H-InvDB x AHG DB
Transcript view
H-InvDB_9.0 released on May 27, 2015.
Search by for Advanced Search
Home Quick guide Navi BLAST Site map Download Contact us Help
H-Invitational ID: HIT000074138 Accession number: AF216311 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Sperm acrosome membrane-associated protein 3; Cancer/testis antigen 54; CT54; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17; Lysozyme-like protein 3; Sperm lysozyme-like protein 1; Sperm protein reactive with antisperm antibodies; Sperm protein reactive with ASA; Contains: Sperm acrosome membrane-associated protein 3, membrane form; Contains: Sperm acrosome membrane-associated protein 3, processed form;
 
 

Transcript original information
Accession number AF216311.1
CAGE tag ID NA
EST ID NA
Clone Number NA
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ; Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (SPACA3) ; Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (SPACA3);
Sequence data provider NA
Annotation project NA
Length of cDNA 820[bp] (No. of exon:5)[A:168 T:185 G:253 C:214]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type testis
Develpmental stage NA
Mini-G
Sequence quality information
CDS feature Complete CDS
Kozak sequence NA
PolyA NA
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) NA
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0039076
Genomic location  G-integra Help Chromosome 17
Location 17q11.2
Position 31318882- 31324892
Strand +
Possible duplicated location(s) NA
Gene structure 5 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:124912
KEGG GENES KEGG GENES(124912)
GeneCard GeneCardSPACA3*GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000113228
Predicted CDS 76..723;  215[aa];  Orientation:+1; 
Codon Adaptation Index (CAI). 0.794
Database links RefSeq NP_776246
UniProt Q8IXA5
CCDS CCDS11275

Motif information
ORF

length(215),orf(76:723)
MVSALRGAPLIRVHSSPVSSPSVSGPRRLVSCLSSQSSALSQSGGGSTSA
AGIEARSRALRRRWCPAGIMLLALVCLLSCLLPSSEAKLYGRCELARVLH
DFGLDGYRGYSLADWVCLAYFTSGFNAAALDYEADGSTNNGIFQINSRRW
CSNLTPNVPNVCRMYCSDLLNPNLKDTVICAMKITQEPQGLGYWEAWRHH
CQGKDLTEWVDGCDF*
a.a.
length
InterPro Name
length(127), motif(88:214) 127 IPR023346 Lysozyme-like domain [Domain]
length(128), motif(88:215) 128 IPR001916 Glycoside hydrolase, family 22 [Family]
length(127), motif(88:214) 127 IPR001916 Glycoside hydrolase, family 22 [Family]
length(125), motif(89:213) 125 IPR001916 Glycoside hydrolase, family 22 [Family]
length(19), motif(89:107) 19 IPR000974 Glycoside hydrolase, family 22, lysozyme [Family]
length(11), motif(90:100) 11 IPR001916 Glycoside hydrolase, family 22 [Family]
length(10), motif(110:119) 10 IPR001916 Glycoside hydrolase, family 22 [Family]
length(13), motif(120:132) 13 IPR000974 Glycoside hydrolase, family 22, lysozyme [Family]
length(17), motif(137:153) 17 IPR001916 Glycoside hydrolase, family 22 [Family]
length(11), motif(156:166) 11 IPR000974 Glycoside hydrolase, family 22, lysozyme [Family]
length(10), motif(160:169) 10 IPR001916 Glycoside hydrolase, family 22 [Family]
length(19), motif(162:180) 19 IPR019799 Glycoside hydrolase, family 22, conserved site [Conserved_site]
length(16), motif(167:182) 16 IPR000974 Glycoside hydrolase, family 22, lysozyme [Family]
length(16), motif(170:185) 16 IPR001916 Glycoside hydrolase, family 22 [Family]
length(10), motif(189:198) 10 IPR000974 Glycoside hydrolase, family 22, lysozyme [Family]
length(12), motif(190:201) 12 IPR001916 Glycoside hydrolase, family 22 [Family]
length(14), motif(199:212) 14 IPR000974 Glycoside hydrolase, family 22, lysozyme [Family]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000074138
H-Inv cluster ID Locus viewHIX0039076
Accession number AF216311.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help Representative H-Inv IDRepresentative transcript;  Splicing isoformSplicing isoform
Coding potential  Help Protein coding; 
Definition Sperm acrosome membrane-associated protein 3; Cancer/testis antigen 54; CT54; Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17; Lysozyme-like protein 3; Sperm lysozyme-like protein 1; Sperm protein reactive with antisperm antibodies; Sperm protein reactive with ASA; Contains: Sperm acrosome membrane-associated protein 3, membrane form; Contains: Sperm acrosome membrane-associated protein 3, processed form;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (Q8IXA5)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Experimental evidence Protein evidence
PubMed ID 1260649312975309147471611548933416014814ALL
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol SPACA3
HGNC aliases NA
HGNC name sperm acrosome associated 3
DDBJ NA
UniProt SPACA3
EC number NA
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000113228
No. of interaction 1
Interaction partner(s) HIP000161463
BIND NA
DIP NA
MINT NA
HPRD 00072; 
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:124912
KEGG GENES KEGG GENES(124912)
GeneCard GeneCardSPACA3*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Human curated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
NA

Gene ontology information
Molecular function lysozyme activity (GO:0003796); 

Subcellular localization information  Last modified:27-May-2015
WoLF PSORT extracellular;  mitochondria; 
Target P mitochondria
SOSUI membrane protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified:27-May-2015
Start End PDB_ID E-value Identity Coverage SCOP_ID
89 214 132lA 8e-36 38.1 126/129 d.2.1.2
Related H-InvDB links GTOP GTOP

