H-InvDB x AHG DB
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H-InvDB_9.0 released on May 27, 2015.
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H-Invitational ID: HIT000262654 Accession number: BC067496 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Histone H4;
 
 

Transcript original information
Accession number BC067496.1
CAGE tag ID NA
EST ID NA
Clone Number MGC:79352 IMAGE:7002103
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ; Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (HIST1H4I) ; Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (HIST1H4I);
Sequence data provider NA
Annotation project NA
Length of cDNA 364[bp] (No. of exon:1)[A:76 T:62 G:116 C:110]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type PCR rescued clones
Develpmental stage NA
Mini-G
Sequence quality information
CDS feature Complete CDS
Kozak sequence NA
PolyA NA
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) NA
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0005658
Genomic location  G-integra Help Chromosome 6
Location 6p22.1
Position 27107088- 27107450
Strand +
Possible duplicated location(s) NA
Gene structure 1 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:8294
KEGG GENES KEGG GENES(8294)
GeneCard GeneCardHIST1H4I*GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS;  G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000098400
Predicted CDS 1..312;  103[aa];  Orientation:+1; 
Codon Adaptation Index (CAI). 0.834

Motif information
ORF

length(103),orf(1:312)
MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGL
IYEETRGVLKVFLENVIRDAATYTEHAKRKTVTAMDVVYALKRQGRTLYG
FGG*
a.a.
length
InterPro Name
length(102), motif(2:103) 102 IPR009072 Histone-fold [Domain]
length(100), motif(3:102) 100 IPR009072 Histone-fold [Domain]
length(12), motif(5:16) 12 IPR001951 Histone H4 [Family]
length(5), motif(15:19) 5 IPR019809 Histone H4, conserved site [Conserved_site]
length(75), motif(16:90) 75 IPR001951 Histone H4 [Family]
length(20), motif(20:39) 20 IPR001951 Histone H4 [Family]
length(67), motif(28:94) 67 IPR007125 Histone core [Domain]
length(21), motif(40:60) 21 IPR001951 Histone H4 [Family]
length(15), motif(62:76) 15 IPR001951 Histone H4 [Family]
length(13), motif(77:89) 13 IPR001951 Histone H4 [Family]
length(12), motif(89:100) 12 IPR001951 Histone H4 [Family]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000262654
H-Inv cluster ID Locus viewHIX0005658
Accession number BC067496.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help NO; 
Coding potential  Help Protein coding; 
Definition Histone H4;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (P62805)  [Identity/coverage = 99.029%/100.0%] to Homo sapiens (Human). protein.
Experimental evidence Protein evidence
PubMed ID 1916825247445630357173340182631427476262187664735898803090316209119399943965611387442114487791208661812408966145744041457844915345777154893341552796315592455159515141596484616678110169599741708198317967882186696481960886119690332198187142006823121269460214066922172482921925322ALL
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol HIST1H4I
HGNC aliases "H4 histone family, member M", "histone 1, H4i"
HGNC name histone cluster 1, H4i
DDBJ HIST1H4I
UniProt HIST4H4
EC number NA
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000098400
No. of interaction 129
Interaction partner(s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
BIND 153992;  177961;  182216;  183262;  183265;  183266;  200016;  295234;  297476;  318900;  318905;  318910;  335969;  335973;  89741;  89745; 
DIP 135184E;  135188E;  135189E;  135190E;  137167E;  149E;  150E;  177021E;  177022E;  177023E;  177024E;  177025E;  177026E;  177027E;  177028E;  177029E;  177030E;  180095E;  87759E;  87760E; 
MINT MINT-19344;  MINT-2490745;  MINT-2829358;  MINT-2829504;  MINT-2829542;  MINT-2829576;  MINT-2829624;  MINT-2829876;  MINT-2829895;  MINT-2829913;  MINT-2830323;  MINT-2830357;  MINT-2830381;  MINT-2830405;  MINT-2981755;  MINT-2981779;  MINT-3296655;  MINT-48337;  MINT-48494;  MINT-49244;  MINT-49356;  MINT-4950280;  MINT-4950315;  MINT-56509;  MINT-6543302;  MINT-6543323;  MINT-6543349;  MINT-6665465;  MINT-7899812;  MINT-7900157;  MINT-7914854;  MINT-7989539;  MINT-7989824;  MINT-7989846;  MINT-7989865;  MINT-7989882;  MINT-8010325; 
HPRD 00146;  00303;  00313;  00528;  00823;  01277;  01574;  01778;  01861;  02183;  02227;  02228;  02457;  02583;  03143;  03183;  03245;  03326;  03465;  03485;  03490;  03494;  03684;  03965;  03995;  04072;  04075;  04078;  04231;  04232;  04255;  04257;  04424;  04531;  04538;  04540;  04955;  05021;  05130;  05131;  05149;  05496;  05569;  05610;  06780;  06789;  06992;  07105;  07513;  07535;  07536;  07601;  09023;  09045;  09094;  09246;  09539;  10024;  10912;  11873;  11897;  11899;  11901;  12531;  13006;  13657;  15094;  15476;  15981;  16246;  16459;  16460;  16872;  19599; 
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:8294
KEGG GENES KEGG GENES(8294)
GeneCard GeneCardHIST1H4I*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Auto-annotated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool;  TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
FR ID FR304324
Accession
Description
Location
PMID

