H-InvDB_9.0 released on May 27, 2015.
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Definition*
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---
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H-Invitational ID:
HIT000222622
Accession number:
U92436
Created date:
26-Mar-2013
Last modified:
27-May-2015
Definition:
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; EC=3.1.3.16; EC=3.1.3.48; EC=3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog;
Select format
Flat file
XML file
Nucleotide sequence fasta
Protein sequence fasta
Transcript annotation summary
H-Inv ID
HIT000222622
H-Inv cluster ID
HIX0009010
H-Inv protein ID
HIP000105366
Accession number
U92436.1
CAGE tag ID
NA
EST ID
NA
Genomic location
Chromosome
10
Location
10q23.31
Position
89623195- 89726132
Strand
+
Transcript feature
Representative transcript;
Splicing isoform
Coding potential
Protein coding;
Definition
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; EC=3.1.3.16; EC=3.1.3.48; EC=3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P60484
) [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Gene family / group
NA
Gene symbol/name
HGNC symbol
PTEN
HGNC aliases
NA
HGNC name
phosphatase and tensin homolog
DDBJ
MMAC1
UniProt
PTEN
EC number
EC 3.1.3.16
phosphoprotein phosphatase;
EC 3.1.3.48
protein-tyrosine-phosphatase;
EC 3.1.3.67
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase;
KEGG metabolic pathway
00562
:Inositol phosphate metabolism;
04020
:Calcium signaling pathway;
04070
:Phosphatidylinositol signaling system;
04210
:Apoptosis;
04310
:Wnt signaling pathway;
04350
:TGF-beta signaling pathway;
04360
:Axon guidance;
04370
:VEGF signaling pathway;
04510
:Focal adhesion;
04514
:Cell adhesion molecules (CAMs);
04520
:Adherens junction;
04530
:Tight junction;
04630
:Jak-STAT signaling pathway;
04660
:T cell receptor signaling pathway;
04662
:B cell receptor signaling pathway;
04670
:Leukocyte transendothelial migration;
04720
:Long-term potentiation;
04730
:Long-term depression;
04910
:Insulin signaling pathway;
04920
:Adipocytokine signaling pathway;
04940
:Type I diabetes mellitus;
05120
:Epithelial cell signaling in Helicobacter pylori infection;
PubMed ID
9072974
;
9090379
;
9140396
;
9187108
;
9241266
;
9256433
;
9259288
;
9331071
;
9345101
;
9399897
;
9425889
;
9467011
;
9593664
;
9600246
;
9616126
;
9635567
;
9735393
;
9797362
;
9811831
;
9832031
;
9915974
;
10051160
;
10234502
;
10400993
;
10468583
;
10555148
;
10646847
;
10748157
;
10760291
;
10807691
;
10817502
;
10866302
;
10978354
;
11035045
;
11230179
;
11494117
;
11707428
;
11748304
;
11801303
;
12085208
;
12297295
;
12471211
;
14702039
;
15489334
;
15805158
;
15951562
;
16752378
;
17218260
;
17436248
;
18716620
;
19345329
;
19473982
;
20534535
;
20940307
;
21269460
;
ALL
;
Related H-InvDB links
Similarity Search Tool
Database links
RefSeq
NA
Ensembl
NA
Entrez Gene
Entrez Gene ID:5728
;
KEGG GENES
KEGG GENES(5728)
;
GeneCard
PTEN
;
*GeneCards is provided free to academic non-profit institutions.
etc
Human-Gene diversity Of Life-style related Diseases
;
Curation status
Human curated
Notes
NA