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H-InvDB_9.0 released on May 27, 2015.
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H-Invitational ID: HIT000005192 Accession number: AK021918 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Solute carrier family 52, riboflavin transporter, member 2; Porcine endogenous retrovirus A receptor 1; PERV-A receptor 1; Protein GPR172A; Riboflavin transporter 3; hRFT3;
 
 

Transcript original information
Accession number AK021918.1
CAGE tag ID NA
EST ID NA
Clone Number HEMBA1006789
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ; Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (SLC52A2) ; Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (SLC52A2);
Sequence data provider Project:FLJ; Provider:FLJ/HRI; 
Annotation project H-Invitational FLcDNA
Length of cDNA 1830[bp] (No. of exon:6)[A:240 T:388 G:608 C:594]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type whole embryo, mainly head
Develpmental stage embryo, 10 weeks
Mini-G
Sequence quality information
CDS feature Complete CDS
Kozak sequence NA
PolyA NA
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) NA
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0007850
Genomic location  G-integra Help Chromosome 8
Location 8q24.3
Position 145582225- 145584930
Strand +
Possible duplicated location(s) NA
Gene structure 6 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:79581
KEGG GENES KEGG GENES(79581)
GeneCard GeneCardSLC52A2*GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000023220
Predicted CDS 449..1786;  445[aa];  Orientation:+2; 
Codon Adaptation Index (CAI). 0.793
Database links RefSeq NP_001240744NP_001240745NP_078807
UniProt Q9HAB3
CCDS CCDS6423

Motif information
ORF

length(445),orf(449:1786)
MAAPTPARPVLTHLLVALFGMGSWAAVNGIWVELPVVVKELPEGWSLPSY
VSVLVALGNLGLLVVTLWRRLAPGKDEQVPIRVVQVLGMVGTALLASLWH
HVAPVAGQLHSVAFLALAFVLALACCASNVTFLPFLSHLPPRFLRSFFLG
QGLSALLPCVLALVQGVGRLECPPAPINGTPGPPLDFLERFPASTFFWAL
TALLVASAAAFQGLLLLLPPPPSVPTGELGSGLQVGAPGAEEEVEESSPL
QEPPSQAAGTTPGPDPKAYQLLSARSACLLGLLAATNALTNGVLPAVQSF
SCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLGGLSLLGVFCG
GYLMALAVLSPCPPLVGTSAGVVLVVLSWVLCLGVFSYVKVAASSLLHGG
GRPALLAAGVAIQVGSLLGAVAMFPPTSIYHVFHSRKDCADPCDS*
a.a.
length
InterPro Name
length(445), motif(1:445) 445 IPR009357 Endogenous retrovirus receptor [Family]
length(101), motif(271:371) 101 IPR009357 Endogenous retrovirus receptor [Family]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000005192
H-Inv cluster ID Locus viewHIX0007850
Accession number AK021918.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help Representative H-Inv IDRepresentative transcript;  Splicing isoformSplicing isoform
Coding potential  Help Protein coding; 
Definition Solute carrier family 52, riboflavin transporter, member 2; Porcine endogenous retrovirus A receptor 1; PERV-A receptor 1; Protein GPR172A; Riboflavin transporter 3; hRFT3;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (Q9HAB3)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Experimental evidence Protein evidence
PubMed ID 12740431147020391548933416421571193075862046314522740598ALL
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol SLC52A2
HGNC aliases "G protein-coupled receptor 172A"
HGNC name solute carrier family 52 (riboflavin transporter), member 2
DDBJ NA
UniProt SLC52A2
EC number NA
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000023220
No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:79581
KEGG GENES KEGG GENES(79581)
GeneCard GeneCardSLC52A2*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Human curated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
NA


