H-InvDB x AHG DB
Protein view
H-InvDB_9.0 released on May 27, 2015.
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H-Inv protein ID: HIP000105531 Last modified: 27-May-2015
Definition: Homeobox protein Hox-A13; Homeobox protein Hox-1J;
[Summery][Full]
[Protein Info][Member][Motif] 
provide location, ID and descriptions of functional motifs (InterPro)[Function] 
provide human-curated functional definition, similarity
category and related evidences;  Gene name; 
HUGO gene symbols; GO term; EC number; pathway information (KEGG)[PTM][Subcellular loc.] 
provide subcellular localization prediction by WolfPSORT, Target P, SOSUI, TMHMM and PTS1[Protein Structure][Evolutionary info.] 
provide orthologs relationships, phylogenic trees and sequence alignments[Polymorphism/repeat] 
provide polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information

Protein information
HIP ID HIP000105531
Length 388
Codon Adaptation Index (CAI). 0.728
Database links RefSeq NA
UniProt NA
CCDS NA
Original transcript information
Representative H-Inv transcript ID Transcript view HIT000265606
H-Inv cluster ID Locus view HIX0201189
Predicted CDS 30..1196 ; 388[aa] ; Orientation:+3 ;
Genomic location Chromosome 7
Location 7p15.2
CDS position 27236577-27239725
Strand -
Accession number BC075791.1
CAGE tag ID NA
EST ID NA
Clone Number MGC:86983 IMAGE:30341785
Experimental resources NBRC: NITE Biological Resource Center NBRC      
Length of cDNA 2453[bp] (No. of exon:2)[A:613 T:587 G:605 C:648] ;
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:3209 ;
KEGG GENES KEGG GENES(3209) ;
GeneCard GeneCard NA
etc H-GOLD Human-Gene diversity Of Life-style related Diseases ;
Protein view


Coresponding transcript member (s)
No.1
H-Inv IDTranscript view HIT000265606
H-Inv cluster IDLocus view HIX0201189
Accession numberBC075791.1
CAGE tag IDNA
EST IDNA
Coding potential Help Protein coding
DefinitionHomeobox protein Hox-A13; Homeobox protein Hox-1J;
Similarity category HelpIdentical to known human protein(Category I).
Identical to known human protein (P31271) [Identity/coverage = 99.742%/100.0%] to Homo sapiens (Human). protein.
Transcript feature Help Representative H-Inv IDRepresentative transcript;
Genomic Location G-integra Help Chromosome7
Location7p15.2
CDS position27236577-27239725
Strand-
Gene structure2 exons

Motif information in predicted CDS
ORF

length(389),orf(30:1196)
MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAAAAAAAA
AGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPV
AASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAA
KQCSPCSAAAQSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASA
AAAAAFADKYMDTAGPAAEEFSSRAKEFAFYHQGYAAGPYHHHQPMPGYL
DMPVVPGLGGPGESRHEPLGLPMESYQPWALPNGWNGQMYCPKEQAQPPH
LWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKD
KRRRISATTNLSERQVTIWFQNRRVKEKKVINKLKTTS*
a.a.
length
InterPro Name
length(57), motif(79:135) 57IPR022067Homeobox protein Hox1A3 N-terminal [Domain]
length(101), motif(124:224) 101IPR022067Homeobox protein Hox1A3 N-terminal [Domain]
length(77), motif(303:379) 77IPR009057Homeodomain-like [Domain]
length(69), motif(312:380) 69IPR009057Homeodomain-like [Domain]
length(61), motif(320:380) 61IPR001356Homeobox domain [Domain]
length(63), motif(322:384) 63IPR001356Homeobox domain [Domain]
length(57), motif(323:379) 57IPR001356Homeobox domain [Domain]
length(24), motif(355:378) 24IPR017970Homeobox, conserved site [Conserved_site]

Protein function information
H-Inv protein ID HIP000105531
Representative H-Inv transcript ID Transcript view HIT000265606
H-Inv cluster ID Locus view HIX0201189
Definition Homeobox protein Hox-A13; Homeobox protein Hox-1J;
Similarity category Help Identical to known human protein(Category I).
Identical to known human protein (P31271) [Identity/coverage = 99.742%/100.0%] to Homo sapiens (Human). protein.
Gene family/group H-Inv gene family/group ID HIF0000005
Gene family/group name Zinc finger, C2H2-type (IPR007087).
Evidence motif (InterPro) ID 3
EC number NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
UniProt NA
CCDS NA
Gene symbol/name HGNC symbol NA
HGNC aliases NA
HGNC name NA
Related H-InvDB links G-integraG-integra ; PPI viewer PPI view ; TACT TACT ;

