H-InvDB x AHG DB
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H-InvDB_9.0 released on May 27, 2015.
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H-Invitational ID: HIT000053157 Accession number: BC047523 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Calmodulin; CaM;
 
 

Transcript original information
Accession number BC047523.1
CAGE tag ID NA
EST ID NA
Clone Number IMAGE:4819353
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ;
Sequence data provider Provider:MGC/NCI; 
Annotation project H-Invitational FLcDNA
Length of cDNA 3718[bp] (No. of exon:7)[A:965 T:1119 G:877 C:757]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type Brain, hippocampus
Develpmental stage NA
Mini-G
Sequence quality information
CDS feature Complete CDS
Kozak sequence NA
PolyA Site: 3703(+) Signal: 3685-3689(+)
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) NA
Transcript quality feature NMD predicted; 
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0011883
Genomic location  G-integra Help Chromosome 14
Location 14q32.11
Position 90863377- 90874396
Strand +
Possible duplicated location(s) NA
Gene structure 7 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:801; 
KEGG GENES KEGG GENES(801); 
GeneCard NA *GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS;  G-integraG-integra;  cDNA-genome alignmentcDNA-genome alignment; 

Predicted CDS information
HIP ID HIP000024994
Predicted CDS 203..652;  149[aa];  Orientation:+2; 
Codon Adaptation Index (CAI). 0.745
Database links RefSeq NP_001734;  NP_005175;  NP_008819; 
UniProt P62144;  P62149;  P62151;  P62155;  P62156;  P62157;  P62158;  P62160;  P62161;  P62204;  Q5EHV7;  Q5RAD2;  Q6IT78;  Q6PI52;  Q6YNX6;  Q71UH6; 
CCDS CCDS1832;  CCDS33061;  CCDS9892; 

