H-InvDB x AHG DB
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H-InvDB_9.0 released on May 27, 2015.
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H-Inv cluster ID: HIX0032121 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; AltName: CD_antigen=CD49b; Precursor;
 
 

Gene structure  G-integra H-DBAS
H-Inv cluster ID HIX0032121
Genomic location  G-integra Help Chromosome 5
Location 5q11.2
Position 52285156- 52390609
Strand +
Antisense cluster ID(s) NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:3673
KEGG GENES KEGG GENES(3673)
GeneCard GeneCardITGA2*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Cluster member H-Inv ID(s) HIT000321595HIT000501963HIT000501961HIT000501958HIT000501960HIT000501964HIT000426818
Additional cluster member candidate(s) NA
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA multiple alignmentcDNA-genome multiple alignment ORF multiple alignmentORF multiple alignment
Mini-G Locus map Locus map

 
TOP 1-7 LAST 
Cluster member (s)  G-integra H-DBAS
Locus member number 1
H-Inv ID Transcript viewHIT000321595
Accession number X17033.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; AltName: CD_antigen=CD49b; Precursor;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (P17301)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol ITGA2 
HGNC aliases NA
HGNC name integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 
Transcript feature Representative H-Inv IDRepresentative transcript;  Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 5
Location 5q11.2
Position 52285257- 52388190
Strand +
Gene structure 30 exons
 
TOP 1-7 LAST 
Locus member number 2
H-Inv ID Transcript viewHIT000501963
Accession number BC143511.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; AltName: CD_antigen=CD49b; Precursor;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (P17301)  [Identity/coverage = 99.915%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol ITGA2 
HGNC aliases NA
HGNC name integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 5
Location 5q11.2
Position 52285270- 52386487
Strand +
Gene structure 30 exons
 
TOP 1-7 LAST 
Locus member number 3
H-Inv ID Transcript viewHIT000501961
Accession number BC143509.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Integrin alpha-2 precursor.
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (NP_002194)  [Identity/coverage = 99.915%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol ITGA2 
HGNC aliases NA
HGNC name integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 5
Location 5q11.2
Position 52285270- 52386487
Strand +
Gene structure 30 exons
 
TOP 1-7 LAST 
Locus member number 4
H-Inv ID Transcript viewHIT000501958
Accession number BC143505.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Integrin alpha-2 precursor.
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (NP_002194)  [Identity/coverage = 99.913%/100.0%] to Homo sapiens protein.
Gene symbol/name HGNC symbol ITGA2 
HGNC aliases NA
HGNC name integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 5
Location 5q11.2
Position 52285270- 52386487
Strand +
Gene structure 29 exons
 
TOP 1-7 LAST 
Locus member number 5
H-Inv ID Transcript viewHIT000501960
Accession number BC143508.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; AltName: CD_antigen=CD49b; Precursor;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (P17301)  [Identity/coverage = 99.824%/100.0%] to Homo sapiens (Human). protein.
Gene symbol/name HGNC symbol ITGA2 
HGNC aliases NA
HGNC name integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 5
Location 5q11.2
Position 52285270- 52386483
Strand +
Gene structure 29 exons
 
TOP 1-7 LAST 
Locus member number 6
H-Inv ID Transcript viewHIT000501964
Accession number BC143512.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; AltName: CD_antigen=CD49b; Precursor; Fragment;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (P53710)  [Identity/coverage = 86.416%/95.64%] to Bos taurus (Bovine). protein.
Gene symbol/name HGNC symbol ITGA2 
HGNC aliases NA
HGNC name integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 
Transcript feature Splicing isoformSplicing isoform
Genomic location  G-integra Chromosome 5
Location 5q11.2
Position 52285270- 52386476
Strand +
Gene structure 29 exons
 
