H-InvDB_9.0 released on May 27, 2015. Search by Keyword H-Inv ID (HIT) H-Inv cluster ID (HIX) H-Inv protein ID (HIP) H-Inv gene family/group (HIF) Accession number Chromosome number Chromosome band Definition* Data source ID --- CCDS ID dbSNP ID (rs number) EC number Ensembl ID EntrezGene ID FR ID FR Accession number GO ID GO name* HGNC gene symbol HGNC gene name* InterPro ID InterPro name* OMIM ID OMIM title* Pathway ID Pathway name* RefSeq (gene) ID RefSeq (protein) ID SCOP ID UniProt for Advanced Search

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H-Inv protein ID:	HIP000177746	Last modified:	27-May-2015
Definition:	Similar to Alpha-enolase; EC=4.2.1.11; 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding protein;

Select FormatXML fileFlat fileProtein sequence fasta

Protein information HIP ID HIP000177746 Length 166 Codon Adaptation Index (CAI). 0.767 Database links RefSeq NA UniProt NA CCDS NA Original transcript information Representative H-Inv transcript ID HIT000394748 H-Inv cluster ID HIX0000101 Predicted CDS 3..500 ; 166[aa] ; Orientation:+3 ; Genomic location Chromosome 1 Location 1p36.23 CDS position 8926408-8932033 Strand - Accession number EF036495.1 CAGE tag ID NA EST ID NA Clone Number NA Experimental resources NBRC     Antibody (ENO1) ;   Catalog (ENO1) ; Length of cDNA 500[bp] (No. of exon:5)[A:133 T:110 G:137 C:120] ; Database links RefSeq NA Ensembl NA Entrez Gene Entrez Gene ID:2023 ; KEGG GENES KEGG GENES(2023) ; GeneCard ENO1 ; etc Human-Gene diversity Of Life-style related Diseases ;

AVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEK

Coresponding transcript member (s)

No.		1
H-Inv ID		HIT000394748
H-Inv cluster ID		HIX0000101
Accession number		EF036495.1
CAGE tag ID		NA
EST ID		NA
Coding potential		Protein coding
Definition		Similar to Alpha-enolase; EC=4.2.1.11; 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding protein;
Similarity category		Similar to known protein(Category II).
		Similar to known protein (P06733) [Identity/coverage = 100.0%/38.25%] to Homo sapiens (Human). protein.
Transcript feature		NA
Genomic Location	Chromosome	1
	Location	1p36.23
	CDS position	8926408-8932033
	Strand	-
Gene structure		5 exons

Motif information in predicted CDS

	a.a. length	InterPro	Name
	93	IPR029017	Enolase N-terminal domain-like [Domain]
	101	IPR020811	Enolase, N-terminal [Domain]
	104	IPR029017	Enolase N-terminal domain-like [Domain]
	166	IPR000941	Enolase [Family]
	15	IPR000941	Enolase [Family]
	17	IPR000941	Enolase [Family]
	72	IPR029065	Enolase C-terminal domain-like [Domain]
	57	IPR020810	Enolase, C-terminal [Domain]
	57	IPR029065	Enolase C-terminal domain-like [Domain]
	14	IPR000941	Enolase [Family]

Protein function information

H-Inv protein ID		HIP000177746
Representative H-Inv transcript ID		HIT000394748
H-Inv cluster ID		HIX0000101
Definition		Similar to Alpha-enolase; EC=4.2.1.11; 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding protein;
Similarity category		Similar to known protein(Category II).
		Similar to known protein (P06733) [Identity/coverage = 100.0%/38.25%] to Homo sapiens (Human). protein.
Gene family/group	H-Inv gene family/group ID	NA
	Gene family/group name	NA
	Evidence motif (InterPro) ID	NA
EC number		EC 4.2.1.11 phosphopyruvate hydratase
KEGG metabolic pathway		00010 Glycolysis / Gluconeogenesis 00400 Phenylalanine, tyrosine and tryptophan biosynthesis
Protein-protein interaction (PPI)	No. of interaction	NA
	Interaction partner(s)	NA
	BIND	NA
	DIP	NA
	MINT	NA
	HPRD	NA
	IntAct	NA
Database links	RefSeq	NA
	UniProt	NA
	CCDS	NA
Gene symbol/name	HGNC symbol	ENO1
	HGNC aliases	NA
	HGNC name	enolase 1, (alpha);
Related H-InvDB links		G-integra ; PPI view ; TACT ;

Glycosylation GPDB (GlycoProtDB) ID NA Protein name NA Organism NA Length(aa) NA

Subcellular localization information WoLF PSORT cytosol; Target P Other SOSUI soluble protein TMHMM soluble protein PTS1 Not targeted Related H-InvDB links LIFEdb;  JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Translation polymorphism (SNP) and microsatellite (STR) information

Single Nucleotide Polymorphism (SNP) and indel Location Variation dbSNP ID Strand CDS/UTR Translation 28..28 G/C rs11544503 + CDS Nonsynonymous[Gly9Ala] 34..34 A/G rs138834005 - CDS Nonsynonymous[Tyr11Cys] 70..70 G/A rs201990176 - CDS Nonsynonymous[Arg23His] 78..78 G/A rs142310173 - CDS Nonsynonymous[Gly26Arg] 104..104 G/A rs28999074 + CDS Synonymous[Glu34Glu] 107..107 C/T rs201513751 - CDS Synonymous[His35His] 112..112 A/G rs201867667 - CDS Nonsynonymous[Asn37Ser] 126..126 C/A rs146938354 - CDS Nonsynonymous[Pro42Thr] 134..134 G/A rs28999075 + CDS Synonymous[Leu44Leu] 135..135 G/T rs146619828 - CDS Nonsynonymous[Val45Phe] 185..185 G/C rs11544491 + CDS Nonsynonymous[Met61Ile] 196..196 A/G rs201943492 - CDS Nonsynonymous[Asp65Gly] 227..227 G/A rs200935067 - CDS Synonymous[Ala75Ala] 255..255 G/A rs199529530 - CDS Nonsynonymous[Val85Ile] 260..260 C/T rs11544507 + CDS Synonymous[Cys86Cys] 273..273 G/A/C rs11544519 + CDS 299^300 -/CC rs144538182 - CDS 302..302 C/T rs11544497 + CDS Synonymous[His100His] 320..320 C/A rs142256351 - CDS Synonymous[Gly106Gly] 398..398 G/C rs11544509 + CDS Nonsynonymous[Met132Ile] 434..434 C/A/T rs11544513 + CDS 470..470 C/T rs11544499 + CDS Synonymous[Tyr156Tyr] 472..472 A/G rs201627070 - CDS Nonsynonymous[His157Arg] 489..489 A/G rs199771237 - CDS Nonsynonymous[Ile163Val] Microsatellite (Short Tandem Repeat, STR) Location Variation Strand No data available Related H-InvDB links VaryGene ;