H-InvDB_9.0 released on May 27, 2015.
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Definition*
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---
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H-Invitational ID:
HIT000221284
Accession number:
U76308
Created date:
26-Mar-2013
Last modified:
27-May-2015
Definition:
Serine/threonine-protein kinase ATR; EC=2.7.11.1; Ataxia telangiectasia and Rad3-related protein; FRAP-related protein 1;
Select format
Flat file
XML file
Nucleotide sequence fasta
Protein sequence fasta
Transcript annotation summary
H-Inv ID
HIT000221284
H-Inv cluster ID
HIX0030886
H-Inv protein ID
HIP000055785
Accession number
U76308.1
CAGE tag ID
NA
EST ID
NA
Genomic location
Chromosome
3
Location
3q23
Position
142168079- 142297625
Strand
-
Transcript feature
NO;
Coding potential
Protein coding;
Definition
Serine/threonine-protein kinase ATR; EC=2.7.11.1; Ataxia telangiectasia and Rad3-related protein; FRAP-related protein 1;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
Q13535
) [Identity/coverage = 99.962%/100.0%] to Homo sapiens (Human). protein.
Gene family / group
NA
Gene symbol/name
HGNC symbol
ATR
HGNC aliases
"ataxia telangiectasia and Rad3 related"
HGNC name
ATR serine/threonine kinase
DDBJ
NA
UniProt
ATR
EC number
EC 2.7.11.1
non-specific serine/threonine protein kinase;
KEGG metabolic pathway
04150
:mTOR signaling pathway;
04210
:Apoptosis;
04310
:Wnt signaling pathway;
04320
:Dorso-ventral axis formation;
04340
:Hedgehog signaling pathway;
04350
:TGF-beta signaling pathway;
04360
:Axon guidance;
04370
:VEGF signaling pathway;
04510
:Focal adhesion;
04520
:Adherens junction;
04530
:Tight junction;
04540
:Gap junction;
04620
:Toll-like receptor signaling pathway;
04630
:Jak-STAT signaling pathway;
04660
:T cell receptor signaling pathway;
04662
:B cell receptor signaling pathway;
04664
:Fc epsilon RI signaling pathway;
04720
:Long-term potentiation;
04730
:Long-term depression;
04810
:Regulation of actin cytoskeleton;
04910
:Insulin signaling pathway;
04912
:GnRH signaling pathway;
04920
:Adipocytokine signaling pathway;
05010
:Alzheimer's disease;
05210
:Colorectal cancer;
PubMed ID
8610130
;
8843195
;
8978690
;
9427750
;
9636169
;
9766667
;
9925639
;
10545197
;
10597277
;
10608806
;
10859164
;
11114888
;
11418864
;
11470508
;
11673449
;
11721054
;
11865061
;
12011431
;
12526805
;
12640452
;
12766152
;
12791985
;
12814551
;
14657349
;
14729973
;
14742437
;
14871897
;
15050919
;
15210935
;
15314022
;
15496423
;
15680327
;
15758953
;
17344846
;
18283122
;
18669648
;
18691976
;
20427287
;
20801936
;
20810650
;
21269460
;
21406692
;
22341969
;
ALL
;
Related H-InvDB links
Similarity Search Tool
Database links
RefSeq
NA
Ensembl
NA
Entrez Gene
Entrez Gene ID:545
;
KEGG GENES
KEGG GENES(545)
;
GeneCard
ATR
;
*GeneCards is provided free to academic non-profit institutions.
etc
Human-Gene diversity Of Life-style related Diseases
;
Curation status
Auto-annotated
Notes
NA