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H-InvDB_9.0 released on May 27, 2015.
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H-Invitational ID: HIT000017651 Accession number: AK092784 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Similar to Chaperone activity of bc1 complex-like, mitochondrial; Chaperone-ABC1-like; EC=2.7.11.-; aarF domain-containing protein kinase 3; Precursor;
 
 

Transcript original information
Accession number AK092784.1
CAGE tag ID NA
EST ID NA
Clone Number SMINT2005405
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ; Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (ADCK3) ; Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (ADCK3);
Sequence data provider Project:FLJ; Provider:FLJ/HRI; 
Annotation project H-Invitational FLcDNA
Length of cDNA 2647[bp] (No. of exon:15)[A:569 T:541 G:790 C:747]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type small intestine
Develpmental stage NA
Mini-G
Sequence quality information
CDS feature N-truncated
Kozak sequence NA
PolyA NA
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) NA
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0001648
Genomic location  G-integra Help Chromosome 1
Location 1q42.13
Position 227127995- 227175246
Strand +
Possible duplicated location(s) NA
Gene structure 15 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:56997
KEGG GENES KEGG GENES(56997)
GeneCard GeneCardADCK3*GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000381172
Predicted CDS 157..1839;  560[aa];  Orientation:+1; 
Codon Adaptation Index (CAI). 0.867

Motif information
ORF

length(560),orf(157:1839)
RPCQADPGGRGNPPAALGHRRGADHGGPAPAYVASGPFREAGFPGQASSP
LGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEKARQAKAR
PENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSL
RSEDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDA
FINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFA
AASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPE
GLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFFYVPEIVDEL
CSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQT
DPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETV
RAKSIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKI
HNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAY
SNYCKRQAQQ*
a.a.
length
InterPro Name
length(50), motif(228:277) 50 IPR011009 Protein kinase-like domain [Domain]
length(115), motif(232:346) 115 IPR004147 UbiB domain [Domain]
length(127), motif(309:435) 127 IPR011009 Protein kinase-like domain [Domain]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000017651
H-Inv cluster ID Locus viewHIX0001648
Accession number AK092784.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help NO;  Splicing isoformSplicing isoform
Coding potential  Help Protein coding; 
Definition Similar to Chaperone activity of bc1 complex-like, mitochondrial; Chaperone-ABC1-like; EC=2.7.11.-; aarF domain-containing protein kinase 3; Precursor;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q29RI0)  [Identity/coverage = 88.869%/88.12%] to Bos taurus (Bovine). protein.
Experimental evidence Protein evidence
PubMed ID 16305752ALL
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol ADCK3
HGNC aliases "chaperone-ABC1 (activity of bc1 complex, S.pombe)-like", "chaperone, ABC1 activity of bc1 complex like (S. pombe)", "chaperone, ABC1 activity of bc1 complex homolog (S. pombe)"
HGNC name aarF domain containing kinase 3
DDBJ NA
UniProt ADCK3
EC number EC 2.7.11.-Protein-serine/threonine kinases; 
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000381172
No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:56997
KEGG GENES KEGG GENES(56997)
GeneCard GeneCardADCK3*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Auto-annotated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool;  TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
FR ID FR306988
Accession
Description
Location
PMID

Gene ontology information
Molecular function transferase activity, transferring phosphorus-containing groups (GO:0016772); 

Subcellular localization information  Last modified:27-May-2015
WoLF PSORT nuclear;  cytosol;  peroxisome; 
Target P Other
SOSUI soluble protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified:27-May-2015
Start End PDB_ID E-value Identity Coverage SCOP_ID
112 168 1y74A1 2e-21 17.5 57/57 a.194.1.1
160 401 1zylA1 4e-11 10.9 238/325 d.144.1.6
Related H-InvDB links GTOP GTOP

