H-InvDB_9.0 released on May 27, 2015.
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H-Inv ID (HIT)
H-Inv cluster ID (HIX)
H-Inv protein ID (HIP)
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Definition*
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---
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H-Inv cluster ID:
HIX0010441
Created date:
26-Mar-2013
Last modified:
27-May-2015
Definition:
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Select format
Flat file
XML file
Gene structure
H-Inv cluster ID
HIX0010441
Genomic location
Chromosome
12
Location
12p13.1
Position
12867992- 12875305
Strand
+
Antisense cluster ID(s)
NA
Database links
RefSeq
NA
Ensembl
NA
Entrez Gene
Entrez Gene ID:1027
;
KEGG GENES
KEGG GENES(1027)
;
GeneCard
CDKN1B
;
*GeneCards is provided free to academic non-profit institutions.
etc
Human-Gene diversity Of Life-style related Diseases
;
Cluster member H-Inv ID(s)
HIT000431327
;
HIT000030796
;
HIT000218019
;
HIT000487504
;
HIT000268249
;
HIT000487636
;
HIT000492959
;
HIT000082768
;
HIT000074953
;
HIT000266550
;
HIT000266551
;
HIT000249231
;
Additional cluster member candidate(s)
NA
Related H-InvDB links
H-DBAS
;
G-integra
;
cDNA-genome multiple alignment
;
ORF multiple alignment
;
TOP
1-10
11-12
LAST
Cluster member (s)
Locus member number
1
H-Inv ID
HIT000431327
Accession number
AK312461.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
Representative transcript;
Genomic location
Chromosome
12
Location
12p13.1
Position
12870302- 12871880
Strand
+
Gene structure
2 exons
TOP
1-10
11-12
LAST
Locus member number
2
H-Inv ID
HIT000030796
Accession number
BC001971.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 99.495%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
Splicing isoform
Genomic location
Chromosome
12
Location
12p13.1
Position
12870397- 12875303
Strand
+
Gene structure
3 exons
TOP
1-10
11-12
LAST
Locus member number
3
H-Inv ID
HIT000218019
Accession number
U10906.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
NA
Genomic location
Chromosome
12
Location
12p13.1
Position
12870774- 12871880
Strand
+
Gene structure
2 exons
TOP
1-10
11-12
LAST
Locus member number
4
H-Inv ID
HIT000487504
Accession number
AB451291.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
NA
Genomic location
Chromosome
12
Location
12p13.1
Position
12870774- 12871880
Strand
+
Gene structure
2 exons
TOP
1-10
11-12
LAST
Locus member number
5
H-Inv ID
HIT000268249
Accession number
CR457399.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
NA
Genomic location
Chromosome
12
Location
12p13.1
Position
12870774- 12871880
Strand
+
Gene structure
2 exons
TOP
1-10
11-12
LAST
Locus member number
6
H-Inv ID
HIT000487636
Accession number
AB451423.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
NA
Genomic location
Chromosome
12
Location
12p13.1
Position
12870774- 12871877
Strand
+
Gene structure
2 exons
TOP
1-10
11-12
LAST
Locus member number
7
H-Inv ID
HIT000492959
Accession number
AK298335.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Similar to Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Similar to known protein(Category II).
Similar to known protein (
P46527
) [Identity/coverage = 100.0%/86.87%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
Splicing isoform
Genomic location
Chromosome
12
Location
12p13.1
Position
12870404- 12874690
Strand
+
Gene structure
4 exons
TOP
1-10
11-12
LAST
Locus member number
8
H-Inv ID
HIT000082768
Accession number
AY004255.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 98.99%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
NA
Genomic location
Chromosome
12
Location
12p13.1
Position
12870622- 12875302
Strand
+
Gene structure
3 exons
TOP
1-10
11-12
LAST
Locus member number
9
H-Inv ID
HIT000074953
Accession number
AF247551.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 99.495%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
NA
Genomic location
Chromosome
12
Location
12p13.1
Position
12870774- 12871880
Strand
+
Gene structure
2 exons
TOP
1-10
11-12
LAST
Locus member number
10
H-Inv ID
HIT000266550
Accession number
BT019553.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 99.495%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
NA
Genomic location
Chromosome
12
Location
12p13.1
Position
12870774- 12871879
Strand
+
Gene structure
2 exons
TOP
1-10
11-12
LAST
Locus member number
11
H-Inv ID
HIT000266551
Accession number
BT019554.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 99.495%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
NA
Genomic location
Chromosome
12
Location
12p13.1
Position
12870774- 12871879
Strand
+
Gene structure
2 exons
TOP
1-10
11-12
LAST
Locus member number
12
H-Inv ID
HIT000249231
Accession number
AJ616234.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Similar to Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Similar to known protein(Category II).
