H-Inv ID |
HIT000497748 |
H-Inv cluster ID |
HIX0021256
|
H-Inv protein ID |
HIP000256412
|
Accession number |
AK303124.1
|
CAGE tag ID |
NA
|
EST ID |
NA
|
Genomic location
|
Chromosome |
1 |
Location |
1p13.2
|
Position |
114357301-
114414330
|
Strand |
-
|
Transcript feature
|
NO;
Splicing isoform
|
Coding potential
|
Protein coding;
|
Definition |
Similar to Tyrosine-protein phosphatase non-receptor type 22; EC=3.1.3.48; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; LyP; PEST-domain phosphatase; PEP; |
Similarity category
|
Category: Similar to known protein(Category II).
|
Similar to known protein (Q9Y2R2)
[Identity/coverage = 99.827%/71.75%] to
Homo sapiens (Human). protein.
|
Gene family / group |
NA
|
Gene symbol/name |
HGNC symbol |
PTPN22
|
HGNC aliases |
"protein tyrosine phosphatase, non-receptor type 8"
|
HGNC name |
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
|
DDBJ |
NA
|
UniProt |
PTPN22
|
EC number |
EC 3.1.3.48protein-tyrosine-phosphatase;
|
KEGG metabolic pathway |
04514
:Cell adhesion molecules (CAMs);
04520
:Adherens junction;
04630
:Jak-STAT signaling pathway;
04660
:T cell receptor signaling pathway;
04662
:B cell receptor signaling pathway;
04670
:Leukocyte transendothelial migration;
04910
:Insulin signaling pathway;
04920
:Adipocytokine signaling pathway;
04940
:Type I diabetes mellitus;
05120
:Epithelial cell signaling in Helicobacter pylori infection;
|
PubMed ID |
10068674;
14702039;
15004560;
15273934;
15489334;
16461343;
16710414;
17729039;
18056643;
19167335;
19371084;
21719704;
22427951;
ALL;
|
Related H-InvDB links |
Similarity Search Tool
|
Database links |
RefSeq |
NA
|
Ensembl |
NA
|
Entrez Gene |
Entrez Gene ID:26191;
|
KEGG GENES |
KEGG GENES(26191);
|
GeneCard |
PTPN22;
*GeneCards is provided free to academic non-profit institutions.
|
etc |
Human-Gene diversity Of Life-style related Diseases;
|
Curation status |
Auto-annotated
|
Notes |
NA
|