H-InvDB x AHG DB
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H-InvDB_9.0 released on May 27, 2015.
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H-Invitational ID: HIT000243594 Accession number: AF486421 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Similar to Beta-adducin isoform f.
 
 

Transcript original information
Accession number AF486421.1
CAGE tag ID NA
EST ID NA
Clone Number NA
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ; Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (ADD2) ; Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (ADD2);
Sequence data provider NA
Annotation project NA
Length of cDNA 876[bp] (No. of exon:7)[A:233 T:140 G:252 C:251]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type kidney
Develpmental stage fetus
Mini-G
Sequence quality information
CDS feature C-truncated
Kozak sequence NA
PolyA NA
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) NA
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0029808
Genomic location  G-integra Help Chromosome 2
Location 2p13.3
Position 70901801- 70933575
Strand -
Possible duplicated location(s) NA
Gene structure 7 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:119
KEGG GENES KEGG GENES(119)
GeneCard GeneCardADD2*GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000097055
Predicted CDS 38..876;  279[aa];  Orientation:+2; 
Codon Adaptation Index (CAI). 0.799

Motif information
ORF

length(279),orf(38:876)
MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQ
KKRVTMILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHA
VFPTSSMNVSMMTPINDLHTADSLNLAKGERLMRCKISSVYRLLDLYGWA
QLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKEVLEMRNKIREQN
RQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNP
FSQLTDQELEEYKKEVERKKLELDETGQE
a.a.
length
InterPro Name
length(187), motif(1:187) 187 IPR027773 Beta-adducin [Family]
length(62), motif(130:191) 62 IPR001303 Class II aldolase/adducin N-terminal [Domain]
length(58), motif(130:187) 58 IPR001303 Class II aldolase/adducin N-terminal [Domain]
length(63), motif(136:198) 63 IPR001303 Class II aldolase/adducin N-terminal [Domain]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000243594
H-Inv cluster ID Locus viewHIX0029808
Accession number AF486421.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help NO;  Splicing isoformSplicing isoform
Coding potential  Help Protein coding; 
Definition Similar to Beta-adducin isoform f.
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (NP_001171984)  [Identity/coverage = 100.0%/34.61%] to Homo sapiens protein.
Experimental evidence Protein evidence
PubMed ID NA
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol ADD2
HGNC aliases NA
HGNC name adducin 2 (beta)
DDBJ ADD2
UniProt NA
EC number NA
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000097055
No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:119
KEGG GENES KEGG GENES(119)
GeneCard GeneCardADD2*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Auto-annotated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool;  TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
NA

Gene ontology information
Cellular component cytoskeleton (GO:0005856); 

Subcellular localization information  Last modified:27-May-2015
WoLF PSORT cytosol;  nuclear;  extracellular; 
Target P Other
SOSUI soluble protein
TMHMM soluble protein
PTS1
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Gene expression information  H-ANGEL DNAProbeLocator Last modified:27-May-2015
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator
AceGene AGhsB140906; 
Affymetrix
GeneChip
HG-Focus NA
HG-U133 NA
HG-U133A NA
HG-U133A_2 NA
HG-U133B NA
HG-U133_Plus_2 NA
HG-U95 NA
HG-U95A NA
HG-U95B NA
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 2558767;  2558768;  2558772;  2558791;  2558792;  2558798;  2558799;  2558800;  2558801; 
HuGeneFL NA
Agilent Human 1A Oligo Microarray:PGID215 NA
Whole Human Genome Oligo Microarray:PGID247 NA
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
28 .. 28 C/T rs188664399 - 5'UTR
32 .. 32 G/A rs199889944 - 5'UTR
36 .. 36 A/G rs62642474 - 5'UTR
44 .. 44 G/A rs200519011 - CDS Nonsynonymous[Glu3Lys]
84 .. 84 A/G rs201443444 - CDS Nonsynonymous[Gln16Arg]
87 .. 87 G/A rs34241538 + CDS Nonsynonymous[Gly17Glu]
119 .. 119 G/A rs4986 + CDS Nonsynonymous[Asp28Asn]
154 .. 154 G/A rs141187526 - CDS Synonymous[Ala39Ala]
162 .. 162 G/A rs144732476 - CDS Nonsynonymous[Arg42Gln]
169 .. 169 C/G rs138167651 - CDS Nonsynonymous[Asp44Glu]
236 .. 236 C/T rs114456016 - CDS Synonymous[Leu67Leu]
243 .. 243 G/T rs149147182 - CDS Nonsynonymous[Gly69Val]
289 .. 289 C/A rs17006140 - CDS Synonymous[Ile84Ile]
298 .. 298 G/A rs144778680 - CDS Synonymous[Leu87Leu]
307 .. 307 C/T rs200212314 - CDS Synonymous[Ile90Ile]
308 .. 308 G/A rs150703767 - CDS Nonsynonymous[Ala91Thr]
330 .. 330 C/G rs4987 + CDS Nonsynonymous[Ser98Cys]
346 .. 346 G/A rs144423262 - CDS Synonymous[Pro103Pro]
425 .. 425 G/A rs75081591 - CDS Nonsynonymous[Glu130Lys]
434 .. 434 A/C rs145968821 - CDS Nonsynonymous[Met133Leu]
475 .. 475 C/G rs114904807 - CDS Synonymous[Leu146Leu]
537 .. 537 A/G rs138007719 - CDS Nonsynonymous[His167Arg]
583 .. 583 G/A rs150383515 - CDS Synonymous[Ala182Ala]
590 .. 590 C/T rs200581515 - CDS Synonymous[Leu185Leu]
621 .. 621 A/G rs112879637 - CDS Nonsynonymous[Lys195Arg]
628 .. 628 A/C rs145174076 - CDS Synonymous[Arg197Arg]
658 .. 658 G/C rs115841739 - CDS Synonymous[Ala207Ala]
685 .. 685 C/T rs148402316 - CDS Synonymous[Ser216Ser]
694 .. 694 C/G rs201133279 - CDS Synonymous[Ala219Ala]
702 .. 702 G/C rs149689098 - CDS Nonsynonymous[Ser222Thr]
705 .. 705 G/T rs114311724 - CDS Nonsynonymous[Arg223Leu]
746 .. 746 G/A rs139586218 - CDS Nonsynonymous[Glu237Lys]
774 .. 774 C/T rs114897963 - CDS Nonsynonymous[Thr246Met]
796 .. 796 A/G rs115445925 - CDS Synonymous[Gln253Gln]
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene Repeat mask viewerRepeat Mask Viewer