H-Inv ID |
HIT000050632 |
H-Inv cluster ID |
HIX0200897
|
H-Inv protein ID |
HIP000136930
|
Accession number |
BC015665.2
|
CAGE tag ID |
NA
|
EST ID |
NA
|
Genomic location
|
Chromosome |
6 |
Location |
6q25.1
|
Position |
150005542-
150039160
|
Strand |
-
|
Transcript feature
|
NO;
|
Coding potential
|
Protein coding;
|
Definition |
Similar to Serine/threonine-protein kinase LATS1; EC=2.7.11.1; Large tumor suppressor homolog 1; WARTS protein kinase; h-warts; |
Similarity category
|
Category: Similar to known protein(Category II).
|
Similar to known protein (O95835)
[Identity/coverage = 100.0%/20.18%] to
Homo sapiens (Human). protein.
|
Gene family / group |
NA
|
Gene symbol/name |
HGNC symbol |
LATS1
|
HGNC aliases |
"LATS (large tumor suppressor, Drosophila) homolog 1", "LATS, large tumor suppressor, homolog 1 (Drosophila)"
|
HGNC name |
large tumor suppressor kinase 1
|
DDBJ |
LATS1
|
UniProt |
LATS1
|
EC number |
EC 2.7.11.1non-specific serine/threonine protein kinase;
|
KEGG metabolic pathway |
04150
:mTOR signaling pathway;
04210
:Apoptosis;
04310
:Wnt signaling pathway;
04320
:Dorso-ventral axis formation;
04340
:Hedgehog signaling pathway;
04350
:TGF-beta signaling pathway;
04360
:Axon guidance;
04370
:VEGF signaling pathway;
04510
:Focal adhesion;
04520
:Adherens junction;
04530
:Tight junction;
04540
:Gap junction;
04620
:Toll-like receptor signaling pathway;
04630
:Jak-STAT signaling pathway;
04660
:T cell receptor signaling pathway;
04662
:B cell receptor signaling pathway;
04664
:Fc epsilon RI signaling pathway;
04720
:Long-term potentiation;
04730
:Long-term depression;
04810
:Regulation of actin cytoskeleton;
04910
:Insulin signaling pathway;
04912
:GnRH signaling pathway;
04920
:Adipocytokine signaling pathway;
05010
:Alzheimer's disease;
05210
:Colorectal cancer;
|
PubMed ID |
9988268;
10518011;
10831611;
15122335;
15144186;
15220930;
15489334;
15688006;
17344846;
17525332;
18158288;
18669648;
18691976;
19369195;
19690332;
19739119;
19927127;
20303269;
ALL;
|
Related H-InvDB links |
Similarity Search Tool
|
Database links |
RefSeq |
NA
|
Ensembl |
NA
|
Entrez Gene |
Entrez Gene ID:9113;
|
KEGG GENES |
KEGG GENES(9113);
|
GeneCard |
LATS1;
*GeneCards is provided free to academic non-profit institutions.
|
etc |
Human-Gene diversity Of Life-style related Diseases;
|
Curation status |
Auto-annotated
|
Notes |
NA
|