H-InvDB x AHG DB
Protein view
H-InvDB_9.0 released on May 27, 2015.
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H-Inv protein ID: HIP000285386 Last modified: 27-May-2015
Definition: Similar to Abelson tyrosine-protein kinase 2 isoform h.
[Summery][Full]
[Protein Info][Member][Motif] 
provide location, ID and descriptions of functional motifs (InterPro)[Function] 
provide human-curated functional definition, similarity
category and related evidences;  Gene name; 
HUGO gene symbols; GO term; EC number; pathway information (KEGG)[PTM][Subcellular loc.] 
provide subcellular localization prediction by WolfPSORT, Target P, SOSUI, TMHMM and PTS1[Protein Structure][Evolutionary info.] 
provide orthologs relationships, phylogenic trees and sequence alignments[Polymorphism/repeat] 
provide polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information

Protein function information
H-Inv protein ID HIP000285386
Representative H-Inv transcript ID Transcript view HIT000558720
H-Inv cluster ID Locus view HIX0001374
Definition Similar to Abelson tyrosine-protein kinase 2 isoform h.
Similarity category Help Similar to known protein(Category II).
Similar to known protein (NP_001161710) [Identity/coverage = 95.841%/100.0%] to Homo sapiens protein.
Gene family/group H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
EC number EC 2.7.10.2 non-specific protein-tyrosine kinase
KEGG metabolic pathway 04020 Calcium signaling pathway 04360 Axon guidance 04370 VEGF signaling pathway 04510 Focal adhesion 04520 Adherens junction 04530 Tight junction 04540 Gap junction 04630 Jak-STAT signaling pathway 04660 T cell receptor signaling pathway 04662 B cell receptor signaling pathway 04664 Fc epsilon RI signaling pathway 04670 Leukocyte transendothelial migration 04730 Long-term depression 04810 Regulation of actin cytoskeleton 04912 GnRH signaling pathway 04920 Adipocytokine signaling pathway 05120 Epithelial cell signaling in Helicobacter pylori infection 05130 Pathogenic Escherichia coli infection - EHEC 05131 Pathogenic Escherichia coli infection - EPEC
Protein-protein interaction (PPI) PPI viewer No. of interaction 16
Interaction partner(s) HIP000008212; HIP000021733; HIP000022718; HIP000026075; HIP000030971; HIP000033435; HIP000041738; HIP000046292; HIP000066345; HIP000075375; HIP000083211; HIP000083789; HIP000085283; HIP000102704; HIP000106185; HIP000157576;
BIND NA
DIP NA
MINT NA
HPRD 00282; 00796; 01044; 01267; 01809; 02997; 05813; 12473; 16124;
IntAct NA
Database links RefSeq NA
UniProt NA
CCDS
Gene symbol/name HGNC symbol ABL2
HGNC aliases "v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)", "v-abl Abelson murine leukemia viral oncogene homolog 2", "c-abl oncogene 2, non-receptor tyrosine kinase";
HGNC name ABL proto-oncogene 2, non-receptor tyrosine kinase;
Related H-InvDB links G-integraG-integra ; PPI viewer PPI view ; TACT TACT ;