273; 10007; 11303; 11488; 11535; 12048; 12752; 13775; 14358; 15334; 15998; 16246; 17835; 18043;
IntAct NA
Database links RefSeq NA
UniProt NA
CCDS NA
Gene symbol/name HGNC symbol NA
HGNC aliases NA
HGNC name NA
Related H-InvDB links G-integraG-integra ; PPI viewer PPI view ; TACT TACT ;

Glycosylation
GPDB (GlycoProtDB)
GPDB 		ID NA
Protein name NA
Organism NA
Length(aa) NA

Subcellular localization information
WoLF PSORT nuclear;
Target P Other
SOSUI soluble protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified : 27-May-2015
Start End PDB_ID E-value Identity Coverage SCOP_ID
40 110 2axyA1 3e-10 29.6 71/71 d.51.1.1
144 251 2dp9A1 2e-17 11.0 100/120 b.122.1.5
384 457 1we8A 2e-04 17.1 74/104 d.51.1.1
Related H-InvDB links GTOP GTOP

Translation polymorphism (SNP) and microsatellite (STR) information

Single Nucleotide Polymorphism (SNP) and indel VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
215..215 A/G rs202064506 - CDS Synonymous[Glu2Glu]
225..225 C/T rs150076109 - CDS Nonsynonymous[Pro6Ser]
254..254 C/T rs199952772 - CDS Synonymous[Thr15Thr]
281..281 A/C rs114536498 - CDS Synonymous[Ala24Ala]
284..284 A/G rs11548845 + CDS Synonymous[Glu25Glu]
452..452 C/T rs201251896 - CDS Synonymous[Ser81Ser]
530..530 C/T rs11548846 + CDS Synonymous[Thr107Thr]
595..595 C/G rs140707980 - CDS Nonsynonymous[Ala129Gly]
644..644 C/T rs116557087 - CDS Synonymous[Cys145Cys]
728..728 C/T rs143811423 - CDS Synonymous[Asn173Asn]
737..737 C/G rs201881795 - CDS Synonymous[Thr176Thr]
802..802 A/G rs111725016 - CDS Nonsynonymous[Lys198Arg]
899..899 C/T rs200783060 - CDS Synonymous[Tyr230Tyr]
1193..1193 A/G rs140679593 - CDS Synonymous[Arg328Arg]
1271..1271 A/T rs114279043 - CDS Synonymous[Pro354Pro]
1311..1311 G/C rs182293768 - CDS Nonsynonymous[Gly368Arg]
1328..1328 T/C rs143712714 - CDS Synonymous[Tyr373Tyr]
1349..1349 T/C rs181141777 - CDS Synonymous[Tyr380Tyr]
1415..1415 T/C rs115527397 - CDS Synonymous[Ile402Ile]
1445..1445 A/G rs61755088 - CDS Synonymous[Gln412Gln]
1499..1499 C/T rs115346013 - CDS Synonymous[Ser430Ser]
Microsatellite (Short Tandem Repeat, STR)
LocationVariationStrand
No data available
Related H-InvDB links
VaryGeneVaryGene ;