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H-InvDB_9.0 released on May 27, 2015.
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H-Invitational ID: HIT000488195 Accession number: AK293571 Created date: 26-Mar-2013 Last modified: 27-May-2015
Definition: Similar to Uncharacterized aarF domain-containing protein kinase 4; EC=2.7.11.-;
 
 

Transcript original information
Accession number AK293571.1
CAGE tag ID NA
EST ID NA
Clone Number BRACE2020515
Experimental resources NBRC: NITE Biological Resource Center  NBRC ; HGPD: Human Gene and Protein Database HGPD ; Antibody: searching human antibodies at "BIO-kaimono.com" Antibody (ADCK3) ; Catalog: searching experimental product catalogs at "BIO-kaimono.com" Catalog (ADCK3);
Sequence data provider NA
Annotation project NA
Length of cDNA 1725[bp] (No. of exon:12)[A:353 T:318 G:531 C:523]
Devision HUM
Molecular type mRNA
Library origin Cell type NA
Tissue type cerebellum
Develpmental stage NA
Mini-G
Sequence quality information
CDS feature Complete CDS
Kozak sequence NA
PolyA NA
Vector/adapter sequence NA
Frame shift 361-362[bp] Deletion(CCTCC); 362-363[bp] Deletion(C);
Remaining intron NA
Splice site acceptor (NAGNAG) NA
Transcript quality feature NA
Notes NA

Gene structure information  G-integra H-DBAS cDNA-genome alignment
H-Inv cluster ID HIX0001648
Genomic location  G-integra Help Chromosome 1
Location 1q42.13
Position 227127995- 227174678
Strand +
Possible duplicated location(s) NA
Gene structure 12 exon(s)
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:56997
KEGG GENES KEGG GENES(56997)
GeneCard GeneCardADCK3*GeneCards is provided free to academic non-profit institutions.
Related H-InvDB links H-DBASH-DBAS G-integraG-integra cDNA-genome alignmentcDNA-genome alignment

Predicted CDS information
HIP ID HIP000247312
Predicted CDS 541..1485;  314[aa];  Orientation:+1; 
Codon Adaptation Index (CAI). 0.853

Gene function information  Gene family PPI viewer Similarity Search Tool TACT
H-Inv ID HIT000488195
H-Inv cluster ID Locus viewHIX0001648
Accession number AK293571.1
CAGE tag ID NA
EST ID NA
Transcript feature  Help NO;  Splicing isoformSplicing isoform
Coding potential  Help Protein coding; 
Definition Similar to Uncharacterized aarF domain-containing protein kinase 4; EC=2.7.11.-;
Similarity category  Help Category: Similar to known protein(Category II).
Similar to known protein (Q96D53)  [Identity/coverage = 57.895%/96.69%] to Homo sapiens (Human). protein.
Experimental evidence Protein evidence
PubMed ID 14702039154893341734484621269460ALL
Gene family/group Gene family H-Inv gene family/group ID NA
Gene family/group name NA
Evidence motif (InterPro) ID NA
Gene symbol/name HGNC symbol ADCK3
HGNC aliases "chaperone-ABC1 (activity of bc1 complex, S.pombe)-like", "chaperone, ABC1 activity of bc1 complex like (S. pombe)", "chaperone, ABC1 activity of bc1 complex homolog (S. pombe)"
HGNC name aarF domain containing kinase 3
DDBJ NA
UniProt ADCK4
EC number EC 2.7.11.-Protein-serine/threonine kinases; 
GGDB
(GlycoGene Database)
Gene symbol NA
Familly NA
Designation NA
Expression NA
KEGG metabolic pathway NA
Protein-protein interaction (PPI) PPI viewer H-Inv protein ID HIP000247312
No. of interaction NA
Interaction partner(s) NA
BIND NA
DIP NA
MINT NA
HPRD NA
IntAct NA
Database links RefSeq NA
Ensembl NA
Entrez Gene Entrez Gene ID:56997
KEGG GENES KEGG GENES(56997)
GeneCard GeneCardADCK3*GeneCards is provided free to academic non-profit institutions.
etc H-GOLDHuman-Gene diversity Of Life-style related Diseases
Curation status Auto-annotated
Notes NA
Related H-InvDB links Gene familyGene family;  Similarity Search ToolSimilarity Search Tool;  TACTTACT
fRNAdb (The functional RNA database) : overlapping fRNAdb entries with H-InvDB transcripts based on the location of the genome. 
NA


Subcellular localization information  Last modified:27-May-2015
WoLF PSORT cytosol;  nuclear; 
Target P Not predicted
SOSUI soluble protein
TMHMM soluble protein
PTS1 Not targeted
Related H-InvDB links LIFEdb LIFEdb; 
JRE-1.4.0 or later is required. Download JRE at Sun's web site.