Gene ontology information
Molecular function DNA binding (GO:0003677);  protein heterodimerization activity (GO:0046982); 
Biological process nucleosome assembly (GO:0006334); 
Cellular component nucleus (GO:0005634);  nucleosome (GO:0000786); 

Subcellular localization information  Last modified:27-May-2015
WoLF PSORT nuclear; 
Target P Other
SOSUI soluble protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified:27-May-2015
Start End PDB_ID E-value Identity Coverage SCOP_ID
24 103 1aoiB 2e-14 98.8 80/83 a.22.1.1
Related H-InvDB links GTOP GTOP

Gene expression information  H-ANGEL DNAProbeLocator Last modified:27-May-2015
Tissue-specific expression  H-ANGEL NA
Probe
information DNAProbeLocator
AceGene AGhsB011101; 
Affymetrix
GeneChip
HG-Focus NA
HG-U133 NA
HG-U133A NA
HG-U133A_2 NA
HG-U133B NA
HG-U133_Plus_2 NA
HG-U95 762_f_at; 
HG-U95A 762_f_at; 
HG-U95B NA
HG-U95C NA
HG-U95D NA
HG-U95E NA
HG-U95Av2 NA
HuEx-1_0 2899770;  2899771;  2946719; 
HuGeneFL AB000905_at; 
Agilent Human 1A Oligo Microarray:PGID215 A_23_P361347; 
Whole Human Genome Oligo Microarray:PGID247 A_24_P20873; 
Related H-InvDB links H-ANGELH-ANGEL DNAProbeLocatorDNAProbeLocator

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
29 .. 29 G/C rs140775845 + CDS Nonsynonymous[Gly10Ala]
64 .. 64 G/T rs143050720 + CDS Nonsynonymous[Val22Leu]
99 .. 99 A/G rs151220380 + CDS Synonymous[Pro33Pro]
166 .. 166 C/T rs200159567 + CDS Nonsynonymous[Arg56Cys]
170 .. 170 G/A rs140361782 + CDS Nonsynonymous[Gly57Glu]
192 .. 192 G/A rs150377743 + CDS Synonymous[Glu64Glu]
236 .. 236 G/A rs116193614 + CDS Nonsynonymous[Arg79His]
257 .. 257 A/G rs138088561 + CDS Nonsynonymous[Asp86Gly]
292 .. 292 C/G rs143646853 + CDS Nonsynonymous[Leu98Val]
306 .. 306 C/T rs61742445 + CDS Synonymous[Gly102Gly]
315 .. 315 G/A rs112207956 + 3'UTR
345 .. 345 A/T rs202114057 + 3'UTR
358 ^ 359 -/GGT rs201244252 + 3'UTR
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene Repeat mask viewerRepeat Mask Viewer