Motif information
ORF

length(149),orf(203:652) MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQ DMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK* 		a.a.
length		 InterPro Name
length(66), motif(3:68) 66 IPR011992 EF-hand domain pair [Domain]
length(36), motif(8:43) 36 IPR002048 EF-hand domain [Domain]
length(29), motif(12:40) 29 IPR002048 EF-hand domain [Domain]
length(60), motif(14:73) 60 IPR011992 EF-hand domain pair [Domain]
length(13), motif(21:33) 13 IPR018247 EF-Hand 1, calcium-binding site [Binding_site]
length(36), motif(44:79) 36 IPR002048 EF-hand domain [Domain]
length(29), motif(48:76) 29 IPR002048 EF-hand domain [Domain]
length(13), motif(57:69) 13 IPR018247 EF-Hand 1, calcium-binding site [Binding_site]
length(79), motif(69:147) 79 IPR011992 EF-hand domain pair [Domain]
length(36), motif(81:116) 36 IPR002048 EF-hand domain [Domain]
length(29), motif(85:113) 29 IPR002048 EF-hand domain [Domain]
length(61), motif(86:146) 61 IPR011992 EF-hand domain pair [Domain]
length(13), motif(94:106) 13 IPR018247 EF-Hand 1, calcium-binding site [Binding_site]
length(33), motif(117:149) 33 IPR002048 EF-hand domain [Domain]
length(29), motif(121:149) 29 IPR002048 EF-hand domain [Domain]
length(13), motif(130:142) 13 IPR018247 EF-Hand 1, calcium-binding site [Binding_site]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000053157
H-Inv cluster ID Locus viewHIX0011883
Accession number BC047523.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help Representative H-Inv IDRepresentative transcript;  Splicing isoformSplicing isoform
Coding potential  Help Protein coding; 
Definition Calmodulin; CaM;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (P62158)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Experimental evidence Protein evidence
PubMed ID 1474585;  2223880;  2445749;  3182832;  6385987;  7093203;  7803388;  7925473;  9681195;  9804419;  9927666;  11685248;  11807546;  12485993;  12508121;  12577052;  12871148;  15489334;  15592455;  15719022;  15746192;  15815621;  16127172;  16299511;  16760425;  17719545;  18650434;  18669648;  19608861;  19690332;  20466722;  21167176;  21269460;  21406692;  22484487;  23040497;  ALL; 
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol NA
HGNC aliases NA
HGNC name NA
DDBJ NA
UniProt CALM3
EC number NA
GGDB
(GlycoGene Database)
 Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000024994
No. of interaction 151
Interaction partner(s) HIP000021606;  HIP000021999;  HIP000022920;  HIP000023827;  HIP000024080;  HIP000024373;  HIP000024429;  HIP000024433;  HIP000024603;  HIP000024723;  HIP000025001;  HIP000025001;  HIP000025184;  HIP000025256;  HIP000025619;  HIP000025619;  HIP000025817;  HIP000026231;  HIP000026561;  HIP000026650;  HIP000027004;  HIP000028648;  HIP000028806;  HIP000028948;  HIP000029106;  HIP000029669;  HIP000029733;  HIP000029919;  HIP000030386;  HIP000030765;  HIP000032098;  HIP000032397;  HIP000032749;  HIP000032846;  HIP000032870;  HIP000033674;  HIP000034651;  HIP000036736;  HIP000036736;  HIP000037607;  HIP000039461;  HIP000040522;  HIP000040680;  HIP000041107;  HIP000041308;  HIP000041429;  HIP000042652;  HIP000044043;  HIP000046719;  HIP000046896;  HIP000047664;  HIP000048107;  HIP000048801;  HIP000049174;  HIP000049915;  HIP000049997;  HIP000050005;  HIP000051355;  HIP000052086;  HIP000052329;  HIP000052586;  HIP000053726;  HIP000054580;  HIP000057472;  HIP000057536;  HIP000058633;  HIP000059613;  HIP000060603;  HIP000060858;  HIP000063272;  HIP000063383;  HIP000064456;  HIP000065273;  HIP000065299;  HIP000067584;  HIP000067617;  HIP000069367;  HIP000069837;  HIP000069887;  HIP000071741;  HIP000072281;  HIP000074095;  HIP000074116;  HIP000074361;  HIP000075478;  HIP000075551;  HIP000075910;  HIP000076060;  HIP000077638;  HIP000079704;  HIP000080465;  HIP000080779;  HIP000082634;  HIP000082747;  HIP000083424;  HIP000084122;  HIP000084148;  HIP000085076;  HIP000085708;  