Gene expression information  H-ANGEL DNAProbeLocator Last modified:27-May-2015
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator
AceGene AGhsA241008; 
Affymetrix
GeneChip
HG-Focus NA
HG-U133 218168_s_at;  222542_x_at; 
HG-U133A 218168_s_at; 
HG-U133A_2 218168_s_at; 
HG-U133B 222542_x_at; 
HG-U133_Plus_2 218168_s_at;  222542_x_at; 
HG-U95 45334_at;  64312_at; 
HG-U95A NA
HG-U95B 45334_at; 
HG-U95C 64312_at; 
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 2383379;  2383389;  2383390;  2383391;  2383395;  2383396;  2383404;  2383407;  2383409;  2383411;  2383413;  2383416;  2383419;  2383420;  2383421;  2383422;  2383424;  2383425;  2459040; 
HuGeneFL NA
Agilent Human 1A Oligo Microarray:PGID215 A_23_P85593; 
Whole Human Genome Oligo Microarray:PGID247 A_23_P85598; 
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
119 .. 119 A/G rs199604256 + 5'UTR
129 .. 129 T/A rs202075418 + 5'UTR
153 .. 153 C/T rs200052870 + 5'UTR
168 .. 168 A/G rs150221608 + CDS Synonymous[Gln4Gln]
180 .. 180 C/T rs142184584 + CDS Synonymous[Gly8Gly]
181 .. 181 G/A rs11549709 + CDS Nonsynonymous[Gly9Ser]
185 .. 185 G/A rs35582308 + CDS Nonsynonymous[Arg10His]
196 .. 196 C/T rs150541057 + CDS Nonsynonymous[Pro14Ser]
214 .. 214 C/T rs199919057 + CDS Nonsynonymous[Arg20Trp]
218 .. 218 G/A rs142125927 + CDS Nonsynonymous[Arg21Lys]
279 .. 279 C/T rs139970507 + CDS Synonymous[Ala41Ala]
297 .. 297 C/T rs200182503 + CDS Synonymous[Ala47Ala]
362 .. 362 T/C rs147812454 + CDS Nonsynonymous[Met69Thr]
367 .. 367 T/C rs142652509 + CDS Nonsynonymous[Phe71Leu]
416 .. 416 C/A rs181579601 + CDS Nonsynonymous[Thr87Lys]
420 .. 420 C/T rs201787750 + CDS Synonymous[Ala88Ala]
459 .. 459 C/T rs140897240 + CDS Synonymous[Pro101Pro]
482 .. 482 C/T rs200762439 + CDS Nonsynonymous[Thr109Met]
489 .. 489 C/T rs138547552 + CDS Synonymous[Ser111Ser]
496 .. 496 G/T rs188599627 + CDS Nonsynonymous[Ala114Ser]
500 .. 500 G/A rs145350362 + CDS Nonsynonymous[Arg115Gln]
506 .. 506 G/A rs200541514 + CDS Nonsynonymous[Arg117Gln]
513 .. 513 G/A rs115855910 + CDS Synonymous[Val119Val]
532 .. 532 C/T rs119468005 + CDS Nonsynonymous[Arg126Trp]
574 .. 574 G/A rs199694417 + CDS Nonsynonymous[Gly140Arg]
618 .. 618 C/- rs35757883 + CDS
625 .. 625 G/C rs199619932 + CDS Nonsynonymous[Gly157Arg]
637 .. 637 G/A rs148376283 + CDS Nonsynonymous[Val161Met]
640 .. 640 C/T rs199958142 + CDS Synonymous[Leu162Leu]
675 .. 675 A/G rs147447166 + CDS Synonymous[Ala173Ala]
680 .. 680 G/A rs145422777 + CDS Nonsynonymous[Arg175Gln]
689 .. 689 G/A rs199696414 + CDS Nonsynonymous[Arg178His]
692 .. 692 C/T rs149924675 + CDS Nonsynonymous[Thr179Met]