Gene expression information  H-ANGEL DNAProbeLocator Last modified:27-May-2015
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator
AceGene NA
Affymetrix
GeneChip
HG-Focus NA
HG-U133 243621_at; 
HG-U133A NA
HG-U133A_2 NA
HG-U133B 243621_at; 
HG-U133_Plus_2 243621_at; 
HG-U95 83188_at; 
HG-U95A NA
HG-U95B NA
HG-U95C NA
HG-U95D 83188_at; 
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 3717904;  3717905;  3717908;  3717909;  3717910;  3717911;  3717912;  3717913;  3717914;  3717915; 
HuGeneFL NA
Agilent Human 1A Oligo Microarray:PGID215 A_23_P317244;  A_23_P38434; 
Whole Human Genome Oligo Microarray:PGID247 A_23_P317244; 
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Evolutionary information  Evola Help Last modified:27-May-2015
Relationship Species Accession number MGI Links
Orthology Danio sp. (Zebrafish) BC092921 G-integraG-integra
Orthology Mus sp. (Mouse) BC100503 G-integraG-integra
Orthology Bos sp. (Cow) ENSBTAT00000000449 G-integraG-integra
Orthology Equus sp. (Horse) ENSECAT00000006280 G-integraG-integra
Orthology Macaca sp. (Macaque) ENSMMUT00000015978 G-integraG-integra
Orthology Pongo sp. (Orangutan) ENSPPYT00000010345 G-integraG-integra
Orthology Canis sp. (Dog) FJ396442 G-integraG-integra
Orthology Rattus sp. (Rat) XM_001080990 G-integraG-integra
Orthology Monodelphis sp. (Opossum) XM_001364024 G-integraG-integra
Phylogenetic tree [View by ATV]
Neighbor-joining (phb) 
Related H-InvDB links EvolaEvoladN/dS (under constraction); 

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
52 ^ 53 -/CTG rs34817428 + 5'UTR
53 ^ 54 -/CTG rs146956319 + 5'UTR
54 ^ 55 -/GCT rs5820010 + 5'UTR
55 ^ 56 -/GCT rs34426239 + 5'UTR
65 ^ 66 -/TGC rs3052914 + 5'UTR
81 .. 81 C/T rs12325917 + CDS Synonymous[Val2Val]
91 .. 91 C/T rs200193792 + CDS Nonsynonymous[Arg6Trp]
110 .. 110 G/A rs34727343 - CDS Nonsynonymous[Arg12Lys]
188 .. 188 C/T rs201878199 + CDS Nonsynonymous[Ser38Leu]
205 .. 205 G/T rs200979098 + CDS Nonsynonymous[Gly44Cys]
228 .. 228 C/T rs139396445 + CDS Synonymous[Ala51Ala]
269 .. 269 G/A rs202186032 + CDS Nonsynonymous[Cys65Tyr]
294 .. 294 C/T rs142631993 + CDS Synonymous[Ala73Ala]
314 .. 314 G/A rs16967845 + CDS Nonsynonymous[Cys80Tyr]
334 .. 334 G/A rs201128410 + CDS Nonsynonymous[Ala87Thr]
335 .. 335 C/T rs201437710 + CDS Nonsynonymous[Ala87Val]
359 .. 359 T/C rs201729342 + CDS Nonsynonymous[Leu95Pro]
374 .. 374 A/G rs28963 - CDS Nonsynonymous[His100Arg]
382 .. 382 G/A rs200269504 + CDS Nonsynonymous[Gly103Arg]
390 .. 390 C/T rs199736765 + CDS Synonymous[Asp105Asp]
392 .. 392 G/C rs149695417 + CDS Nonsynonymous[Gly106Ala]
416 .. 416 A/G rs145497386 + CDS Nonsynonymous[Asp114Gly]
444 .. 444 C/T rs200596990 + CDS Synonymous[Ser123Ser]
457 .. 457 G/A rs35420663 - CDS Nonsynonymous[Ala128Thr]
465 ^ 466 -/G rs11369381 + CDS
471 .. 471 C/T rs146926616 + CDS Synonymous[Tyr132Tyr]
517 .. 517 C/T rs147752062 + CDS Nonsynonymous[Arg148Trp]
520 .. 520 A/T rs142634426 + CDS Nonsynonymous[Arg149Trp]
542 .. 542 C/T rs143361724 + CDS Nonsynonymous[Pro156Leu]
546 .. 546 C/T rs16967849 + CDS Synonymous[Asn157Asn]
554 .. 554 A/G rs201467254 + CDS Nonsynonymous[Asn160Ser]
563 .. 563 G/A rs141497752 + CDS Nonsynonymous[Arg163Gln]
605 .. 605 C/A rs138285109 + CDS Nonsynonymous[Thr177Asn]
619 .. 619 A/G rs62068261 + CDS Nonsynonymous[Met182Val]
630 .. 630 C/A rs146053986 + CDS Synonymous[Thr185Thr]
638 .. 638 C/T rs35014584 - CDS Nonsynonymous[Pro188Leu]
644 .. 644 G/T rs149534103 + CDS Nonsynonymous[Gly190Val]
687 .. 687 A/T rs139783886 + CDS Nonsynonymous[Lys204Asn]
703 .. 703 G/A rs201825625 + CDS Nonsynonymous[Val210Met]
708 .. 708 T/C rs28956 - CDS Synonymous[Asp211Asp]
709 .. 709 G/A rs142148066 + CDS Nonsynonymous[Gly212Ser]
730 .. 730 C/T rs200160944 + 3'UTR
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene;  Repeat mask viewerRepeat Mask Viewer