HIP000086514;  HIP000086839;  HIP000086928;  HIP000088283;  HIP000088399;  HIP000091330;  HIP000091500;  HIP000093491;  HIP000094907;  HIP000095322;  HIP000096838;  HIP000096868;  HIP000097117;  HIP000097471;  HIP000098226;  HIP000099275;  HIP000101550;  HIP000101991;  HIP000101991;  HIP000102217;  HIP000102293;  HIP000102581;  HIP000102898;  HIP000104180;  HIP000104327;  HIP000104847;  HIP000105099;  HIP000106041;  HIP000106185;  HIP000107233;  HIP000107622;  HIP000109499;  HIP000110634;  HIP000113005;  HIP000113507;  HIP000116213;  HIP000116715;  HIP000117036;  HIP000128485;  HIP000129551;  HIP000131477;  HIP000136079;  HIP000145170;  HIP000146754;  HIP000148595;  HIP000176829;  HIP000177086;  HIP000200174;  HIP000246810;  HIP000254467;  HIP000254467;  HIP000359409; 
BIND 19092;  200006;  200007;  200008;  200009;  200010;  200012;  200013;  300817;  301726;  58062; 
DIP 102879E;  103745E;  104171E;  112446E;  112851E;  113176E;  114308E;  114414E;  114783E;  114827E;  115144E;  115983E;  116983E;  117513E;  175832E;  177437E;  185610E;  31E;  489E; 
MINT MINT-15764;  MINT-15765;  MINT-15766;  MINT-16955;  MINT-16956;  MINT-16957;  MINT-17793;  MINT-17795;  MINT-3295975;  MINT-48052;  MINT-48084;  MINT-48113;  MINT-48186;  MINT-48261;  MINT-48323;  MINT-48456;  MINT-48550;  MINT-48603;  MINT-48670;  MINT-48738;  MINT-48841;  MINT-48939;  MINT-49007;  MINT-49067;  MINT-49123;  MINT-49173;  MINT-49204;  MINT-49236;  MINT-49274;  MINT-49341;  MINT-49428;  MINT-49484;  MINT-49550;  MINT-49596;  MINT-5114545;  MINT-5114562;  MINT-51633;  MINT-51634;  MINT-51635;  MINT-51636;  MINT-51637;  MINT-51638;  MINT-51639;  MINT-51640;  MINT-51641;  MINT-51642;  MINT-58231;  MINT-58232;  MINT-58233;  MINT-58242;  MINT-58244;  MINT-6175484;  MINT-63955;  MINT-63956;  MINT-6595938;  MINT-6596013;  MINT-67316;  MINT-7148437;  MINT-7297878;  MINT-7899812;  MINT-7988100;  MINT-7988123;  MINT-8200174;  MINT-8200205; 
HPRD 00017;  00019;  00032;  00043;  00045;  00051;  00146;  00239;  00251;  00277;  00279;  00352;  00455;  00559;  00579;  00589;  00592;  00656;  00677;  00679;  00777;  00800;  00828;  00918;  00941;  00942;  00975;  01028;  01038;  01061;  01098;  01142;  01166;  01167;  01168;  01169;  01198;  01203;  01224;  01227;  01235;  01238;  01239;  01241;  01281;  01286;  01346;  01347;  01387;  01404;  01422;  01442;  01476;  01491;  01498;  01535;  01536;  01540;  01549;  01550;  01585;  01615;  01618;  01628;  01684;  01710;  01787;  01790;  01817;  01818;  01843;  01852;  01855;  01861;  01862;  01863;  01890;  02043;  02177;  02274;  02367;  02429;  02437;  02484;  02524;  02543;  02577;  02795;  02811;  02884;  02917;  02963;  02985;  03007;  03009;  03015;  03070;  03072;  03183;  03195;  03276;  03283;  03311;  03378;  03390;  03428;  03465;  03533;  03538;  03648;  03677;  03757;  03771;  03780;  03828;  03833;  03914;  03929;  03947;  03965;  04009;  04043;  04045;  04130;  04172;  04235;  04274;  04300;  04462;  04541;  04585;  04713;  04728;  04921;  04978;  04979;  04980;  05059;  05125;  05230;  05255;  05270;  05322;  05327;  05353;  05412;  05442;  05457;  05667;  05803;  05804;  05890;  05934;  05982;  06060;  06120;  06467;  06532;  06692;  06763;  06886;  07505;  07519;  08014;  08356;  08555;  08599;  08830;  08922;  08946;  09073;  09077;  09235;  09253;  09315;  09323;  10040;  10369;  10406;  10515;  10551;  10848;  11049;  11366;  11474;  11476;  11613;  11792;  11871;  13000;  13882;  14727;  14746;  15253;  15302;  15926;  15999;  16241;  17279;  17627;  18124;  18125;  18206;  19599; 
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:801; 
KEGG GENES KEGG GENES(801); 
GeneCard NA *GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases; 
Curation status Human curated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool;  TACTTACT; 
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
FR ID FR049310
Accession
Description
Location
PMID