Protein structure information (GTOP) GTOP Last modified:27-May-2015
Start End PDB_ID E-value Identity Coverage SCOP_ID
112 153 1y74A1 1e-15 19.0 42/100 a.194.1.1
Related H-InvDB links GTOP GTOP

Polymorphism (SNP, indel), microsatellite (Short Tandem Repeat, STR) and repeat information  VaryGene Repeat mask viewer
 Single Nucleotide Polymorphism (SNP) and indel  VaryGene
Location Variation dbSNP ID Strand CDS/UTR Translation
116 .. 116 A/G rs199604256 + 5'UTR
126 .. 126 T/A rs202075418 + 5'UTR
150 .. 150 C/T rs200052870 + 5'UTR
165 .. 165 A/G rs150221608 + 5'UTR
177 .. 177 C/T rs142184584 + 5'UTR
178 .. 178 G/A rs11549709 + 5'UTR
182 .. 182 G/A rs35582308 + 5'UTR
193 .. 193 C/T rs150541057 + 5'UTR
211 .. 211 C/T rs199919057 + 5'UTR
215 .. 215 G/A rs142125927 + 5'UTR
232 .. 232 G/A rs11549708 + 5'UTR
252 .. 252 C/T rs187123516 + 5'UTR
286 .. 286 G/C rs200123840 + 5'UTR
346 .. 346 G/A rs201037948 + 5'UTR
353 .. 353 C/T rs76249490 + 5'UTR
355 .. 355 C/T rs113667144 + 5'UTR
356 .. 356 T/C rs200349511 + 5'UTR
367 .. 367 G/T rs200000374 + 5'UTR
373 .. 373 G/T rs150696959 + 5'UTR
400 .. 400 C/G rs201479287 + 5'UTR
410 .. 410 G/A rs147889685 + 5'UTR
459 .. 459 C/T rs139970507 + 5'UTR
477 .. 477 C/T rs200182503 + 5'UTR
542 .. 542 T/C rs147812454 + CDS Nonsynonymous[Met1Thr]
547 .. 547 T/C rs142652509 + CDS Nonsynonymous[Phe3Leu]
596 .. 596 C/A rs181579601 + CDS Nonsynonymous[Thr19Lys]
600 .. 600 C/T rs201787750 + CDS Synonymous[Ala20Ala]
639 .. 639 C/T rs140897240 + CDS Synonymous[Pro33Pro]
662 .. 662 C/T rs200762439 + CDS Nonsynonymous[Thr41Met]
669 .. 669 C/T rs138547552 + CDS Synonymous[Ser43Ser]
676 .. 676 G/T rs188599627 + CDS Nonsynonymous[Ala46Ser]
680 .. 680 G/A rs145350362 + CDS Nonsynonymous[Arg47Gln]
686 .. 686 G/A rs200541514 + CDS Nonsynonymous[Arg49Gln]
693 .. 693 G/A rs115855910 + CDS Synonymous[Val51Val]
712 .. 712 C/T rs119468005 + CDS Nonsynonymous[Arg58Trp]
754 .. 754 G/A rs199694417 + CDS Nonsynonymous[Gly72Arg]
798 .. 798 C/- rs35757883 + CDS
805 .. 805 G/C rs199619932 + CDS Nonsynonymous[Gly89Arg]
817 .. 817 G/A rs148376283 + CDS Nonsynonymous[Val93Met]
820 .. 820 C/T rs199958142 + CDS Synonymous[Leu94Leu]
855 .. 855 A/G rs147447166 + CDS Synonymous[Ala105Ala]
860 .. 860 G/A rs145422777 + CDS Nonsynonymous[Arg107Gln]
869 .. 869 G/A rs199696414 + CDS Nonsynonymous[Arg110His]
872 .. 872 C/T rs149924675 + CDS Nonsynonymous[Thr111Met]
886 .. 886 C/T rs145034527 + CDS Nonsynonymous[Arg116Cys]
890 .. 890 G/A/T rs119468006 + CDS
929 .. 929 A/C rs143493998 + CDS Nonsynonymous[Asp130Ala]
948 .. 948 C/T rs200849486 + CDS Synonymous[Pro136Pro]
951 .. 951 C/G rs200155917 + CDS Nonsynonymous[His137Gln]
966 .. 966 C/T rs55968053 + CDS Synonymous[Phe142Phe]
970 .. 970 C/T rs201908721 + CDS Nonsynonymous[Arg144Trp]
976 .. 976 C/T rs140246430 + CDS Nonsynonymous[Arg146Trp]