Similar to known protein (
P46527
) [Identity/coverage = 98.529%/68.69%] to Homo sapiens (Human). protein.
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Transcript feature
NA
Genomic location
Chromosome
12
Location
12p13.1
Position
12870780- 12871188
Strand
+
Gene structure
1 exons
Alternative splicing (AS) information
Pattern of alternative splicing isoforms
5' terminal AS; Internal AS;
Position of alternative splicing isoforms
Retained intron;
Alternative splicing isoform H-Inv ID(s)
HIT000492959
;
HIT000030796
;
Related H-InvDB links
H-DBAS
;
G-integra
;
cDNA-genome multiple alignment
;
ORF multiple alignment
;
Gene function information
H-Inv cluster ID
HIX0010441
Representative H-Inv ID
HIT000431327
Accession number
AK312461.1
CAGE tag ID
NA
EST ID
NA
Coding potential
Protein coding;
Definition
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P46527
) [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene family/group
H-Inv gene family/group ID
NA
Gene family/group name
NA
Evidence motif (InterPro) ID
NA
Gene symbol/name
HGNC symbol
CDKN1B
HGNC aliases
NA
HGNC name
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Protein-protein interaction (PPI)
H-Inv protein ID
HIP000100966
No. of interaction
25
Interaction partner(s)
HIP000002556
;
HIP000017384
;
HIP000022530
;
HIP000022927
;
HIP000023977
;
HIP000024198
;
HIP000024198
;
HIP000024246
;
HIP000027757
;
HIP000031541
;
HIP000031618
;
HIP000035485
;
HIP000036897
;
HIP000036938
;
HIP000041479
;
HIP000041967
;
HIP000049338
;
HIP000059140
;
HIP000069035
;
HIP000072950
;
HIP000082461
;
HIP000097495
;
HIP000099393
;
HIP000253216
;
HIP000349437
;
BIND
149092; 182282; 182285; 182628; 197221; 197224; 197289; 197292; 74538; 74539;
DIP
102604E; 103851E; 103852E; 132729E; 152943E; 549E; 550E; 552E; 553E; 556E; 61897E; 63231E;
MINT
MINT-17679; MINT-17680; MINT-1779946; MINT-1779996; MINT-17888; MINT-17889; MINT-3379700; MINT-3379718; MINT-63858; MINT-67874; MINT-68420; MINT-7219650; MINT-7993413; MINT-8006094; MINT-8007803; MINT-8008250; MINT-8008504; MINT-8008511;
HPRD
00150; 00215; 00299; 00447; 00449; 00451; 00452; 00453; 00454; 00455; 00886; 00961; 01047; 01154; 01261; 01285; 01301; 01323; 01346; 01809; 01819; 01850; 01877; 02440; 02818; 03109; 03184; 03256; 03402; 03459; 03536; 03538; 03565; 03975; 04114; 04389; 04533; 04801; 04946; 05179; 05226; 05457; 05639; 06771; 06794; 06888; 07218; 12050; 18095;
IntAct
NA
Database links
RefSeq
NA
Ensembl
NA
Entrez Gene
Entrez Gene ID:1027
;
KEGG GENES
KEGG GENES(1027)
;
GeneCard
CDKN1B
;
*GeneCards is provided free to academic non-profit institutions.
etc
Human-Gene diversity Of Life-style related Diseases
;
Related H-InvDB links
G-integra
;
PPI view
;
H-DBAS
;
Gene family;
Similarity search tool
;
TACT
;
Disease/pathology information
Last modified:27-May-2015
Disease relation
Disease name: Multiple endocrine neoplasia, type IV (
610755
);
Related information in OMIM
OMIM ID:
600778
; Title: CYCLIN-DEPENDENT KINASE INHIBITOR 1B
Co-localized orphan diseases
NA
Disease related mutation
MutationView:
600778
;
JRE-1.4.0 or later is required.Download JRE at
Sun's web site.
Co-occurred words and phrases with this gene name in PubMed (LEGENDA)
Gene name
Entrez Gene ID:(1027);
Disease
Entrez Gene ID:(1027);
Gene function
Entrez Gene ID:(1027);
Substance
Entrez Gene ID:(1027);
Related H-InvDB links
DiseaseInfo Viewer
;
LEGENDA
;