Gene ontology information
Molecular function calcium ion binding (GO:0005509); 

Subcellular localization information  Last modified:27-May-2015
WoLF PSORT cytosol;  nuclear;  plasma membrane;  Other; 
Target P Other
SOSUI soluble protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified:27-May-2015
Start End PDB_ID E-value Identity Coverage SCOP_ID
4 147 1a29A 1e-31 100.0 144/144 a.39.1.5
Related H-InvDB links GTOP GTOP

Gene expression information  H-ANGEL DNAProbeLocator Last modified:27-May-2015
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator		 AceGene NA
Affymetrix
GeneChip		 HG-Focus 200655_s_at; 
HG-U133 200653_s_at;  200655_s_at;  209563_x_at;  213688_at; 
HG-U133A 200653_s_at;  200655_s_at;  209563_x_at;  213688_at; 
HG-U133A_2 200653_s_at;  200655_s_at;  209563_x_at;  213688_at; 
HG-U133B NA
HG-U133_Plus_2 200653_s_at;  200655_s_at;  209563_x_at;  213688_at; 
HG-U95 41143_at;  955_at; 
HG-U95A 41143_at; 
HG-U95B NA
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 3051591;  3548351;  3548352;  3548360;  3548362;  3548363;  3548366;  3548368;  3548371;  3548372;  3548374;  3548375;  3576080;  3576081;  3576083;  3576084;  3576085;  3983844;  3983845; 
HuGeneFL NA
Agilent Human 1A Oligo Microarray:PGID215 A_23_P163179; 
Whole Human Genome Oligo Microarray:PGID247 A_23_P163178; 
Related H-InvDB links H-ANGELH-ANGEL;  DNAProbeLocatorDNAProbeLocator; 

Evolutionary information  Evola Help Last modified:27-May-2015
Relationship Species Accession number MGI Links
Orthology Macaca sp. (Macaque) AB220420 G-integraG-integra
Orthology Rattus sp. (Rat) AF178845 G-integraG-integra
Orthology Danio sp. (Zebrafish) BC053150 G-integraG-integra
Orthology Mus sp. (Mouse) BC054805 MGI:88251 G-integraG-integra
Orthology Bos sp. (Cow) BC123890 G-integraG-integra
Orthology Pongo sp. (Orangutan) CR859086 G-integraG-integra
Orthology Gallus sp. (Chicken) ENSGALT00000037622 G-integraG-integra
Orthology Oryzias sp. (Medaka) ENSORLT00000022188 G-integraG-integra
Orthology Pan sp. (Chimpanzee) ENSPTRT00000047828 G-integraG-integra
Orthology Tetraodon sp. (Tetraodon) GSTENT00018439001 G-integraG-integra
Orthology Takifugu sp. (Fugu) SINFRUT00000130883 G-integraG-integra
Orthology Monodelphis sp. (Opossum) XM_001371471 G-integraG-integra
Orthology Equus sp. (Horse) XM_001494208 G-integraG-integra
Orthology Canis sp. (Dog) XM_537537 G-integraG-integra
Phylogenetic tree [View by ATV]
 Neighbor-joining (phb) 
Related H-InvDB links EvolaEvola;  dN/dS (under constraction); 