Glycosylation
GPDB (GlycoProtDB)
GPDB
ID NA
Protein name NA
Organism NA
Length(aa) NA

Subcellular localization information
WoLF PSORT nuclear;
Target P Not predicted
SOSUI soluble protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified : 27-May-2015
Start End PDB_ID E-value Identity Coverage SCOP_ID
311 378 1mnmC 5e-16 26.5 68/77 a.4.1.1
Related H-InvDB links GTOP GTOP

Evolutionary information
Relationship Species Accession number MGI Links
Orthology Danio sp. (Zebrafish) BC090761 G-integraG-integra
Orthology Bos sp. (Cow) ENSBTAT00000046051 G-integraG-integra
Orthology Canis sp. (Dog) ENSCAFT00000004756 G-integraG-integra
Orthology Gallus sp. (Chicken) ENSGALT00000037816 G-integraG-integra
Orthology Mus sp. (Mouse) ENSMUST00000047993 G-integraG-integra
Orthology Oryzias sp. (Medaka) ENSORLT00000006356 G-integraG-integra
Orthology Pongo sp. (Orangutan) ENSPPYT00000020620 G-integraG-integra
Orthology Rattus sp. (Rat) ENSRNOT00000010441 G-integraG-integra
Orthology Tetraodon sp. (Tetraodon) GSTENT00020457001 G-integraG-integra
Orthology Takifugu sp. (Fugu) SINFRUT00000179640 G-integraG-integra
Orthology Monodelphis sp. (Opossum) XM_001362439 G-integraG-integra
Orthology Pan sp. (Chimpanzee) XM_527701 G-integraG-integra
Phylogenetic tree [View by ATV] TNeighbor-joining (phb) 
Related H-InvDB links EvolaEvola dN/dS

Translation polymorphism (SNP) and microsatellite (STR) information

Single Nucleotide Polymorphism (SNP) and indel VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
75..75 G/A rs200676634 - CDS Nonsynonymous[Val16Ile]
176..176 G/A rs35042646 + CDS Synonymous[Ala49Ala]
450^451 -/AGGCGGGCC rs35599078 + CDS
525..525 C/A rs34398255 + CDS Nonsynonymous[Pro166Thr]
533..533 G/A rs34185333 + CDS Synonymous[Ala168Ala]
626..626 G/T/A rs35255035 - CDS
662..662 G/T rs35277569 + CDS Nonsynonymous[Met211Ile]
670..670 C/A rs150062376 - CDS Nonsynonymous[Ala214Asp]
691..691 T/A rs139336802 - CDS Nonsynonymous[Phe221Tyr]
697..697 C/G rs41311757 - CDS Nonsynonymous[Ser223Cys]
702..702 G/C rs151310409 - CDS Nonsynonymous[Ala225Pro]
713..713 C/T rs201761598 - CDS Synonymous[Phe228Phe]
716..716 C/G rs1065462 + CDS Synonymous[Ala229Ala]
813..813 G/A rs61737504 - CDS Nonsynonymous[Gly262Ser]
846..846 A/G rs139880902 - CDS Nonsynonymous[Met273Val]
888..888 G/A rs145935388 - CDS Nonsynonymous[Gly287Ser]
915..915 G/C rs199871426 - CDS Nonsynonymous[Ala296Pro]
926..926 C/T rs183941484 - CDS Synonymous[Pro299Pro]
944..944 T/G rs200379258 - CDS Synonymous[Thr305Thr]
953..953 C/A rs142315866 - CDS Nonsynonymous[Asp308Glu]
957..957 G/A rs112749872 - CDS Nonsynonymous[Val310Ile]
979..979 G/C rs139120665 - CDS Nonsynonymous[Ser317Thr]
982..982 C/G rs146259736 - CDS Nonsynonymous[Ser318Cys]
991..991 G/A rs76529896 - CDS Nonsynonymous[Arg321Lys]
994^995 -/G rs11386833 - CDS
1031..1031 A/G rs35608915 + CDS Synonymous[Leu334Leu]
1052..1052 C/T rs138584447 - CDS Synonymous[Tyr341Tyr]
1105..1105 C/T rs149615551 - CDS Nonsynonymous[Thr359Met]
1136..1136 G/A rs104894019 + CDS AA-STOP[Trp369*]
1143..1143 A/C rs121912542 + CDS Nonsynonymous[Asn372His]
1170^1171 -/G rs66586358 - CDS
Microsatellite (Short Tandem Repeat, STR)
LocationVariationStrand
No data available
Related H-InvDB links
VaryGeneVaryGene ;