H-InvDB x AHG DB
Protein view
H-InvDB_9.0 released on May 27, 2015.
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H-Inv protein ID: HIP000141877 Last modified: 27-May-2015
Definition: Similar to Presenilin-2; PS-2; EC=3.4.23.-; AD3LP; AD5; E5-1; STM-2; Contains: Presenilin-2 NTF subunit; Contains: Presenilin-2 CTF subunit;
[Summery][Full]
[Protein Info][Member][Motif] 
provide location, ID and descriptions of functional motifs (InterPro)[Function] 
provide human-curated functional definition, similarity
category and related evidences;  Gene name; 
HUGO gene symbols; GO term; EC number; pathway information (KEGG)[PTM][Subcellular loc.] 
provide subcellular localization prediction by WolfPSORT, Target P, SOSUI, TMHMM and PTS1[Protein Structure][Evolutionary info.] 
provide orthologs relationships, phylogenic trees and sequence alignments[Polymorphism/repeat] 
provide polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information

Protein function information
H-Inv protein ID HIP000141877
Representative H-Inv transcript ID Transcript view HIT000219377
H-Inv cluster ID Locus view HIX0001647
Definition Similar to Presenilin-2; PS-2; EC=3.4.23.-; AD3LP; AD5; E5-1; STM-2; Contains: Presenilin-2 NTF subunit; Contains: Presenilin-2 CTF subunit;
Similarity category Help Similar to known protein(Category II).
Similar to known protein (P49810) [Identity/coverage = 99.767%/96.21%] to Homo sapiens (Human). protein.
Gene family/group H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
EC number EC 3.4.23.- Aspartic endopeptidases
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer No. of interaction 2
Interaction partner(s) HIP000028058; HIP000059101;
BIND 177583; 177584; 177585; 177765; 177778; 177779;
DIP NA
MINT MINT-13994; MINT-13995; MINT-14379; MINT-14380; MINT-14945; MINT-14946; MINT-14947; MINT-15560; MINT-15561; MINT-15562; MINT-16270; MINT-16271; MINT-16272; MINT-17115; MINT-17116; MINT-17615; MINT-17616; MINT-17617;
HPRD 00100; 00253; 00277; 00286; 00977; 01290; 01680; 01827; 02060; 02497; 02524; 02606; 02607; 02739; 02799; 02920; 03188; 03321; 03457; 03459; 03509; 03800; 04543; 04671; 05198; 05232; 05440; 05584; 05715; 06360; 06361; 06362; 06907; 09063; 09181; 09705; 10216; 10341; 10549; 11517; 12184; 12363; 17469;
IntAct NA
Database links RefSeq NA
UniProt NA
CCDS NA
Gene symbol/name HGNC symbol PSEN2
HGNC aliases "Alzheimer disease 4";
HGNC name presenilin 2;
Related H-InvDB links G-integraG-integra ; PPI viewer PPI view ; TACT TACT ;