H-InvDB x AHG DB
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H-InvDB_9.0 released on May 27, 2015.
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H-Invitational ID: HIT000265782 Accession number: BC080193 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Receptor tyrosine-protein kinase erbB-2; EC=2.7.10.1; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; AltName: CD_antigen=CD340; Precursor;
 
 

Transcript annotation summary  Locus view Protein view G-integra DiseaseInfo Viewer H-ANGEL Evola PPI viewer VaryGene H-DBAS LEGENDA Gene family TACT
H-Inv ID HIT000265782
H-Inv cluster ID Locus viewHIX0039027
H-Inv protein ID protein viewHIP000001371
Accession number BC080193.1
CAGE tag ID NA
EST ID NA
Genomic location  G-integra Help Chromosome 17
Location 17q12
Position 37856333- 37884829
Strand +
Transcript feature  Help NO;  Splicing isoformSplicing isoform
Coding potential  Help Protein coding; 
Definition Receptor tyrosine-protein kinase erbB-2; EC=2.7.10.1; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; AltName: CD_antigen=CD340; Precursor;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (P04626)  [Identity/coverage = 98.354%/100.0%] to Homo sapiens (Human). protein.
Gene family / group NA
Gene symbol/name HGNC symbol ERBB2
HGNC aliases "v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog)", "v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2"
HGNC name erb-b2 receptor tyrosine kinase 2
DDBJ NA
UniProt ERBB2
EC number EC 2.7.10.1receptor protein-tyrosine kinase; 
KEGG metabolic pathway 04020 :Calcium signaling pathway;  04060 :Cytokine-cytokine receptor interaction;  04210 :Apoptosis;  04320 :Dorso-ventral axis formation;  04360 :Axon guidance;  04370 :VEGF signaling pathway;  04510 :Focal adhesion;  04520 :Adherens junction;  04540 :Gap junction;  04640 :Hematopoietic cell lineage;  04730 :Long-term depression;  04810 :Regulation of actin cytoskeleton;  04910 :Insulin signaling pathway;  04912 :GnRH signaling pathway;  04930 :Type II diabetes mellitus;  05050 :Dentatorubropallidoluysian atrophy (DRPLA);  05120 :Epithelial cell signaling in Helicobacter pylori infection;  05210 :Colorectal cancer; 
PubMed ID 29920892995967299997430035773039351809548881044141035807910593938108057251244409512610629129394021297558115093539151561511521073315380516154572491548933416314522167945791697883917081983173448461755400718669648186919761871909619299620193725872006823120696930209378542109771821190959214066922145458221555369ALL
Related H-InvDB links Similarity Search ToolSimilarity Search Tool
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:2064
KEGG GENES KEGG GENES(2064)
GeneCard GeneCardERBB2*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Auto-annotated
Notes NA
Mini-G