H-InvDB x AHG DB
Protein view
H-InvDB_9.0 released on May 27, 2015.
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H-Inv protein ID: HIP000097055 Last modified: 27-May-2015
Definition: Similar to Beta-adducin isoform f.
[Summery][Full]
[Protein Info][Member][Motif] 
provide location, ID and descriptions of functional motifs (InterPro)[Function] 
provide human-curated functional definition, similarity
category and related evidences;  Gene name; 
HUGO gene symbols; GO term; EC number; pathway information (KEGG)[PTM][Subcellular loc.] 
provide subcellular localization prediction by WolfPSORT, Target P, SOSUI, TMHMM and PTS1[Protein Structure][Evolutionary info.] 
provide orthologs relationships, phylogenic trees and sequence alignments[Polymorphism/repeat] 
provide polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information

Protein information
HIP ID HIP000097055
Length 279
Codon Adaptation Index (CAI). 0.799
Database links RefSeq NA
UniProt NA
CCDS NA
Original transcript information
Representative H-Inv transcript ID Transcript view HIT000243594
H-Inv cluster ID Locus view HIX0029808
Predicted CDS 38..876 ; 279[aa] ; Orientation:+2 ;
Genomic location Chromosome 2
Location 2p13.3
CDS position 70901801-70933575
Strand -
Accession number AF486421.1
CAGE tag ID NA
EST ID NA
Clone Number NA
Experimental resources NBRC: NITE Biological Resource Center NBRC     Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (ADD2) ;   Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (ADD2) ;
Length of cDNA 876[bp] (No. of exon:7)[A:233 T:140 G:252 C:251] ;
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:119 ;
KEGG GENES KEGG GENES(119) ;
GeneCard GeneCard ADD2 ;
etc H-GOLD Human-Gene diversity Of Life-style related Diseases ;
Protein view


Coresponding transcript member (s)
No.1
H-Inv IDTranscript view HIT000243594
H-Inv cluster IDLocus view HIX0029808
Accession numberAF486421.1
CAGE tag IDNA
EST IDNA
Coding potential Help Protein coding
DefinitionSimilar to Beta-adducin isoform f.
Similarity category HelpSimilar to known protein(Category II).
Similar to known protein (NP_001171984) [Identity/coverage = 100.0%/34.61%] to Homo sapiens protein.
Transcript feature Help Splicing isoformSplicing isoform;
Genomic Location G-integra Help Chromosome2
Location2p13.3
CDS position70901801-70933575
Strand-
Gene structure7 exons

Motif information in predicted CDS
ORF

length(279),orf(38:876)
MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQ
KKRVTMILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHA
VFPTSSMNVSMMTPINDLHTADSLNLAKGERLMRCKISSVYRLLDLYGWA
QLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKEVLEMRNKIREQN
RQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNP
FSQLTDQELEEYKKEVERKKLELDETGQE
a.a.
length
InterPro Name
length(187), motif(1:187) 187IPR027773Beta-adducin [Family]
length(58), motif(130:187) 58IPR001303Class II aldolase/adducin N-terminal [Domain]
length(62), motif(130:191) 62IPR001303Class II aldolase/adducin N-terminal [Domain]
length(63), motif(136:198) 63IPR001303Class II aldolase/adducin N-terminal [Domain]

Protein function information
H-Inv protein ID HIP000097055
Representative H-Inv transcript ID Transcript view HIT000243594
H-Inv cluster ID Locus view HIX0029808
Definition Similar to Beta-adducin isoform f.
Similarity category Help Similar to known protein(Category II).
Similar to known protein (NP_001171984) [Identity/coverage = 100.0%/34.61%] to Homo sapiens protein.
Gene family/group H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
EC number NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
UniProt NA
CCDS NA
Gene symbol/name HGNC symbol ADD2
HGNC aliases NA
HGNC name adducin 2 (beta);
Related H-InvDB links G-integraG-integra ; PPI viewer PPI view ; TACT TACT ;

Glycosylation
GPDB (GlycoProtDB)
GPDB
ID NA
Protein name NA
Organism NA
Length(aa) NA

Subcellular localization information
WoLF PSORT cytosol;
Target P Other
SOSUI soluble protein
TMHMM soluble protein
PTS1 NA
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Translation polymorphism (SNP) and microsatellite (STR) information

Single Nucleotide Polymorphism (SNP) and indel VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
44..44 G/A rs200519011 - CDS Nonsynonymous[Glu3Lys]
84..84 A/G rs201443444 - CDS Nonsynonymous[Gln16Arg]
87..87 G/A rs34241538 + CDS Nonsynonymous[Gly17Glu]
119..119 G/A rs4986 + CDS Nonsynonymous[Asp28Asn]
154..154 G/A rs141187526 - CDS Synonymous[Ala39Ala]
162..162 G/A rs144732476 - CDS Nonsynonymous[Arg42Gln]
169..169 C/G rs138167651 - CDS Nonsynonymous[Asp44Glu]
236..236 C/T rs114456016 - CDS Synonymous[Leu67Leu]
243..243 G/T rs149147182 - CDS Nonsynonymous[Gly69Val]
289..289 C/A rs17006140 - CDS Synonymous[Ile84Ile]
298..298 G/A rs144778680 - CDS Synonymous[Leu87Leu]
307..307 C/T rs200212314 - CDS Synonymous[Ile90Ile]
308..308 G/A rs150703767 - CDS Nonsynonymous[Ala91Thr]
330..330 C/G rs4987 + CDS Nonsynonymous[Ser98Cys]
346..346 G/A rs144423262 - CDS Synonymous[Pro103Pro]
425..425 G/A rs75081591 - CDS Nonsynonymous[Glu130Lys]
434..434 A/C rs145968821 - CDS Nonsynonymous[Met133Leu]
475..475 C/G rs114904807 - CDS Synonymous[Leu146Leu]
537..537 A/G rs138007719 - CDS Nonsynonymous[His167Arg]
583..583 G/A rs150383515 - CDS Synonymous[Ala182Ala]
590..590 C/T rs200581515 - CDS Synonymous[Leu185Leu]
621..621 A/G rs112879637 - CDS Nonsynonymous[Lys195Arg]
628..628 A/C rs145174076 - CDS Synonymous[Arg197Arg]
658..658 G/C rs115841739 - CDS Synonymous[Ala207Ala]
685..685 C/T rs148402316 - CDS Synonymous[Ser216Ser]
694..694 C/G rs201133279 - CDS Synonymous[Ala219Ala]
702..702 G/C rs149689098 - CDS Nonsynonymous[Ser222Thr]
705..705 G/T rs114311724 - CDS Nonsynonymous[Arg223Leu]
746..746 G/A rs139586218 - CDS Nonsynonymous[Glu237Lys]
774..774 C/T rs114897963 - CDS Nonsynonymous[Thr246Met]
796..796 A/G rs115445925 - CDS Synonymous[Gln253Gln]
Microsatellite (Short Tandem Repeat, STR)
LocationVariationStrand
No data available
Related H-InvDB links
VaryGeneVaryGene ;