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
30 .. 30 C/T rs188359112 + 5'UTR
35 .. 35 C/T rs146545930 + 5'UTR
39 .. 39 A/T rs181001910 + 5'UTR
42 .. 42 C/T rs141007341 + 5'UTR
51 .. 51 G/T rs12886186 + 5'UTR
117 .. 117 A/G rs12886342 + 5'UTR
171 .. 171 C/T rs12886083 + 5'UTR
271 .. 271 T/C rs144339242 + CDS Synonymous[Asp23Asp]
274 .. 274 C/T rs267607278 + CDS Synonymous[Gly24Gly]
321 .. 321 T/C rs199950662 + CDS Nonsynonymous[Leu40Pro]
327 .. 327 A/T rs199897752 + CDS Nonsynonymous[Gln42Leu]
351 .. 351 A/G rs202194260 + CDS Nonsynonymous[Gln50Arg]
363 .. 363 A/T rs267607276 + CDS Nonsynonymous[Asn54Ile]
445 .. 445 T/C rs200250055 + CDS Synonymous[Asp81Asp]
474 .. 474 G/A rs11541171 + CDS Nonsynonymous[Arg91Gln]
495 .. 495 A/G rs267607277 + CDS Nonsynonymous[Asn98Ser]
505 .. 505 C/T rs143503733 + CDS Synonymous[Ile101Ile]
526 .. 526 C/T rs139706811 + CDS Synonymous[His108His]
604 .. 604 C/T rs193072150 + CDS Synonymous[Asp134Asp]
628 .. 628 C/T rs199744595 + CDS Synonymous[Phe142Phe]
663 .. 663 T/G rs201339726 + 3'UTR
670 .. 670 C/T rs200742588 + 3'UTR
786 .. 786 T/C rs5871 + 3'UTR
890 .. 890 C/T rs112958092 + 3'UTR
990 .. 990 G/A rs187714594 + 3'UTR
1105 .. 1105 C/T rs1059285 + 3'UTR
1143 ^ 1144 -/GG rs139060064 + 3'UTR
1148 .. 1148 A/G rs199697317 - 3'UTR
1221 ^ 1222 -/T rs35149335 + 3'UTR
1224 .. 1224 T/- rs71771679 + 3'UTR
1224 ^ 1225 -/T rs71823341 + 3'UTR
1238 ^ 1239 -/T rs199855088 + 3'UTR
1238 ^ 1239 -/T/TTT rs56856377 + 3'UTR
1239 .. 1239 C/G/T rs111860684 + 3'UTR
1407 .. 1407 G/T rs11541170 - 3'UTR
1408 .. 1408 C/T rs116646015 + 3'UTR
1452 .. 1452 A/G rs1059296 + 3'UTR
1542 .. 1542 G/A rs61989066 + 3'UTR
1544 .. 1544 A/G rs77928599 + 3'UTR
1553 .. 1553 A/C/T rs77916091 + 3'UTR
1556 .. 1556 C/A rs78459823 + 3'UTR
1566 .. 1566 C/A rs146008731 + 3'UTR
1651 .. 1651 A/G rs115723958 + 3'UTR
1673 .. 1673 T/A rs138659409 + 3'UTR
1719 .. 1719 C/A rs75951656 + 3'UTR
1739 .. 1739 C/T rs192521929 + 3'UTR
1759 .. 1759 G/A rs183678923 + 3'UTR
1789 .. 1789 T/G rs3814846 - 3'UTR
1796 .. 1796 C/T rs61989067 + 3'UTR
1798 .. 1798 T/- rs71461907 + 3'UTR
1798 ^ 1799 -/C rs200711428 + 3'UTR
1799 .. 1799 T/C rs75202062 + 3'UTR
1813 .. 1813 C/G rs3814845 - 3'UTR
2050 .. 2050 A/G rs141870617 + 3'UTR
2066 .. 2066 G/A rs3814844 - 3'UTR
2210 .. 2210 C/T rs186848664 + 3'UTR
2238 .. 2238 C/T rs35418035 + 3'UTR
2320 .. 2320 T/G rs3814843 - 3'UTR
2332 .. 2332 C/A rs139692985 + 3'UTR
2384 .. 2384 G/A rs192452102 + 3'UTR
2453 .. 2453 A/G rs184803743 + 3'UTR
2494 .. 2494 T/C rs149760583 + 3'UTR
2571 .. 2571 A/G rs189778902 + 3'UTR
2579 .. 2579 T/C rs181805019 + 3'UTR
2586 .. 2586 G/T rs184371119 + 3'UTR
2618 .. 2618 T/G rs189147924 + 3'UTR
2619 .. 2619 T/C rs181955035 + 3'UTR
2719 .. 2719 G/C rs3179089 + 3'UTR
3021 .. 3021 C/T rs184950622 + 3'UTR
3080 .. 3080 C/A rs11539544 + 3'UTR
3105 .. 3105 C/T rs1058903 + 3'UTR
3315 .. 3315 C/G rs140025082 + 3'UTR
3348 .. 3348 C/T rs115172487 + 3'UTR
3456 .. 3456 A/G rs145426711 + 3'UTR
3586 .. 3586 G/A rs147728175 + 3'UTR
3645 .. 3645 G/C rs142500788 + 3'UTR
3651 .. 3651 T/C rs144946670 + 3'UTR
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD); 
Related H-InvDB links VaryGeneVaryGene;  Repeat mask viewerRepeat Mask Viewer;