984 .. 984 C/T rs202036077 + CDS Synonymous[Ser148Ser]
1020 .. 1020 C/A rs150918577 + CDS Nonsynonymous[Asn160Lys]
1074 .. 1074 G/A rs201337210 + CDS Synonymous[Thr178Thr]
1075 .. 1075 C/T rs149682899 + CDS Nonsynonymous[Arg179Trp]
1076 .. 1076 G/A rs200115323 + CDS Nonsynonymous[Arg179Gln]
1082 .. 1082 A/G rs119468008 + CDS Nonsynonymous[Tyr181Cys]
1097 .. 1097 C/G rs141260985 + CDS Nonsynonymous[Thr186Ser]
1108 .. 1108 A/G rs147730489 + CDS Nonsynonymous[Ile190Val]
1132 .. 1132 G/A rs200930703 + CDS Nonsynonymous[Asp198Asn]
1146 .. 1146 G/C rs201158713 + CDS Nonsynonymous[Glu202Asp]
1147 .. 1147 A/G rs200403220 + CDS Nonsynonymous[Thr203Ala]
1151 .. 1151 T/G rs199724504 + CDS Nonsynonymous[Val204Gly]
1153 .. 1153 C/T rs201331131 + CDS Nonsynonymous[Arg205Trp]
1158 .. 1158 G/A rs142600066 + CDS Synonymous[Ala206Ala]
1185 .. 1185 C/T rs141423403 + CDS Synonymous[Thr215Thr]
1186 .. 1186 G/A rs119468009 + CDS Nonsynonymous[Gly216Ser]
1192 .. 1192 G/A rs119468004 + CDS Nonsynonymous[Glu218Lys]
1206 .. 1206 G/A rs199874519 + CDS Nonsynonymous[Met222Ile]
1213 .. 1213 G/A rs142894121 + CDS Nonsynonymous[Ala225Thr]
1218 .. 1218 C/G rs200963031 + CDS Nonsynonymous[His226Gln]
1251 .. 1251 C/T rs139305619 + CDS Synonymous[Phe237Phe]
1257 .. 1257 T/C rs3738725 + CDS Synonymous[Ser239Ser]
1261 .. 1261 G/A rs202058665 + CDS Nonsynonymous[Glu241Lys]
1280 .. 1280 C/T rs199581236 + CDS Nonsynonymous[Thr247Ile]
1293 .. 1293 C/T rs201865243 + CDS Synonymous[Thr251Thr]
1296 .. 1296 G/C rs201171077 + CDS Nonsynonymous[Glu252Asp]
1298 .. 1298 A/G rs113308613 + CDS Nonsynonymous[Lys253Arg]
1306 .. 1306 A/C rs142051104 + CDS Nonsynonymous[Asn256His]
1317 .. 1317 C/T rs7545723 + CDS Synonymous[Pro259Pro]
1338 .. 1338 C/T rs139551241 + CDS Synonymous[Leu266Leu]
1341 .. 1341 C/G rs74589348 + CDS Synonymous[Val267Val]
1346 .. 1346 C/A/G rs61995958 + CDS
1357 .. 1357 A/C rs143650593 + CDS Nonsynonymous[Thr273Pro]
1362 .. 1362 C/T rs201618750 + CDS Synonymous[Tyr274Tyr]
1365 .. 1365 C/T rs141270350 + CDS Synonymous[Ser275Ser]
1407 .. 1407 G/A rs191944347 + CDS Synonymous[Lys289Lys]
1417 .. 1417 C/T rs141725964 + CDS Nonsynonymous[Arg293Cys]
1440 .. 1440 C/T rs150569155 + CDS Synonymous[Phe300Phe]
1441 .. 1441 G/A rs149335528 + CDS Nonsynonymous[Glu301Lys]
1455 .. 1455 C/T rs56043893 + CDS Synonymous[Ser305Ser]
1494 .. 1494 G/A rs200743857 + 3'UTR
1618 .. 1618 G/A rs149820067 + 3'UTR
1715 .. 1715 G/A rs117808661 + 3'UTR
1719 .. 1719 G/A rs188462608 + 3'UTR
 Microsatellite (Short Tandem Repeat, STR)
No data available
 Microsatellite: Human-Gene diversity Of Life-style related Diseases (H-GOLD)
No data available
 Repeat  Repeat mask viewer
No data available
Database links H-GOLDHuman-Gene diversity Of Life-style related Diseases(H-GOLD)
Related H-InvDB links VaryGeneVaryGene Repeat mask viewerRepeat Mask Viewer