H-InvDB x AHG DB
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H-InvDB_9.0 released on May 27, 2015.
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H-Invitational ID: HIT000087143 Accession number: BC008709 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Similar to Beta-adducin; Erythrocyte adducin subunit beta;
 
 

Transcript original information
Accession number BC008709.1
CAGE tag ID NA
EST ID NA
Clone Number IMAGE:3342912
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ; Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (ADD2) ; Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (ADD2);
Sequence data provider NA
Annotation project NA
Length of cDNA 2160[bp] (No. of exon:6)[A:603 T:467 G:521 C:569]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type Eye, retinoblastoma
Develpmental stage NA
Mini-G
Sequence quality information
CDS feature N-truncated
Kozak sequence NA
PolyA Site: 2142(+)
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) CAGGAG;  TAGAAG; 
Transcript quality feature Truncation; 
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0029808
Genomic location  G-integra Help Chromosome 2
Location 2p13.3
Position 70889264- 70905886
Strand -
Possible duplicated location(s) NA
Gene structure 6 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:119
KEGG GENES KEGG GENES(119)
GeneCard GeneCardADD2*GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000131031
Predicted CDS 1..849;  282[aa];  Orientation:+1; 
Codon Adaptation Index (CAI). 0.8

Motif information
ORF

length(282),orf(1:849)
VADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQE
VLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDED
TKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPA
KSAPASPVQSPAKEAETKSPLVSPSKSLEEGTKKTETSKAATTEPETTQP
EGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSP
EGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES*
a.a.
length
InterPro Name
length(282), motif(1:282) 282 IPR027773 Beta-adducin [Family]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000087143
H-Inv cluster ID Locus viewHIX0029808
Accession number BC008709.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help NO; 
Coding potential  Help Protein coding; 
Definition Similar to Beta-adducin; Erythrocyte adducin subunit beta;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (P35612)  [Identity/coverage = 100.0%/38.84%] to Homo sapiens (Human). protein.
Experimental evidence Protein evidence
PubMed ID 184060385667988810272129510581470203915489334158156212140669221697133ALL
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol ADD2
HGNC aliases NA
HGNC name adducin 2 (beta)
DDBJ NA
UniProt ADD2
EC number NA
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000131031
No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:119
KEGG GENES KEGG GENES(119)
GeneCard GeneCardADD2*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Auto-annotated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool;  TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
FR ID FR181793
Accession
Description
Location
PMID

Gene ontology information
Cellular component cytoskeleton (GO:0005856); 

Subcellular localization information  Last modified:27-May-2015
WoLF PSORT nuclear;  cytosol; 
Target P Other
SOSUI soluble protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Gene expression information  H-ANGEL DNAProbeLocator Last modified:27-May-2015
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator
AceGene NA
Affymetrix
GeneChip
HG-Focus NA
HG-U133 205268_s_at; 
HG-U133A 205268_s_at; 
HG-U133A_2 205268_s_at; 
HG-U133B NA
HG-U133_Plus_2 205268_s_at; 
HG-U95 36051_s_at;  36052_at; 
HG-U95A 36051_s_at;  36052_at; 
HG-U95B NA
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 2558755;  2558756;  2558765;  2558767;  2558768;  2558772;  2558774; 
HuGeneFL S81083_cds1_at;  X58199_s_at; 
Agilent Human 1A Oligo Microarray:PGID215 A_23_P209856; 
Whole Human Genome Oligo Microarray:PGID247 A_23_P209856;  A_23_P421436; 
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
44 .. 44 A/G rs201449367 - CDS Nonsynonymous[Lys15Arg]
66 .. 66 C/T rs188058882 - CDS Synonymous[Asp22Asp]
96 .. 96 G/A rs34884423 + CDS Synonymous[Pro32Pro]
101 .. 101 G/A rs150426440 - CDS Nonsynonymous[Arg34His]
105 .. 105 C/T rs199802003 - CDS Synonymous[Ile35Ile]
170 .. 170 A/G rs112879637 - CDS Nonsynonymous[Lys57Arg]
177 .. 177 A/C rs145174076 - CDS Synonymous[Arg59Arg]
207 .. 207 G/C rs115841739 - CDS Synonymous[Ala69Ala]
234 .. 234 C/T rs148402316 - CDS Synonymous[Ser78Ser]
243 .. 243 C/G rs201133279 - CDS Synonymous[Ala81Ala]
251 .. 251 G/C rs149689098 - CDS Nonsynonymous[Ser84Thr]
254 .. 254 G/T rs114311724 - CDS Nonsynonymous[Arg85Leu]
295 .. 295 G/A rs139586218 - CDS Nonsynonymous[Glu99Lys]
323 .. 323 C/T rs114897963 - CDS Nonsynonymous[Thr108Met]
345 .. 345 A/G rs115445925 - CDS Synonymous[Gln115Gln]
485 .. 485 C/T rs141431061 - CDS Nonsynonymous[Ala162Val]
493 .. 493 G/A rs138503054 - CDS Nonsynonymous[Ala165Thr]
500 .. 500 C/A rs140129786 - CDS Nonsynonymous[Thr167Lys]
546 .. 546 T/G rs199908987 - CDS Synonymous[Thr182Thr]
571 .. 571 G/A rs149050833 - CDS Nonsynonymous[Ala191Thr]
574 .. 574 A/G rs145267894 - CDS Nonsynonymous[Thr192Ala]
600 .. 600 G/A rs115476558 - CDS Synonymous[Pro200Pro]
657 .. 657 C/A rs4985 + CDS Nonsynonymous[Ser219Arg]
668 .. 668 G/A rs147439886 - CDS Nonsynonymous[Ser223Asn]
693 .. 693 G/A rs139265334 - CDS Synonymous[Thr231Thr]
813 .. 813 G/A rs141473907 - CDS Synonymous[Leu271Leu]
815 .. 815 A/T rs138841596 - CDS Nonsynonymous[Lys272Ile]
889 .. 889 C/G rs144829163 - 3'UTR
1054 .. 1054 C/A rs115570420 - 3'UTR
1268 .. 1268 C/T rs1043136 + 3'UTR
1557 .. 1557 C/T rs149831214 - 3'UTR
1605 .. 1605 T/C rs186901862 - 3'UTR
1756 .. 1756 C/T rs34662357 - 3'UTR
1795 .. 1795 G/A rs35480486 - 3'UTR
1806 .. 1806 C/T rs139845720 - 3'UTR
1815 .. 1815 T/C rs13384050 - 3'UTR
1847 .. 1847 C/T rs115824829 - 3'UTR
1855 .. 1855 G/A rs147275057 - 3'UTR
1899 .. 1899 A/G rs183004119 - 3'UTR
1908 .. 1908 T/C rs17698193 - 3'UTR
2034 .. 2034 G/A rs143938189 - 3'UTR
2082 .. 2082 G/A rs72899633 - 3'UTR
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
Type Start End Strand
MIR3 969 1133 -
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene Repeat mask viewerRepeat Mask Viewer