H-InvDB x AHG DB
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H-Invitational ID: HIT000383486 Accession number: AB065881 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Olfactory receptor 4K1; Olfactory receptor OR14-19;
 
 

Transcript original information
Accession number AB065881.1
CAGE tag ID NA
EST ID NA
Clone Number NA
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ;
Sequence data provider NA
Annotation project NA
Length of cDNA 1336[bp] (No. of exon:1)[A:323 T:498 G:258 C:257]
Devision HUM
Molecular type DNA
Library origin Cell type NA
Tissue type NA
Develpmental stage NA
Mini-G
Sequence quality information
CDS feature Complete CDS
Kozak sequence NA
PolyA NA
Vector/adapter sequence NA
Frame shift NA
Remaining intron NA
Splice site acceptor (NAGNAG) NA
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0037778
Genomic location  G-integra Help Chromosome 14
Location 14q11.2
Position 20403626- 20404961
Strand +
Possible duplicated location(s) NA
Gene structure 1 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene NA
KEGG GENES NA
GeneCard NA *GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS;  G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000028391
Predicted CDS 201..1136;  311[aa];  Orientation:+3; 
Codon Adaptation Index (CAI). 0.727
Database links RefSeq NP_001004063
UniProt Q8NGD4
CCDS CCDS32025

Motif information
ORF

length(311),orf(201:1136)
MAHTNESMVSEFVLLGLSNSWGLQLFFFAIFSIVYVTSVLGNVLIIVIIS
FDSHLNSPMYFLLSNLSFIDICQSNFATPKMLVDFFIERKTISFEGCMAQ
IFVLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMNRRLCVIFVSISWA
VGVLHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYEMEIMTL
TNSGLISLSCFLALIISYTIILIGVRCRSSSGSSKALSTLTAHITVVILF
FGPCIYFYIWPFSRLPVDKFLSVFYTVCTPLLNPIIYSLRNEDVKAAMWK
LRNRHVNSWKN*
a.a.
length
InterPro Name
length(301), motif(2:302) 301 IPR017452 GPCR, rhodopsin-like, 7TM [Domain]
length(25), motif(26:50) 25 IPR000276 G protein-coupled receptor, rhodopsin-like [Family]
length(247), motif(41:287) 247 IPR017452 GPCR, rhodopsin-like, 7TM [Domain]
length(12), motif(92:103) 12 IPR000725 Olfactory receptor [Family]
length(23), motif(104:126) 23 IPR000276 G protein-coupled receptor, rhodopsin-like [Family]
length(17), motif(110:126) 17 IPR000276 G protein-coupled receptor, rhodopsin-like [Family]
length(13), motif(129:141) 13 IPR000725 Olfactory receptor [Family]
length(17), motif(176:192) 17 IPR000725 Olfactory receptor [Family]
length(10), motif(235:244) 10 IPR000725 Olfactory receptor [Family]
length(27), motif(269:295) 27 IPR000276 G protein-coupled receptor, rhodopsin-like [Family]
length(12), motif(280:291) 12 IPR000725 Olfactory receptor [Family]

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000383486
H-Inv cluster ID Locus viewHIX0037778
Accession number AB065881.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help Representative H-Inv IDRepresentative transcript; 
Coding potential  Help Protein coding; 
Definition Olfactory receptor 4K1; Olfactory receptor OR14-19;
Similarity category  Help Category: Identical to known human protein(Category I).
Identical to known human protein (Q8NGD4)  [Identity/coverage = 100.0%/100.0%] to Homo sapiens (Human). protein.
Experimental evidence Expression evidence
PubMed ID 122131991498305215489334ALL
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol NA
HGNC aliases NA
HGNC name NA
DDBJ NA
UniProt OR4K1
EC number NA
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000028391
No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene NA
KEGG GENES NA
GeneCard NA *GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Human curated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
NA

Gene ontology information
Molecular function olfactory receptor activity (GO:0004984);  G-protein coupled receptor activity (GO:0004930); 
Biological process G-protein coupled receptor protein signaling pathway (GO:0007186); 
Cellular component integral to membrane (GO:0016021); 

Subcellular localization information  Last modified:27-May-2015
WoLF PSORT plasma membrane; 
Target P signal peptide
SOSUI membrane protein
TMHMM membrane protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified:27-May-2015
Start End PDB_ID E-value Identity Coverage SCOP_ID
51 141 1f88A 4e-11 18.7 91/100 f.13.1.2
Related H-InvDB links GTOP GTOP

Evolutionary information  Evola Help Last modified:27-May-2015
Relationship Species Accession number MGI Links
Orthology Bos sp. (Cow) ENSBTAT00000011897 G-integraG-integra
Orthology Canis sp. (Dog) ENSCAFT00000037471 G-integraG-integra
Orthology Monodelphis sp. (Opossum) ENSMODT00000036017 G-integraG-integra
Orthology Mus sp. (Mouse) ENSMUST00000111705 G-integraG-integra
Orthology Rattus sp. (Rat) NM_001001015 G-integraG-integra
Orthology Macaca sp. (Macaque) XM_001086899 G-integraG-integra
Orthology Equus sp. (Horse) XM_001502381 G-integraG-integra
Orthology Pan sp. (Chimpanzee) XM_528680 G-integraG-integra
Phylogenetic tree [View by ATV]
Neighbor-joining (phb) 
Related H-InvDB links EvolaEvoladN/dS (under constraction); 