706 .. 706 C/T rs145034527 + CDS Nonsynonymous[Arg184Cys]
710 .. 710 G/A/T rs119468006 + CDS
749 .. 749 A/C rs143493998 + CDS Nonsynonymous[Asp198Ala]
768 .. 768 C/T rs200849486 + CDS Synonymous[Pro204Pro]
771 .. 771 C/G rs200155917 + CDS Nonsynonymous[His205Gln]
786 .. 786 C/T rs55968053 + CDS Synonymous[Phe210Phe]
790 .. 790 C/T rs201908721 + CDS Nonsynonymous[Arg212Trp]
796 .. 796 C/T rs140246430 + CDS Nonsynonymous[Arg214Trp]
804 .. 804 C/T rs202036077 + CDS Synonymous[Ser216Ser]
843 .. 843 C/T rs55637780 + CDS Synonymous[Leu229Leu]
884 .. 884 A/G rs150243147 + CDS Nonsynonymous[Tyr243Cys]
886 .. 886 T/C rs201334858 + CDS Nonsynonymous[Phe244Leu]
888 .. 888 C/T rs41303129 + CDS Synonymous[Phe244Phe]
904 .. 904 G/A rs143816043 + CDS Nonsynonymous[Ala250Thr]
906 .. 906 C/T rs36006006 + CDS Synonymous[Ala250Ala]
915 .. 915 C/T rs181558991 + CDS Synonymous[Ser253Ser]
917 .. 917 T/C rs55798516 + CDS Nonsynonymous[Ile254Thr]
948 .. 948 C/T rs55958233 + CDS Synonymous[Gly264Gly]
984 .. 984 C/T rs139570869 + CDS Synonymous[Gly276Gly]
1003 .. 1003 A/G rs180784380 + CDS Nonsynonymous[Ser283Gly]
1015 .. 1015 A/C rs146751657 + CDS Nonsynonymous[Asn287His]
1080 .. 1080 C/T rs17849927 + CDS Synonymous[Ile308Ile]
1083 .. 1083 C/T rs139133094 + CDS Synonymous[Asp309Asp]
1088 .. 1088 T/C rs199921339 + CDS Nonsynonymous[Leu311Pro]
1110 .. 1110 G/A rs149048093 + CDS Synonymous[Glu318Glu]
1141 .. 1141 C/T rs151292389 + CDS Nonsynonymous[Arg329Cys]
1146 .. 1146 G/A rs202227926 + CDS Synonymous[Lys330Lys]
1153 .. 1153 G/A rs147097934 + CDS Nonsynonymous[Asp333Asn]
1159 .. 1159 C/T rs200375779 + CDS Synonymous[Leu335Leu]
1181 .. 1181 A/G rs144147839 + CDS Nonsynonymous[Tyr342Cys]
1227 .. 1227 C/T rs138727410 + CDS Synonymous[Thr357Thr]
1273 .. 1273 A/G rs149364914 + CDS Nonsynonymous[Ser373Gly]
1285 .. 1285 C/T rs139900636 + CDS Nonsynonymous[Arg377Trp]
1291 .. 1291 G/A rs201134290 + CDS Nonsynonymous[Glu379Lys]
1304 .. 1304 A/G rs200800365 + CDS Nonsynonymous[Asn383Ser]
1317 .. 1317 G/A rs202132812 + CDS Synonymous[Leu387Leu]
1325 .. 1325 G/- rs34158214 + CDS
1335 .. 1335 C/T rs12593 - CDS Synonymous[Phe393Phe]
1374 .. 1374 C/A rs150918577 + CDS Nonsynonymous[Asn406Lys]
1428 .. 1428 G/A rs201337210 + CDS Synonymous[Thr424Thr]
1429 .. 1429 C/T rs149682899 + CDS Nonsynonymous[Arg425Trp]
1430 .. 1430 G/A rs200115323 + CDS Nonsynonymous[Arg425Gln]
1436 .. 1436 A/G rs119468008 + CDS Nonsynonymous[Tyr427Cys]
1451 .. 1451 C/G rs141260985 + CDS Nonsynonymous[Thr432Ser]
1462 .. 1462 A/G rs147730489 + CDS Nonsynonymous[Ile436Val]
1486 .. 1486 G/A rs200930703 + CDS Nonsynonymous[Asp444Asn]
