H-InvDB_9.0 released on May 27, 2015.
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H-Inv ID (HIT)
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Definition*
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---
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H-Invitational ID:
HIT000023418
Accession number:
AK098588
Created date:
26-Mar-2013
Last modified:
27-May-2015
Definition:
DNA-(apurinic or apyrimidinic site) lyase; EC=3.1.-.-; EC=4.2.99.18; APEX nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1; Contains: DNA-(apurinic or apyrimidinic site) lyase, mitochondrial;
Select format
Flat file
XML file
Nucleotide sequence fasta
Protein sequence fasta
Transcript annotation summary
H-Inv ID
HIT000023418
H-Inv cluster ID
HIX0011489
H-Inv protein ID
HIP000084496
Accession number
AK098588.1
CAGE tag ID
NA
EST ID
NA
Genomic location
Chromosome
14
Location
14q11.2
Position
20923350- 20925925
Strand
+
Transcript feature
Representative transcript;
Splicing isoform
Coding potential
Protein coding;
Definition
DNA-(apurinic or apyrimidinic site) lyase; EC=3.1.-.-; EC=4.2.99.18; APEX nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1; Contains: DNA-(apurinic or apyrimidinic site) lyase, mitochondrial;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P27695
) [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene family / group
NA
Gene symbol/name
HGNC symbol
APEX1
HGNC aliases
"APEX nuclease (multifunctional DNA repair enzyme)"
HGNC name
APEX nuclease (multifunctional DNA repair enzyme) 1
DDBJ
NA
UniProt
APEX1
EC number
EC 3.1.-.-
Acting on Ester Bonds;
EC 4.2.99.18
DNA-(apurinic or apyrimidinic site) lyase;
KEGG metabolic pathway
NA
PubMed ID
1284593
;
1371347
;
1380454
;
1380694
;
1383925
;
1627644
;
1719477
;
1722334
;
8086453
;
8355688
;
8621488
;
8932375
;
9108029
;
9110174
;
9207062
;
9351835
;
9560228
;
9804799
;
10023679
;
10667800
;
11118054
;
11286553
;
11452037
;
11809897
;
11832948
;
12508121
;
12524539
;
14633989
;
15380100
;
15489334
;
15942031
;
16617147
;
17148573
;
17403694
;
18179823
;
18439621
;
18579163
;
18809583
;
19123919
;
19188445
;
19219073
;
19401441
;
19608861
;
19934257
;
20231292
;
20699270
;
21269460
;
21496894
;
21762700
;
ALL
;
Related H-InvDB links
Similarity Search Tool
Database links
RefSeq
NA
Ensembl
NA
Entrez Gene
Entrez Gene ID:328
;
KEGG GENES
KEGG GENES(328)
;
GeneCard
APEX1
;
*GeneCards is provided free to academic non-profit institutions.
etc
Human-Gene diversity Of Life-style related Diseases
;
Curation status
Human curated
Notes
NA