Subcellular localization information  Last modified:27-May-2015
WoLF PSORT plasma membrane; 
Target P signal peptide
SOSUI membrane protein
TMHMM membrane protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Gene expression information  H-ANGEL DNAProbeLocator Last modified:27-May-2015
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator
AceGene NA
Affymetrix
GeneChip
HG-Focus NA
HG-U133 218151_x_at;  222155_s_at; 
HG-U133A 218151_x_at;  222155_s_at; 
HG-U133A_2 218151_x_at;  222155_s_at; 
HG-U133B NA
HG-U133_Plus_2 218151_x_at;  222155_s_at; 
HG-U95 54001_at; 
HG-U95A NA
HG-U95B 54001_at; 
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 3120450;  3120451;  3120452;  3120453;  3120454;  3120455;  3120457;  3120459;  3120460;  3120462;  3158388; 
HuGeneFL NA
Agilent Human 1A Oligo Microarray:PGID215 NA
Whole Human Genome Oligo Microarray:PGID247 NA
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Evolutionary information  Evola Help Last modified:27-May-2015
Relationship Species Accession number MGI Links
Orthology Mus sp. (Mouse) AK142597 MGI:3549762 G-integraG-integra
Orthology Bos sp. (Cow) BC118403 G-integraG-integra
Orthology Rattus sp. (Rat) BC133726 G-integraG-integra
Orthology Danio sp. (Zebrafish) ENSDART00000045675 G-integraG-integra
Orthology Equus sp. (Horse) ENSECAT00000016808 G-integraG-integra
Orthology Macaca sp. (Macaque) ENSMMUT00000010307 G-integraG-integra
Orthology Oryzias sp. (Medaka) ENSORLT00000010071 G-integraG-integra
Orthology Pongo sp. (Orangutan) ENSPPYT00000022124 G-integraG-integra
Orthology Tetraodon sp. (Tetraodon) GSTENT00035286001 G-integraG-integra
Orthology Takifugu sp. (Fugu) SINFRUT00000170607 G-integraG-integra
Orthology Pan sp. (Chimpanzee) XM_001157003 G-integraG-integra
Orthology Monodelphis sp. (Opossum) XM_001371748 G-integraG-integra
Orthology Canis sp. (Dog) XM_532355 G-integraG-integra
Phylogenetic tree [View by ATV]
Neighbor-joining (phb) 
Related H-InvDB links EvolaEvoladN/dS (under constraction); 