1500 .. 1500 G/C rs201158713 + CDS Nonsynonymous[Glu448Asp]
1501 .. 1501 A/G rs200403220 + CDS Nonsynonymous[Thr449Ala]
1505 .. 1505 T/G rs199724504 + CDS Nonsynonymous[Val450Gly]
1507 .. 1507 C/T rs201331131 + CDS Nonsynonymous[Arg451Trp]
1512 .. 1512 G/A rs142600066 + CDS Synonymous[Ala452Ala]
1539 .. 1539 C/T rs141423403 + CDS Synonymous[Thr461Thr]
1540 .. 1540 G/A rs119468009 + CDS Nonsynonymous[Gly462Ser]
1546 .. 1546 G/A rs119468004 + CDS Nonsynonymous[Glu464Lys]
1560 .. 1560 G/A rs199874519 + CDS Nonsynonymous[Met468Ile]
1567 .. 1567 G/A rs142894121 + CDS Nonsynonymous[Ala471Thr]
1572 .. 1572 C/G rs200963031 + CDS Nonsynonymous[His472Gln]
1605 .. 1605 C/T rs139305619 + CDS Synonymous[Phe483Phe]
1611 .. 1611 T/C rs3738725 + CDS Synonymous[Ser485Ser]
1615 .. 1615 G/A rs202058665 + CDS Nonsynonymous[Glu487Lys]
1634 .. 1634 C/T rs199581236 + CDS Nonsynonymous[Thr493Ile]
1647 .. 1647 C/T rs201865243 + CDS Synonymous[Thr497Thr]
1650 .. 1650 G/C rs201171077 + CDS Nonsynonymous[Glu498Asp]
1652 .. 1652 A/G rs113308613 + CDS Nonsynonymous[Lys499Arg]
1660 .. 1660 A/C rs142051104 + CDS Nonsynonymous[Asn502His]
1671 .. 1671 C/T rs7545723 + CDS Synonymous[Pro505Pro]
1692 .. 1692 C/T rs139551241 + CDS Synonymous[Leu512Leu]
1695 .. 1695 C/G rs74589348 + CDS Synonymous[Val513Val]
1700 .. 1700 C/A/G rs61995958 + CDS
1711 .. 1711 A/C rs143650593 + CDS Nonsynonymous[Thr519Pro]
1716 .. 1716 C/T rs201618750 + CDS Synonymous[Tyr520Tyr]
1719 .. 1719 C/T rs141270350 + CDS Synonymous[Ser521Ser]
1761 .. 1761 G/A rs191944347 + CDS Synonymous[Lys535Lys]
1771 .. 1771 C/T rs141725964 + CDS Nonsynonymous[Arg539Cys]
1794 .. 1794 C/T rs150569155 + CDS Synonymous[Phe546Phe]
1795 .. 1795 G/A rs149335528 + CDS Nonsynonymous[Glu547Lys]
1809 .. 1809 C/T rs56043893 + CDS Synonymous[Ser551Ser]
1848 .. 1848 G/A rs200743857 + 3'UTR
1972 .. 1972 G/A rs149820067 + 3'UTR
2069 .. 2069 G/A rs117808661 + 3'UTR
2073 .. 2073 G/A rs188462608 + 3'UTR
2188 .. 2188 G/A rs113041399 + 3'UTR
2223 .. 2223 G/A rs113631619 + 3'UTR
2224 .. 2224 A/T rs112529851 + 3'UTR
2224 ^ 2225 -/T rs11420839 + 3'UTR
2228 ^ 2229 -/T rs199664948 + 3'UTR
2282 .. 2282 C/G rs12567953 + 3'UTR
2303 .. 2303 G/A rs8159 - 3'UTR
2348 .. 2348 G/A rs142056615 + 3'UTR
2482 .. 2482 G/A rs115542970 + 3'UTR
2495 .. 2495 G/A rs181352749 + 3'UTR
2520 .. 2520 G/A rs10482 - 3'UTR
2566 .. 2566 C/T rs16846762 + 3'UTR
2600 .. 2600 G/A rs145779574 + 3'UTR
2629 .. 2629 A/G rs12565212 + 3'UTR
2646 ^ 2647 -/T rs140711993 + 3'UTR
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene Repeat mask viewerRepeat Mask Viewer