H-InvDB_9.0 released on May 27, 2015.
Search by
Keyword
H-Inv ID (HIT)
H-Inv cluster ID (HIX)
H-Inv protein ID (HIP)
H-Inv gene family/group (HIF)
Accession number
Chromosome number
Chromosome band
Definition*
Data source ID
---
CCDS ID
dbSNP ID (rs number)
EC number
Ensembl ID
EntrezGene ID
FR ID
FR Accession number
GO ID
GO name*
HGNC gene symbol
HGNC gene name*
InterPro ID
InterPro name*
OMIM ID
OMIM title*
Pathway ID
Pathway name*
RefSeq (gene) ID
RefSeq (protein) ID
SCOP ID
UniProt
for
Advanced Search
Home
Quick guide
Navi
BLAST
Site map
Download
Contact us
Help
H-Invitational ID:
HIT000265782
Accession number:
BC080193
Created date:
26-Mar-2013
Last modified:
27-May-2015
Definition:
Receptor tyrosine-protein kinase erbB-2; EC=2.7.10.1; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; AltName: CD_antigen=CD340; Precursor;
Select format
Flat file
XML file
Nucleotide sequence fasta
Protein sequence fasta
Transcript annotation summary
H-Inv ID
HIT000265782
H-Inv cluster ID
HIX0039027
H-Inv protein ID
HIP000001371
Accession number
BC080193.1
CAGE tag ID
NA
EST ID
NA
Genomic location
Chromosome
17
Location
17q12
Position
37856333- 37884829
Strand
+
Transcript feature
NO;
Splicing isoform
Coding potential
Protein coding;
Definition
Receptor tyrosine-protein kinase erbB-2; EC=2.7.10.1; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; AltName: CD_antigen=CD340; Precursor;
Similarity category
Category: Identical to known human protein(Category I).
Identical to known human protein (
P04626
) [Identity/coverage = 98.354%/100.0%] to Homo sapiens (Human). protein.
Gene family / group
NA
Gene symbol/name
HGNC symbol
ERBB2
HGNC aliases
"v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog)", "v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2"
HGNC name
erb-b2 receptor tyrosine kinase 2
DDBJ
NA
UniProt
ERBB2
EC number
EC 2.7.10.1
receptor protein-tyrosine kinase;
KEGG metabolic pathway
04020
:Calcium signaling pathway;
04060
:Cytokine-cytokine receptor interaction;
04210
:Apoptosis;
04320
:Dorso-ventral axis formation;
04360
:Axon guidance;
04370
:VEGF signaling pathway;
04510
:Focal adhesion;
04520
:Adherens junction;
04540
:Gap junction;
04640
:Hematopoietic cell lineage;
04730
:Long-term depression;
04810
:Regulation of actin cytoskeleton;
04910
:Insulin signaling pathway;
04912
:GnRH signaling pathway;
04930
:Type II diabetes mellitus;
05050
:Dentatorubropallidoluysian atrophy (DRPLA);
05120
:Epithelial cell signaling in Helicobacter pylori infection;
05210
:Colorectal cancer;
PubMed ID
2992089
;
2995967
;
2999974
;
3003577
;
3039351
;
8095488
;
8104414
;
10358079
;
10593938
;
10805725
;
12444095
;
12610629
;
12939402
;
12975581
;
15093539
;
15156151
;
15210733
;
15380516
;
15457249
;
15489334
;
16314522
;
16794579
;
16978839
;
17081983
;
17344846
;
17554007
;
18669648
;
18691976
;
18719096
;
19299620
;
19372587
;
20068231
;
20696930
;
20937854
;
21097718
;
21190959
;
21406692
;
21454582
;
21555369
;
ALL
;
Related H-InvDB links
Similarity Search Tool
Database links
RefSeq
NA
Ensembl
NA
Entrez Gene
Entrez Gene ID:2064
;
KEGG GENES
KEGG GENES(2064)
;
GeneCard
ERBB2
;
*GeneCards is provided free to academic non-profit institutions.
etc
Human-Gene diversity Of Life-style related Diseases
;
Curation status
Auto-annotated
Notes
NA