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
23 .. 23 C/G rs113099131 + 5'UTR
26 .. 26 G/A rs144713518 + 5'UTR
60 .. 60 C/T rs187464121 + 5'UTR
72 .. 72 C/A rs115940535 + 5'UTR
185 .. 185 G/A rs11546260 + 5'UTR
315 .. 315 C/T rs11546258 + 5'UTR
405 .. 405 C/T rs148535877 + 5'UTR
472 .. 472 T/C rs146942171 + CDS Synonymous[Arg8Arg]
497 .. 497 G/T rs138010981 + CDS Nonsynonymous[Ala17Ser]
531 .. 531 A/G rs141698844 + CDS Nonsynonymous[Asn28Ser]
532 .. 532 T/C rs200102613 + CDS Synonymous[Asn28Asn]
605 .. 605 G/C rs150137023 + CDS Nonsynonymous[Val53Leu]
626 .. 626 C/T rs201213634 + CDS Synonymous[Leu60Leu]
640 .. 640 G/C rs201246554 + CDS Synonymous[Val64Val]
676 .. 676 C/T rs111588500 + CDS Synonymous[Asp76Asp]
757 .. 757 C/T rs146256291 + CDS Synonymous[Ala103Ala]
801 .. 801 C/A rs117500243 + CDS Nonsynonymous[Ala118Asp]
807 .. 807 T/C rs74445699 + CDS Nonsynonymous[Val120Ala]
818 .. 818 G/T rs146274588 + CDS Nonsynonymous[Ala124Ser]
819 .. 819 C/T rs200753132 + CDS Nonsynonymous[Ala124Val]
832 .. 832 G/A rs140003920 + CDS Synonymous[Ser128Ser]
858 .. 858 G/A rs199864300 + CDS Nonsynonymous[Ser137Asn]
926 .. 926 G/A rs141953803 + CDS Nonsynonymous[Val160Met]
946 .. 946 T/C rs146310658 + CDS Synonymous[Gly166Gly]
976 .. 976 C/T rs148530003 + CDS Synonymous[Pro176Pro]
982 .. 982 C/T rs142879103 + CDS Synonymous[Asn178Asn]
983 .. 983 G/A rs151081625 + CDS Nonsynonymous[Gly179Ser]
999 .. 999 C/A rs202232509 + CDS Nonsynonymous[Pro184Gln]
1003 .. 1003 C/T rs74370046 + CDS Synonymous[Leu185Leu]
1016 .. 1016 C/T rs201705744 + CDS Nonsynonymous[Arg190Cys]
1046 .. 1046 C/T rs200455766 + CDS Synonymous[Leu200Leu]
1054 .. 1054 C/T rs187632310 + CDS Synonymous[Ala202Ala]
1061 .. 1061 G/A rs144883729 + CDS Nonsynonymous[Val205Ile]
1091 .. 1091 C/T rs147954962 + CDS Synonymous[Leu215Leu]
1105 .. 1105 G/A rs141909863 + CDS Synonymous[Pro219Pro]
1228 .. 1228 C/T rs200533281 + CDS Synonymous[Thr260Thr]
1270 .. 1270 C/A rs145009003 + CDS Synonymous[Ala274Ala]
1272 .. 1272 G/A rs144912258 + CDS Nonsynonymous[Arg275His]
1366 .. 1366 G/A rs149050347 + CDS Synonymous[Gly306Gly]
1368 .. 1368 G/A rs143091206 + CDS Nonsynonymous[Arg307His]
1464 .. 1464 T/C rs148234606 + CDS Nonsynonymous[Leu339Pro]
1465 .. 1465 G/C rs140307485 + CDS Synonymous[Leu339Leu]
1487 .. 1487 G/A rs145502954 + CDS Nonsynonymous[Val347Met]
1513 .. 1513 G/T rs200618841 + CDS Synonymous[Ala355Ala]
1514 .. 1514 C/T rs138107380 + CDS Synonymous[Leu356Leu]
1522 .. 1522 C/T rs142697341 + CDS Synonymous[Val358Val]
1537 .. 1537 G/A rs146292053 + CDS Synonymous[Pro363Pro]
1554 .. 1554 C/T rs138160033 + CDS Nonsynonymous[Ser369Leu]
1561 .. 1561 G/A rs149575570 + CDS Synonymous[Gly371Gly]
1564 .. 1564 C/G rs200631895 + CDS Synonymous[Val372Val]
1566 .. 1566 T/G rs200245353 + CDS Nonsynonymous[Val373Gly]
1570 .. 1570 C/T rs144290224 + CDS Synonymous[Leu374Leu]
1611 .. 1611 A/G rs148754028 + CDS Nonsynonymous[Tyr388Cys]
1645 .. 1645 C/T rs144821688 + CDS Synonymous[Gly399Gly]
1675 .. 1675 C/T rs147518188 + CDS Synonymous[Gly409Gly]
1687 .. 1687 G/A rs140177553 + CDS Synonymous[Gln413Gln]
1705 .. 1705 C/T rs199767089 + CDS Synonymous[Gly419Gly]
1725 .. 1725 C/T rs201673476 + CDS Nonsynonymous[Pro426Leu]
1741 .. 1741 C/T rs184190914 + CDS Synonymous[His431His]
1742 .. 1742 G/A rs202178971 + CDS Nonsynonymous[Val432Met]
1768 .. 1768 A/G rs189845609 + CDS Synonymous[Ala440Ala]
1769 .. 1769 G/T rs75165898 + CDS Nonsynonymous[Asp441Tyr]
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene Repeat mask viewerRepeat Mask Viewer