H-InvDB_9.0 released on May 27, 2015. Search by Keyword H-Inv ID (HIT) H-Inv cluster ID (HIX) H-Inv protein ID (HIP) H-Inv gene family/group (HIF) Accession number Chromosome number Chromosome band Definition* Data source ID --- CCDS ID dbSNP ID (rs number) EC number Ensembl ID EntrezGene ID FR ID FR Accession number GO ID GO name* HGNC gene symbol HGNC gene name* InterPro ID InterPro name* OMIM ID OMIM title* Pathway ID Pathway name* RefSeq (gene) ID RefSeq (protein) ID SCOP ID UniProt for Advanced Search

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H-Inv protein ID:	HIP000082794	Last modified:	27-May-2015
Definition:	Similar to Tumor necrosis factor ligand superfamily member 13 isoform gamma proprotein.

Select FormatXML fileFlat fileProtein sequence fasta

Protein information HIP ID HIP000082794 Length 247 Codon Adaptation Index (CAI). 0.758 Database links RefSeq NA UniProt NA CCDS Original transcript information Representative H-Inv transcript ID HIT000069829 H-Inv cluster ID HIX0013500 Predicted CDS 254..997 ; 247[aa] ; Orientation:+2 ; Genomic location Chromosome 17 Location 17p13.1 CDS position 7462104-7464918 Strand + Accession number AF114013.1 CAGE tag ID NA EST ID NA Clone Number NA Experimental resources NBRC     Antibody (TNFSF13) ;   Catalog (TNFSF13) ; Length of cDNA 1607[bp] (No. of exon:7)[A:340 T:363 G:426 C:478] ; Database links RefSeq NA Ensembl NA Entrez Gene Entrez Gene ID:8741 ; KEGG GENES KEGG GENES(8741) ; GeneCard TNFSF13 ; etc Human-Gene diversity Of Life-style related Diseases ;

MPASSPFLLAPKGPPGNMGGPVREPALSVALWLSWGAALGAVACAMALLTQQTELQSLRREVSRLQGTGGPSQNGEGYPWQSLPEQSSDALEAWENGERSRKRRAVLTQKQKKQHSVLHLVPINATSKDDSDVTEVMWQPALRRGRGLQAQGYGVRIQDAGVYLLYSQVLFQDVTFTMGQVVSREGQGRQETLFRCIRSMPSHPDRAYNSCYSAGVFHLHQGDILSVIIPRARAKLNLSPHGTFLGL*

Coresponding transcript member (s)

No.		1
H-Inv ID		HIT000069829
H-Inv cluster ID		HIX0013500
Accession number		AF114013.1
CAGE tag ID		NA
EST ID		NA
Coding potential		Protein coding
Definition		Similar to Tumor necrosis factor ligand superfamily member 13 isoform gamma proprotein.
Similarity category		Similar to known protein(Category II).
		Similar to known protein (NP_742085) [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Transcript feature		Representative transcript; Splicing isoform;
Genomic Location	Chromosome	17
	Location	17p13.1
	CDS position	7462104-7464918
	Strand	+
Gene structure		7 exons

Motif information in predicted CDS

	a.a. length	InterPro	Name
	134	IPR008983	Tumour necrosis factor-like domain [Domain]
	133	IPR008983	Tumour necrosis factor-like domain [Domain]
	132	IPR006052	Tumour necrosis factor domain [Domain]
	131	IPR006052	Tumour necrosis factor domain [Domain]
	101	IPR006052	Tumour necrosis factor domain [Domain]
	17	IPR021184	Tumour necrosis factor, conserved site [Conserved_site]

