H-InvDB x AHG DB
Protein view
H-InvDB_9.0 released on May 27, 2015.
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H-Inv protein ID: HIP000119162 Last modified: 27-May-2015
Definition: Similar to CREB-regulated transcription coactivator 2; Transducer of regulated cAMP response element-binding protein 2; TORC-2; Transducer of CREB protein 2;
[Summery][Full]
[Protein Info][Member][Motif] 
provide location, ID and descriptions of functional motifs (InterPro)[Function] 
provide human-curated functional definition, similarity
category and related evidences;  Gene name; 
HUGO gene symbols; GO term; EC number; pathway information (KEGG)[PTM][Subcellular loc.] 
provide subcellular localization prediction by WolfPSORT, Target P, SOSUI, TMHMM and PTS1[Protein Structure][Evolutionary info.] 
provide orthologs relationships, phylogenic trees and sequence alignments[Polymorphism/repeat] 
provide polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information

Protein information
HIP ID HIP000119162
Length 157
Codon Adaptation Index (CAI). 0.803
Database links RefSeq NA
UniProt NA
CCDS NA
Original transcript information
Representative H-Inv transcript ID Transcript view HIT000091666
H-Inv cluster ID Locus view HIX0001094
Predicted CDS 3..476 ; 157[aa] ; Orientation:+3 ;
Genomic location Chromosome 1
Location 1q21.3
CDS position 153920153-153921658
Strand -
Accession number BC028886.1
CAGE tag ID NA
EST ID NA
Clone Number IMAGE:4500140
Experimental resources NBRC: NITE Biological Resource Center NBRC     Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (CRTC2) ;   Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (CRTC2) ;
Length of cDNA 931[bp] (No. of exon:3)[A:219 T:205 G:256 C:251] ;
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:200186 ;
KEGG GENES KEGG GENES(200186) ;
GeneCard GeneCard CRTC2 ;
etc H-GOLD Human-Gene diversity Of Life-style related Diseases ;
Protein view


Coresponding transcript member (s)
No.1
H-Inv IDTranscript view HIT000091666
H-Inv cluster IDLocus view HIX0001094
Accession numberBC028886.1
CAGE tag IDNA
EST IDNA
Coding potential Help Protein coding
DefinitionSimilar to CREB-regulated transcription coactivator 2; Transducer of regulated cAMP response element-binding protein 2; TORC-2; Transducer of CREB protein 2;
Similarity category HelpSimilar to known protein(Category II).
Similar to known protein (Q53ET0) [Identity/coverage = 100.0%/22.66%] to Homo sapiens (Human). protein.
Transcript feature Help NA
Genomic Location G-integra Help Chromosome1
Location1q21.3
CDS position153920153-153921658
Strand-
Gene structure3 exons

Motif information in predicted CDS
ORF

length(158),orf(3:476)
PGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLG
GEGPMGGPQDPHTFNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALA
GVPGFEVSAAGLELGLGLEDELRMEPLGLEGLNMLSDPCALLPDPAVEES
FRSDRLQ*
a.a.
length
InterPro Name
length(157), motif(1:157) 157IPR024786Transducer of regulated CREB activity [Family]
length(78), motif(79:156) 78IPR024785Transducer of regulated CREB activity, C-terminal [Domain]

Protein function information
H-Inv protein ID HIP000119162
Representative H-Inv transcript ID Transcript view HIT000091666
H-Inv cluster ID Locus view HIX0001094
Definition Similar to CREB-regulated transcription coactivator 2; Transducer of regulated cAMP response element-binding protein 2; TORC-2; Transducer of CREB protein 2;
Similarity category Help Similar to known protein(Category II).
Similar to known protein (Q53ET0) [Identity/coverage = 100.0%/22.66%] to Homo sapiens (Human). protein.
Gene family/group H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
EC number NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
UniProt NA
CCDS NA
Gene symbol/name HGNC symbol CRTC2
HGNC aliases NA
HGNC name CREB regulated transcription coactivator 2;
Related H-InvDB links G-integraG-integra ; PPI viewer PPI view ; TACT TACT ;

Glycosylation
GPDB (GlycoProtDB)
GPDB
ID NA
Protein name NA
Organism NA
Length(aa) NA

Subcellular localization information
WoLF PSORT nuclear;
Target P Not predicted
SOSUI soluble protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Translation polymorphism (SNP) and microsatellite (STR) information

Single Nucleotide Polymorphism (SNP) and indel VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
38..38 C/T rs201931769 - CDS Synonymous[His12His]
40..40 G/A rs200773596 - CDS Nonsynonymous[Arg13Gln]
46..46 T/A rs200292489 - CDS Nonsynonymous[Met15Lys]
104..104 C/G rs201098465 - CDS Nonsynonymous[Ser34Arg]
135..135 G/A rs187465892 - CDS Nonsynonymous[Gly45Arg]
256..256 G/A rs202045208 - CDS Nonsynonymous[Gly85Glu]
263..263 C/G rs138486317 - CDS Synonymous[Ser87Ser]
291..291 G/A rs199941170 - CDS Nonsynonymous[Ala97Thr]
302..302 C/T rs138788943 - CDS Synonymous[Ala100Ala]
303..303 G/A rs140933480 - CDS Nonsynonymous[Gly101Arg]
308..308 G/A rs141962023 - CDS Synonymous[Val102Val]
321..321 G/A rs182932650 - CDS Nonsynonymous[Val107Met]
338..338 G/A rs200008976 - CDS Synonymous[Leu112Leu]
346..346 G/A rs141409588 - CDS Nonsynonymous[Gly115Glu]
364..364 A/C rs199719013 - CDS Nonsynonymous[Glu121Ala]
369..369 C/T rs149096848 - CDS Nonsynonymous[Arg123Cys]
473..473 A/G rs201718464 - CDS Synonymous[Gln157Gln]
Microsatellite (Short Tandem Repeat, STR)
LocationVariationStrand
No data available
Related H-InvDB links
VaryGeneVaryGene ;