TOP 1-7 LAST 
Locus member number 7
H-Inv ID Transcript viewHIT000426818
Accession number AK307952.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Similar to Integrin alpha-2 precursor.
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (NP_002194)  [Identity/coverage = 100.0%/98.14%] to Homo sapiens protein.
Gene symbol/name HGNC symbol ITGA2 
HGNC aliases NA
HGNC name integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 
Transcript feature NA
Genomic location  G-integra Chromosome 5
Location 5q11.2
Position 52285167- 52385892
Strand +
Gene structure 29 exons

Alternative splicing (AS) information  G-integra H-DBAS
Pattern of alternative splicing isoforms Internal AS; 
Position of alternative splicing isoforms Cassette;  Internal acceptor site; 
Alternative splicing isoform H-Inv ID(s) Splicing isoformHIT000501958Splicing isoformHIT000501963Splicing isoformHIT000501964Splicing isoformHIT000501960Splicing isoformHIT000501961Splicing isoformHIT000321595
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA multiple alignmentcDNA-genome multiple alignment ORF multiple alignmentORF multiple alignment

Gene function information  G-integra PPI viewer H-DBAS Gene family Similarity Search Tool TACT
H-Inv cluster ID HIX0032121
Representative H-Inv ID Representative H-Inv IDHIT000321595
Accession number X17033.1
CAGE tag ID NA
EST ID NA
Coding potential Protein coding; 
Definition Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; AltName: CD_antigen=CD49b; Precursor;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (P17301)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol ITGA2 
HGNC aliases NA
HGNC name integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000058965
No. of interaction 7
Interaction partner(s) HIP000032912HIP000059359HIP000059673HIP000071861HIP000093682HIP000097919HIP000436453
BIND 177864;  178031;  178218;  24518; 
DIP 10824E;  709E; 
MINT MINT-1894979;  MINT-1895068;  MINT-4301430;  MINT-4792053; 
HPRD 00015;  00016;  00030;  00031;  00062;  00362;  00363;  00372;  00384;  00613;  00628;  00804;  00880;  01033;  03625;  03800;  03892;  05448; 
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:3673
KEGG GENES KEGG GENES(3673)
GeneCard GeneCardITGA2*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Related H-InvDB links G-integraG-integra PPI viewerPPI view H-DBASH-DBAS Gene familyGene family;  Similarity Search ToolSimilarity search tool TACTTACT
Gene expression information   H-ANGEL DNAProbeLocator Last modified:27-May-2015
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator
AceGene AGhsA211522; 
Affymetrix
GeneChip
HG-Focus 205032_at; 
HG-U133 205032_at; 
HG-U133A 205032_at; 
HG-U133A_2 205032_at; 
HG-U133B NA
HG-U133_Plus_2 205032_at; 
HG-U95 1978_at;  41481_at; 
HG-U95A 1978_at;  41481_at; 
HG-U95B NA
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 2809246;  2809247;  2809256;  2809263;  2809268;  2809269;  2809271;  2809272;  2809273;  2809274;  2809275;  2809276;  2809277;  2809278;  2809279;  2809280;  2809281;  2809283;  2809284;  2809285;  2809286;  2809287;  2809290;  2809291;  2809292;  2809294;  2809295;  2809296;  2809297;  2809298;  2809299;  2809301;  2809302;  2856472;  2856474;  2856476; 
HuGeneFL M28249_at; 
Agilent Human 1A Oligo Microarray:PGID215 A_23_P70161; 
Whole Human Genome Oligo Microarray:PGID247 A_23_P70161;  A_24_P243329; 
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Disease/pathology information  DiseaseInfo Viewer LEGENDA Last modified:27-May-2015
Disease relation Disease name:NA
Related information in OMIM OMIM ID:  192974;  Title: INTEGRIN, ALPHA-2
Co-localized orphan diseases NA
Disease related mutation NA
Co-occurred words and phrases with this gene name in PubMed (LEGENDA) LEGENDA Gene name Entrez Gene ID:(3673); 
Disease Entrez Gene ID:(3673); 
Gene function Entrez Gene ID:(3673); 
Substance Entrez Gene ID:(3673); 
Related H-InvDB links DiseaseInfo ViewerDiseaseInfo ViewerLEGENDALEGENDA