Protein function information

H-Inv protein ID		HIP000082794
Representative H-Inv transcript ID		HIT000069829
H-Inv cluster ID		HIX0013500
Definition		Similar to Tumor necrosis factor ligand superfamily member 13 isoform gamma proprotein.
Similarity category		Similar to known protein(Category II).
		Similar to known protein (NP_742085) [Identity/coverage = 100.0%/100.0%] to Homo sapiens protein.
Gene family/group	H-Inv gene family/group ID	NA
	Gene family/group name	NA
	Evidence motif (InterPro) ID	NA
EC number		NA
KEGG metabolic pathway		NA
Protein-protein interaction (PPI)	No. of interaction	14
	Interaction partner(s)	HIP000022035; HIP000022049; HIP000030471; HIP000032450; HIP000036913; HIP000036913; HIP000039653; HIP000040680; HIP000041686; HIP000057536; HIP000064456; HIP000075877; HIP000079240; HIP000083074;
	BIND	NA
	DIP	11062E; 11067E;
	MINT	NA
	HPRD	04122; 05365;
	IntAct	NA
Database links	RefSeq	NA
	UniProt
	CCDS
Gene symbol/name	HGNC symbol	TNFSF13
	HGNC aliases	NA
	HGNC name	tumor necrosis factor (ligand) superfamily, member 13;
Related H-InvDB links		G-integra ; PPI view ; TACT ;

Glycosylation GPDB (GlycoProtDB) ID NA Protein name NA Organism NA Length(aa) NA

Subcellular localization information WoLF PSORT peroxisome; Target P signal peptide SOSUI soluble protein TMHMM membrane protein PTS1 Not targeted Related H-InvDB links LIFEdb;  JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP)

Last modified : 27-May-2015

Start End PDB_ID E-value Identity Coverage SCOP_ID 116 247 1jh5A 4e-25 35.4 130/144 b.22.1.1

Related H-InvDB links GTOP

Evolutionary information

Relationship	Species	Accession number	MGI	Links
Orthology	Rattus sp. (Rat)	BC087135		G-integra
Orthology	Bos sp. (Cow)	BC103223		G-integra
Orthology	Macaca sp. (Macaque)	ENSMMUT00000008874		G-integra
Orthology	Monodelphis sp. (Opossum)	ENSMODT00000040113		G-integra
Orthology	Mus sp. (Mouse)	ENSMUST00000108648		G-integra
Orthology	Pongo sp. (Orangutan)	ENSPPYT00000009277		G-integra
Orthology	Canis sp. (Dog)	EU909456		G-integra
Orthology	Pan sp. (Chimpanzee)	XM_001171420		G-integra
Orthology	Equus sp. (Horse)	XM_001918372		G-integra

Phylogenetic tree [View by ATV]	TNeighbor-joining (phb)
Related H-InvDB links	Evola;  dN/dS;

Translation polymorphism (SNP) and microsatellite (STR) information

Single Nucleotide Polymorphism (SNP) and indel Location Variation dbSNP ID Strand CDS/UTR Translation 317..317 G/C rs138476542 + CDS Nonsynonymous[Val22Leu] 365..365 G/T rs201860460 + CDS Nonsynonymous[Ala38Ser] 366..366 C/T rs142987696 + CDS Nonsynonymous[Ala38Val] 452..452 G/A rs11552708 + CDS Nonsynonymous[Gly67Arg] 474..474 A/G rs138823376 + CDS Nonsynonymous[Asn74Ser] 478..478 G/C rs12942687 + CDS Synonymous[Gly75Gly] 540..540 A/G rs3803800 + CDS Nonsynonymous[Asn96Ser] 625..625 C/T rs138604224 + CDS Synonymous[Asn124Asn] 664..664 G/A rs148497612 + CDS Nonsynonymous[Met137Ile] 681..681 G/- rs34476700 + CDS 732..732 C/T rs7503669 + CDS Nonsynonymous[Ala160Val] 833..833 T/C rs145345809 + CDS Nonsynonymous[Phe194Leu] 842..842 A/G rs147443869 + CDS Nonsynonymous[Ile197Val] 856..856 C/T rs61760045 + CDS Synonymous[Pro201Pro] 864..864 C/T rs139748549 + CDS Nonsynonymous[Pro204Leu] 867..867 A/T rs141602266 + CDS Nonsynonymous[Asp205Val] 869..869 C/T rs201011600 + CDS Nonsynonymous[Arg206Trp] 875..875 T/G rs145250389 + CDS Nonsynonymous[Tyr208Asp] 941^942 -/C rs34362644 + CDS 955..955 G/A rs150976338 + CDS Synonymous[Ala234Ala] Microsatellite (Short Tandem Repeat, STR) Location Variation Strand No data available Related H-InvDB links VaryGene ;