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
18 .. 18 G/T rs114157040 + 5'UTR
78 .. 78 T/C rs8015196 + 5'UTR
156 .. 156 A/G rs181541566 + 5'UTR
175 .. 175 T/A rs185952173 + 5'UTR
220 .. 220 C/T rs146809169 + CDS Nonsynonymous[Ser7Leu]
251 .. 251 C/T rs140568356 + CDS Synonymous[Leu17Leu]
264 .. 264 G/A rs192372732 + CDS Nonsynonymous[Gly22Arg]
284 .. 284 T/C rs2792148 - CDS Synonymous[Phe28Phe]
296 .. 296 T/C rs150032750 + CDS Synonymous[Ser32Ser]
340 .. 340 T/C rs145431678 + CDS Nonsynonymous[Val47Ala]
368 .. 368 C/T rs183683528 + CDS Synonymous[Asn56Asn]
403 .. 403 T/G rs141613150 + CDS Nonsynonymous[Phe68Cys]
419 .. 419 G/T rs149219228 + CDS Nonsynonymous[Gln73His]
421 .. 421 C/G rs147067678 + CDS Nonsynonymous[Ser74Cys]
442 .. 442 T/C rs137923524 + CDS Nonsynonymous[Met81Thr]
451 .. 451 A/T rs114526346 + CDS Nonsynonymous[Asp84Val]
455 .. 455 T/C rs145897406 + CDS Synonymous[Phe85Phe]
457 .. 457 T/C rs138714506 + CDS Nonsynonymous[Phe86Ser]
465 .. 465 C/T rs147602385 + CDS Nonsynonymous[Arg89Cys]
466 .. 466 G/A rs12885778 + CDS Nonsynonymous[Arg89His]
475 .. 475 T/A rs150770939 + CDS Nonsynonymous[Ile92Asn]
544 .. 544 T/C rs138010696 + CDS Nonsynonymous[Leu115Pro]
578 .. 578 A/G rs112535936 + CDS Nonsynonymous[Ile126Met]
613 .. 613 G/A rs3916626 - CDS Nonsynonymous[Arg138Gln]
614 .. 614 G/A rs146020418 + CDS Synonymous[Arg138Arg]
657 .. 657 G/A rs200187960 + CDS Nonsynonymous[Val153Ile]
694 .. 694 A/C rs79774363 + CDS Nonsynonymous[Asp165Ala]
705 .. 705 T/G rs140036244 + CDS Nonsynonymous[Cys169Gly]
706 .. 706 G/C rs143569024 + CDS Nonsynonymous[Cys169Ser]
715 .. 715 A/G rs75008557 + CDS Nonsynonymous[Asn172Ser]
719 .. 719 G/A rs150151690 + CDS Synonymous[Glu173Glu]
751 .. 751 T/G rs138642977 + CDS Nonsynonymous[Val184Gly]
762 .. 762 G/T rs142845996 + CDS Nonsynonymous[Ala188Ser]
765 .. 765 T/C rs201484529 + CDS Nonsynonymous[Cys189Arg]
769 .. 769 T/A rs151092355 + CDS Nonsynonymous[Met190Lys]
770 .. 770 G/A rs74705836 + CDS Nonsynonymous[Met190Ile]
776 .. 776 A/G rs190776502 + CDS Synonymous[Thr192Thr]
786 .. 786 G/A rs149331048 + CDS Nonsynonymous[Glu196Lys]
802 .. 802 C/T rs200761942 + CDS Nonsynonymous[Thr201Met]
803 .. 803 G/A rs149331677 + CDS Synonymous[Thr201Thr]
807 .. 807 A/G rs201955766 + CDS Nonsynonymous[Ser203Gly]
851 .. 851 C/G rs147951270 + CDS Synonymous[Ser217Ser]
869 .. 869 C/A rs141997601 + CDS Synonymous[Ile223Ile]
870 .. 870 G/A rs199618384 + CDS Nonsynonymous[Gly224Ser]
876 .. 876 C/T rs145757525 + CDS AA-STOP[Arg226*]
946 .. 946 T/A rs137893475 + CDS Nonsynonymous[Leu249His]
950 .. 950 C/T rs148851997 + CDS Synonymous[Phe250Phe]
953 .. 953 C/T rs142429554 + CDS Synonymous[Phe251Phe]
957 .. 957 C/A rs145971130 + CDS Nonsynonymous[Pro253Thr]
976 .. 976 T/C rs139885856 + CDS Nonsynonymous[Ile259Thr]
989 .. 989 C/A rs34608158 + CDS Nonsynonymous[Ser263Arg]
996 .. 996 C/T rs147347995 + CDS Nonsynonymous[Pro266Ser]
1029 .. 1029 G/A rs199701811 + CDS Nonsynonymous[Val277Ile]
1046 .. 1046 G/C rs141721875 + CDS Nonsynonymous[Leu282Phe]
1065 .. 1065 C/T rs2792147 - CDS Synonymous[Leu289Leu]
1096 .. 1096 G/A rs144917067 + CDS AA-STOP[Trp299*]
1110 .. 1110 C/T rs34394400 + CDS Nonsynonymous[Arg304Cys]
1111 .. 1111 G/A rs2792146 - CDS Nonsynonymous[Arg304His]
1133 .. 1133 C/T rs138753104 + CDS Synonymous[Asn311Asn]
1142 .. 1142 A/G rs2792145 - 3'UTR
1179 .. 1179 C/T rs201473467 + 3'UTR
1249 .. 1249 C/T rs2792144 - 3'UTR
1274 .. 1274 T/A rs79739578 + 3'UTR
1278 .. 1278 T/C rs112338643 + 3'UTR
1332 .. 1332 T/C rs182639993 + 3'UTR
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene;  Repeat mask viewerRepeat Mask Viewer